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===United States=== {{update section|date=September 2021}} An estimated 13,170 new cervical cancers and 4,250 cervical cancer deaths will occur in the United States in 2019.<ref>{{Cite web|url=https://seer.cancer.gov/statfacts/html/cervix.html|title=Cancer Stat Facts: Cervical Cancer|website=National Cancer Institute SEER Program|access-date=4 June 2019}}</ref> The median age at diagnosis is 50. The rate of new cases in the United States was 7.3 per 100,000 women, based on rates from 2012 to 2016. Cervical cancer deaths decreased by approximately 74% in the last 50 years, largely due to widespread Pap test screening.<ref name=Armstrong10>{{cite journal | vauthors = Armstrong EP | title = Prophylaxis of cervical cancer and related cervical disease: a review of the cost-effectiveness of vaccination against oncogenic HPV types | journal = Journal of Managed Care Pharmacy | volume = 16 | issue = 3 | pages = 217β230 | date = April 2010 | pmid = 20331326 | doi = 10.18553/jmcp.2010.16.3.217 | pmc = 10437588 | s2cid = 14373353 }}</ref> The annual direct medical cost of cervical cancer prevention and treatment before the introduction of the HPV vaccine was estimated at $6 billion.<ref name=Armstrong10/>
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