Editing Moctezuma II (section)

====Late stages====
With the Mexica forces to support Huejotzingo, the invasion continued from the west with the main force from the towns of Cuauhquechollan, [[Tochimilco]], Itzocan (today known as [[Izúcar de Matamoros]]), and a smaller support force from a town named Tetellan (today, [[Tetela de Ocampo]]) and from a town named [[Chietla]]. The advance was quick, but the Tlaxcalans used the territories they had captured from Huejotzingo to advance safely to Atlixco through the captured areas with little population before the Mexica-Huejotzingo forces spread.{{sfn|Muñoz Camargo|1892|pp=114–115}} Once done, a long fight began between the two forces. The battle lasted 20 days, and both armies suffered huge losses, as the Tlaxcalans had a famous general captured and the Mexica lost so many men that they requested emergency reinforcements, asking for "all kinds of people in the shortest possible time". The Tlaxcalans claimed victory in that fight, and the Mexica were fought into a complete standstill.{{sfn|Isaac|1983|p=422}} The following year, Huejotzingo started to suffer a famine as the result of a lack of resources as the Tlaxcalans pushed further into their territory. The Tlaxcalans even went as far as burning down the royal palaces of Huejotzingo and stealing as much food as they could.{{sfn|Muñoz Camargo|1892|p=115}}

Approximately in the year 1516, Huejotzingo abandoned its alliance with the empire.{{sfn|Isaac|1983|p=416}}

The devastating wars that broke out against Huejotzingo caused this nation, which had been the most powerful nation in the Valley of Puebla in the opening years of the 16th century, to become weak enough to be conquered by Tlaxcala. This was the point at which Tlaxcala became Mexico's most powerful rival in the central Mexican area. The nation which used to be their main military focus was now the subject of a nation that would later bring the killing blow to the Mexica Empire.{{sfn|Isaac|1983|pp=423–425}}

The war between Mexico and Tlaxcala would eventually have devastating consequences, as the Tlaxcalans decided an alliance with Spain against Mexico on 23 September 1519 after a few battles proved that an alliance with this nation could help them destroy Moctezuma's reign.{{sfn|Díaz del Castillo|2011|pp=227–228}}