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====Norepinephrine==== Similar to dopamine, amphetamine dose-dependently increases the level of synaptic norepinephrine, the direct precursor of [[epinephrine]]. Amphetamine is believed to affect norepinephrine analogously to dopamine.<ref name="handbook2022_DAT" /><ref name="2020_Reith" /><ref name="2022 T1 LDX" /> In other words, amphetamine induces competitive {{abbr|NET|norepinephrine transporter}} reuptake inhibition, non-competitive reuptake inhibition and efflux at phosphorylated NET via PKC activation, CAMKIIα-mediated NET efflux without internalization, and norepinephrine release from {{abbr|VMAT2|vesicular monoamine transporter 2}}.<ref name="handbook2022_DAT" /><ref name="2020_Reith" /><ref name="2022 T1 LDX" />
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