Editing Caenorhabditis elegans (section)

== Scientific community ==
Several scientists have won the [[Nobel Prize in Physiology or Medicine]] for scientific discoveries made working with ''C. elegans''. It was awarded in 2002 to [[Sydney Brenner]], [[H. Robert Horvitz]], and [[John Sulston]] for their work on the genetics of organ development and [[apoptosis|programmed cell death]], in 2006 to [[Andrew Fire]] and [[Craig C. Mello]] for their discovery of [[RNA interference]], and in 2024 to [[Victor Ambros]] and [[Gary Ruvkun]] for their discovery of [[microRNA]] and its role in gene regulation.<ref>{{cite journal | vauthors = Fire A, Xu S, Montgomery MK, Kostas SA, Driver SE, Mello CC | title = Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans | journal = Nature | volume = 391 | issue = 6669 | pages = 806–11 | date = February 1998 | pmid = 9486653 | doi = 10.1038/35888 | bibcode = 1998Natur.391..806F | s2cid = 4355692 | url = http://www.dspace.cam.ac.uk/handle/1810/238264 }}</ref><ref name="p119">{{cite journal | last1=Callaway | first1=Ewen | last2=Sanderson | first2=Katharine | title=Medicine Nobel awarded for gene-regulating 'microRNAs' | journal=Nature | publisher=Nature Publishing Group | date=2024-10-07 | volume=634 | issue=8034 | pages=524–525 | doi=10.1038/d41586-024-03212-9 | pmid=39375555 | url=https://www.nature.com/articles/d41586-024-03212-9 | access-date=2024-10-08}}</ref>
In 2008, [[Martin Chalfie]] shared a [[Nobel Prize in Chemistry]] for his work on [[green fluorescent protein]]; some of the research involved the use of ''C. elegans''.

Many scientists who research ''C. elegans ''closely connect to Sydney Brenner, with whom almost all research in this field began in the 1970s; they have worked as either a [[postdoctoral]] or a [[postgraduate]] researcher in Brenner's lab or in the lab of someone who previously worked with Brenner. Most who worked in his lab later established their own worm research labs, thereby creating a fairly well-documented "lineage" of ''C. elegans'' scientists, which was recorded into the [[WormBase]] database in some detail at the 2003 International Worm Meeting.<ref name="Harris">{{cite journal | vauthors = Harris TW, Antoshechkin I, Bieri T, Blasiar D, Chan J, Chen WJ, De La Cruz N, Davis P, Duesbury M, Fang R, Fernandes J, Han M, Kishore R, Lee R, Müller HM, Nakamura C, Ozersky P, Petcherski A, Rangarajan A, Rogers A, Schindelman G, Schwarz EM, Tuli MA, Van Auken K, Wang D, Wang X, Williams G, Yook K, Durbin R, Stein LD, Spieth J, Sternberg PW | display-authors = 6 | title = WormBase: a comprehensive resource for nematode research | journal = Nucleic Acids Research | volume = 38 | issue = Database issue | pages = D463-7 | date = January 2010 | pmid = 19910365 | pmc = 2808986 | doi = 10.1093/nar/gkp952 }}</ref>