Editing Vitamin C (section)

===Sepsis===
People in [[sepsis]] may have micronutrient deficiencies, including low levels of vitamin C.<ref name="pmid29984680">{{cite journal | vauthors = Belsky JB, Wira CR, Jacob V, Sather JE, Lee PJ | title = A review of micronutrients in sepsis: the role of thiamine, L-carnitine, vitamin C, selenium and vitamin D | journal = Nutrition Research Reviews | volume = 31 | issue = 2 | pages = 281–90 | date = December 2018 | pmid = 29984680 | doi = 10.1017/S0954422418000124 | s2cid = 51599526 }}</ref> An intravenous intake of doses much higher than the RDA, such as {{val|3|u=g/day}} or more, appears to be needed to maintain normal plasma concentrations in people with sepsis, as the body's demand for vitamin C may increase significantly due to the heightened inflammatory response and oxidative stress.<ref name="pmid30452091">{{cite journal |vauthors=Langlois PL, Manzanares W, Adhikari NK, Lamontagne F, Stoppe C, Hill A, Heyland DK |title=Vitamin C Administration to the Critically Ill: A Systematic Review and Meta-Analysis |journal=JPEN J Parenter Enteral Nutr |volume=43 |issue=3 |pages=335–346 |date=March 2019 |pmid=30452091 |doi=10.1002/jpen.1471 |url=}}</ref><ref name=Liang2023/><ref name="pmid25635594">{{cite journal |vauthors=Berger MM, Oudemans-van Straaten HM |title=Vitamin C supplementation in the critically ill patient |journal=Curr Opin Clin Nutr Metab Care |volume=18 |issue=2 |pages=193–201 |date=March 2015 |pmid=25635594 |doi=10.1097/MCO.0000000000000148 |s2cid=37895257 |url=}}</ref> Sepsis mortality may be reduced with administration of intravenous vitamin C.<ref name="pmid37111066">{{cite journal |vauthors=Xu C, Yi T, Tan S, Xu H, Hu Y, Ma J, Xu J |title=Association of oral or intravenous vitamin C supplementation with mortality: A systematic review and meta-analysis |journal=Nutrients |volume=15 |issue=8 |date=April 2023 |page=1848 |pmid=37111066 |pmc=10146309 |doi=10.3390/nu15081848 |doi-access=free |url=}}</ref><ref name="pmid37599680">{{cite journal |vauthors=Liang H, Mu Q, Sun W, Liu L, Qiu S, Xu Z, Cui Y, Yan Y, Sun T |title=Effect of intravenous vitamin C on adult septic patients: a systematic review and meta-analysis |journal=Front Nutr |volume=10 |issue= |pages=1211194 |date=2023 |pmid=37599680 |pmc=10437115 |doi=10.3389/fnut.2023.1211194 |doi-access=free |url=}}</ref>