Editing Epigenetics (section)

===Histone variants===
Different [[histone variants]] are incorporated into specific regions of the genome non-randomly. Their differential biochemical characteristics can affect genome functions via their roles in gene regulation,<ref>{{cite journal | vauthors = Buschbeck M, Hake SB | title = Variants of core histones and their roles in cell fate decisions, development and cancer | journal = Nature Reviews. Molecular Cell Biology | volume = 18 | issue = 5 | pages = 299–314 | date = May 2017 | pmid = 28144029 | doi = 10.1038/nrm.2016.166 | url = https://www.nature.com/articles/nrm.2016.166 | s2cid = 3307731 }}</ref> and maintenance of chromosome structures.<ref>{{cite journal | vauthors = Jang CW, Shibata Y, Starmer J, Yee D, Magnuson T | title = Histone H3.3 maintains genome integrity during mammalian development | journal = Genes & Development | volume = 29 | issue = 13 | pages = 1377–92 | date = July 2015 | pmid = 26159997 | pmc = 4511213 | doi = 10.1101/gad.264150.115 }}</ref>