Editing Adrenal gland (section)

====Zona glomerulosa====
The outermost zone of the adrenal cortex is the [[zona glomerulosa]]. It lies immediately under the fibrous capsule of the gland. Cells in this layer form oval groups, separated by [[trabeculae|thin strands]] of connective tissue from the fibrous capsule of the gland and carry wide [[capillary|capillaries]].<ref name="wheater">{{cite book | title=Wheater's Functional Histology: A Text and Colour Atlas | publisher=Elsevier |vauthors=Young B, Woodford P, O'Dowd G | year=2013 | isbn=978-0702047473 | page=329 | edition=6th}}</ref>

This layer is the main site for production of [[aldosterone]], a [[mineralocorticoid]], by the action of the enzyme [[aldosterone synthase]].<ref name="pmid1775135">{{cite journal |vauthors=Curnow KM, Tusie-Luna MT, Pascoe L, Natarajan R, Gu JL, Nadler JL, White PC |title=The product of the CYP11B2 gene is required for aldosterone biosynthesis in the human adrenal cortex. |journal=Mol. Endocrinol. |volume=5 |issue=10 |pages=1513–1522 |date=October 1991 |pmid=1775135 |doi= 10.1210/mend-5-10-1513 |url=https://academic.oup.com/mend/article-pdf/5/10/1513/10490358/mend1513.pdf |archive-url=https://ghostarchive.org/archive/20221009/https://academic.oup.com/mend/article-pdf/5/10/1513/10490358/mend1513.pdf |archive-date=2022-10-09 |url-status=live |doi-access=free }}</ref><ref name="pmid8333830">{{cite journal |vauthors=Zhou M, Gomez-Sanchez CE |title=Cloning and expression of a rat cytochrome P-450 11 beta-hydroxylase/aldosterone synthase (CYP11B2) cDNA variant. |journal=Biochem Biophys Res Commun |volume=194 |issue=1 |pages=112–117 |date=July 1993 |pmid=8333830 |doi= 10.1006/bbrc.1993.1792 }}</ref> Aldosterone plays an important role in the long-term [[regulation of blood pressure]].<ref name=marieb>{{cite book|last1=Marieb|first1=EN|last2=Hoehn|first2=K|title=Human anatomy & physiology|date=2012|publisher=Pearson|isbn=978-0321743268|pages=629|edition=9th}}</ref>