Editing Anaphylaxis (section)

==Epidemiology==
The number of people who get anaphylaxis is 4–100 per 100,000 persons per year,<ref name=CEA11/><ref name=Tej2015>{{cite journal|last1=Tejedor-Alonso M|first1=A|last2=Moro-Moro|first2=M|last3=Múgica-García|first3=MV|title=Epidemiology of Anaphylaxis: Contributions From the Last 10 Years.|journal=Journal of Investigational Allergology & Clinical Immunology|date=2015|volume=25|issue=3|pages=163–75; quiz follow 174–5|pmid=26182682}}</ref> with a [[Cumulative incidence|lifetime risk]] of 0.05–2%.<ref>{{cite book|author1=Leslie C. Grammer|title=Patterson's Allergic Diseases|date=2012|publisher=Lippincott Williams & Wilkins |isbn=9781451148633|edition=7|url=https://books.google.com/books?id=MWdT7W4_N8sC&pg=PA199|url-status=live|archive-url=https://web.archive.org/web/20150620140057/https://books.google.ca/books?id=MWdT7W4_N8sC&pg=PA199|archive-date=2015-06-20}}</ref> About 30% of affected people get more than one attack.<ref name=Tej2015/> Exercise-induced anaphylaxis affects about 1 in 2000 young people.<ref name=Pravetton2016rev/>

Rates appear to be increasing: the numbers in the 1980s were approximately 20 per 100,000 per year, while in the 1990s it was 50 per 100,000 per year.<ref name=Review09/> The increase appears to be primarily for food-induced anaphylaxis.<ref>{{cite journal|last=Koplin|first=JJ|author2=Martin, PE |author3=Allen, KJ|title=An update on epidemiology of anaphylaxis in children and adults|journal=Current Opinion in Allergy and Clinical Immunology|date=October 2011|volume=11|issue=5|pages=492–6|pmid=21760501|doi=10.1097/ACI.0b013e32834a41a1|s2cid=13164564}}</ref> The risk is greatest in young people and females.<ref name=EAACI2014/><ref name=CEA11/>

Anaphylaxis leads to as many as 500–1,000 deaths per year (2.7 per million) in the United States, 20 deaths per year in the United Kingdom (0.33 per million), and 15 deaths per year in Australia (0.64 per million).<ref name=CEA11/> Another estimate from the United States puts the death rate at 0.7 per million.<ref>{{cite journal|last1=Fromer|first1=L|title=Prevention of Anaphylaxis: The Role of the Epinephrine Auto-Injector.|journal=The American Journal of Medicine|date=December 2016|volume=129|issue=12|pages=1244–1250|doi=10.1016/j.amjmed.2016.07.018|pmid=27555092|doi-access=free}}</ref> Mortality rates have decreased between the 1970s and 2000s.<ref>{{cite journal|last=Demain|first=JG|author2=Minaei, AA |author3=Tracy, JM|title=Anaphylaxis and insect allergy|journal=Current Opinion in Allergy and Clinical Immunology|date=August 2010|volume=10|issue=4|pages=318–22|pmid=20543675|doi=10.1097/ACI.0b013e32833a6c72|s2cid=12112811}}</ref> In Australia, death from food-induced anaphylaxis occur primarily in women while deaths due to insect bites primarily occur in males.<ref name=CEA11/> Death from anaphylaxis is most commonly triggered by medications.<ref name=CEA11/>