Editing Marburg virus disease (section)

=== 2021 Guinean cases ===
{{Main|2021 Guinea Marburg virus disease outbreak}}

In August 2021, two months after the re-emergent Ebola epidemic in the [[Guéckédou]] prefecture was declared over, a case of the Marburg disease was confirmed by health authorities through laboratory analysis.<ref name="mvdwho" /> Other potential case of the disease in a contact awaits official results. This was the first case of the Marburg hemorrhagic fever confirmed to happen in West Africa. The case of Marburg also has been identified in [[Guéckédou Prefecture|Guéckédou]].<ref name="reuters" /> During the outbreak, a total of one confirmed case, who died ([[Case fatality rate|CFR]]=100%), and 173 contacts were identified, including 14 high-risk contacts based on exposure.<ref name=":0">{{Cite web |title=Marburg virus disease - Guinea |url=https://www.who.int/emergencies/disease-outbreak-news/item/marburg-virus-disease---guinea |url-status=live |archive-url=https://web.archive.org/web/20221128214025/https://www.who.int/emergencies/disease-outbreak-news/item/marburg-virus-disease---guinea |archive-date=2022-11-28 |access-date=2022-11-29 |website=www.who.int |language=en}}</ref> Among them, 172 were followed for a period of 21 days, of which none developed symptoms. One high-risk contact was lost to follow up.<ref name=":0" /> Sequencing of an isolate from the Guinean patient showed that this outbreak was caused by the Angola-like Marburg virus.<ref>{{Cite journal |last=Koundouno |first=Fara R. |last2=Kafetzopoulou |first2=Liana E. |last3=Faye |first3=Martin |last4=Renevey |first4=Annick |last5=Soropogui |first5=Barrè |last6=Ifono |first6=Kékoura |last7=Nelson |first7=Emily V. |last8=Kamano |first8=Aly A. |last9=Tolno |first9=Charles |last10=Annibaldis |first10=Giuditta |last11=Millimono |first11=Saa L. |last12=Camara |first12=Jacob |last13=Kourouma |first13=Karifa |last14=Doré |first14=Ahmadou |last15=Millimouno |first15=Tamba E. |date=2022-06-30 |title=Detection of Marburg Virus Disease in Guinea |journal=New England Journal of Medicine |language=en |volume=386 |issue=26 |pages=2528–2530 |doi=10.1056/NEJMc2120183 |issn=0028-4793 |pmc=7613962 |pmid=35767445 |s2cid=250114159}}</ref> A colony of [[Egyptian fruit bat|Egyptian rousettus bats]] ([[Natural reservoir|reservoir host]] of [[Marburg virus]]) was found in close proximity (4.5&nbsp;km) to the village, where the Marburg virus disease outbreak emerged in 2021.<ref name=":1">{{Cite bioRxiv |biorxiv=10.1101/2022.11.03.514981v1 |first=Marat |last=Makenov |first2=Sanaba |last2=Boumbaly |title=Investigating the Zoonotic Origin of the Marburg Virus Outbreak in Guinea in 2021 |date=2022-11-04 |language=en |last3=Tolno |first3=Faya Raphael |last4=Sacko |first4=Nouminy |last5=N'Fatoma |first5=Leno Tamba |last6=Mansare |first6=Oumar |last7=Kolie |first7=Bonaventure |last8=Stukolova |first8=Olga |last9=Morozkin |first9=Evgeny |last10=Kholodilov |first10=Ivan |last11=Zhurenkova |first11=Olga |last12=Fyodorova |first12=Marina |last13=Akimkin |first13=Vasily |last14=Popova |first14=Anna |last15=Conde |first15=Namoudou}}</ref> Two sampled fruit bats from this colony were PCR-positive on the Marburg virus.<ref name=":1" />