Editing Androgen insensitivity syndrome (section)

===Testicular feminization===
In 1953, American [[gynecologist]] [[John McLean Morris|John Morris]] provided the first full description of what he called "testicular feminization syndrome" based on 82 cases compiled from the medical literature, including two of his own patients.<ref name="2006 hughes 20" /><ref name="1995 quigley 16" /><ref name="1953 morris 65" />  The term "testicular feminization" was coined to reflect Morris' observation that the testicles in these patients produced a hormone that had a feminizing effect on the body, a phenomenon now understood to be due to the inaction of androgens, and subsequent [[aromatization]] of testosterone into estrogen.<ref name="2006 hughes 20" />   A few years before Morris published his landmark paper, [[Lawson Wilkins]] had shown through experiment that unresponsiveness of the target cell to the action of androgenic hormones was a cause of "male pseudohermaphroditism".<ref name="1987 perez-palacios 27" /><ref name="1950 wilkins" />   Wilkins' work, which clearly demonstrated the lack of a therapeutic effect when [[46,XY]] patients were treated with androgens, caused a gradual shift in nomenclature from "testicular feminization" to "androgen resistance".<ref name="2008 oakes 21" />