Editing Sugar substitute (section)

===Obesity===
There is little evidence that artificial sweeteners directly affect the onset and mechanisms of [[obesity]], although consuming sweetened products is associated with weight gain in children.<ref name="brown">{{cite journal | last1=Brown | first1=Rebecca J. | last2=de Banate | first2=Mary Ann | last3=Rother | first3=Kristina I. | title=Artificial Sweeteners: A systematic review of metabolic effects in youth | journal=International Journal of Pediatric Obesity | volume=5 | issue=4 | year=2010 | issn=1747-7166 | pmid=20078374 | pmc=2951976 | doi=10.3109/17477160903497027 | pages=305–312}}</ref><ref name="young">{{cite journal | last1=Young | first1=Jordan | last2=Conway | first2=Ellen M. | last3=Rother | first3=Kristina I. | last4=Sylvetsky | first4=Allison C. | title=Low-calorie sweetener use, weight, and metabolic health among children: A mini-review | journal=Pediatric Obesity | volume=14 | issue=8 | date=2019-04-14 | pages=e12521 | issn=2047-6302 | pmid=30983091 | doi=10.1111/ijpo.12521 | s2cid=115206999 }}</ref> Some preliminary studies indicate that consumption of products manufactured with artificial sweeteners is associated with obesity and [[metabolic syndrome]], decreased [[satiety]], disturbed glucose [[metabolism]], and weight gain, mainly due to increased overall calorie intake, although the numerous factors influencing obesity remain poorly studied, as of 2021.<ref name=brown/><ref name=young/><ref>{{Cite journal |last1=Pearlman |first1=Michelle |last2=Obert |first2=Jon |last3=Casey |first3=Lisa |name-list-style=amp |date=December 2017 |title=The association between artificial sweeteners and obesity |url=http://link.springer.com/10.1007/s11894-017-0602-9 |url-status=live |journal=Current Gastroenterology Reports |language=en |volume=19 |issue=12 |pages=64 |doi=10.1007/s11894-017-0602-9 |issn=1522-8037 |pmid=29159583 |s2cid=46270291 |archive-url=https://web.archive.org/web/20230423112917/https://link.springer.com/article/10.1007/s11894-017-0602-9 |archive-date=23 April 2023 |access-date=22 September 2022}}</ref><ref>{{Cite journal |last=Christofides |first=Elena A. |date=October 2021 |title=Artificial sweeteners and obesity—Not the solution and potentially a problem |url=https://linkinghub.elsevier.com/retrieve/pii/S1530891X21011575 |journal=Endocrine Practice |language=en |volume=27 |issue=10 |pages=1052–1055 |doi=10.1016/j.eprac.2021.08.001 |pmid=34389515 |s2cid=237009397 |access-date=22 September 2022 |archive-date=27 November 2022 |archive-url=https://web.archive.org/web/20221127161625/https://linkinghub.elsevier.com/retrieve/pii/S1530891X21011575 |url-status=live }}</ref>