Editing Paracetamol (section)

==Veterinary use==
[[File:Brown tree snake aerial bait cartridges.jpg|thumb|Brown tree snake aerial bait cartridges consisting of dead mice with 80{{nbsp}}mg paracetamol tablets]]

===Cats===
Paracetamol is extremely toxic to cats, which lack the necessary [[UGT1A6]] enzyme to detoxify it. Initial symptoms include vomiting, salivation, and discoloration of the tongue and gums. Unlike an overdose in humans, liver damage is rarely the cause of death; instead, [[methemoglobin]] formation and the production of [[Heinz bodies]] in red blood cells inhibit oxygen transport by the blood, causing [[asphyxiation]] ([[methemoglobinemia]] and [[hemolytic anemia]]).<ref name="CanVetJ2003-Allen">{{cite journal |vauthors = Allen AL |title = The diagnosis of acetaminophen toxicosis in a cat |journal = The Canadian Veterinary Journal |volume = 44 |issue = 6 |pages = 509–10 |date = June 2003 |pmid = 12839249 |pmc = 340185 }}</ref> Treatment of the toxicosis with [[acetylcysteine]] is recommended.<ref name="Richardson_2000" />

===Dogs===
Paracetamol has been reported to be as effective as aspirin in the treatment of musculoskeletal pain in dogs.<ref name=smallani>{{cite book|title=Small Animal Clinical Pharmacology |vauthors = Maddison JE, Page SW, Church D |publisher=Elsevier Health Sciences|year=2002|isbn=978-0702025730|pages=260–1 }}</ref> A paracetamol–codeine product (brand name Pardale-V)<ref name="Pardale">{{cite web|title = Pardale-V Oral Tablets |work = NOAH Compendium of Data Sheets for Animal Medicines |publisher = The National Office of Animal Health (NOAH) |date=11 November 2010|access-date = 20 January 2011| url = http://www.noahcompendium.co.uk/Dechra_Veterinary_Products/documents/S3428.html| archive-url = https://web.archive.org/web/20081122104413/http://www.noahcompendium.co.uk/Dechra_Veterinary_Products/documents/S3428.html| url-status=dead| archive-date = 22 November 2008}}</ref> licensed for use in dogs is available for purchase under supervision of a vet, pharmacist or other qualified person.<ref name="Pardale" /> It should be administered to dogs only on veterinary advice and with extreme caution.<ref name="Pardale" />

The main effect of toxicity in dogs is liver damage, and GI ulceration has been reported.<ref name="Richardson_2000">{{cite journal |title=Management of acetaminophen and ibuprofen toxicoses in dogs and cats |vauthors=Richardson JA |journal=Journal of Veterinary Emergency and Critical Care |volume=10 |issue=4 |pages=285–291 |year=2000 |doi=10.1111/j.1476-4431.2000.tb00013.x |url=http://www.aspcapro.org/mydocuments/c-veccs_july00.pdf |url-status=dead |archive-date=1 April 2010 |archive-url= https://web.archive.org/web/20100401014830/http://www.aspcapro.org/mydocuments/c-veccs_july00.pdf}}</ref><ref name="VetHumToxicol1998-Villar">{{cite journal |vauthors=Villar D, Buck WB, Gonzalez JM |title=Ibuprofen, aspirin and acetaminophen toxicosis and treatment in dogs and cats |journal = Veterinary and Human Toxicology |volume=40 |issue=3 |pages=156–62 |date=June 1998 |pmid=9610496}}</ref><ref>{{cite journal |vauthors=Gwaltney-Brant S, Meadows I |title=The 10 Most Common Toxicoses in Dogs |journal=Veterinary Medicine |pages=142–148 |date=March 2006 |url= http://veterinarymedicine.dvm360.com/toxicology-brief-10-most-common-toxicoses-dogs |url-status=dead |archive-url= https://web.archive.org/web/20110710160759/http://veterinarymedicine.dvm360.com/vetmed/Medicine/ArticleStandard/Article/detail/314007 |archive-date=10 July 2011 |access-date=28 October 2019}}</ref><ref>{{cite journal |vauthors=Dunayer E |title=Ibuprofen toxicosis in dogs, cats, and ferrets |journal=Veterinary Medicine |pages=580–586 |year=2004 |url=http://veterinarymedicine.dvm360.com/vetmed/Medicine/ArticleStandard/Article/detail/651048|url-status=live|archive-url=https://web.archive.org/web/20110710160815/http://veterinarymedicine.dvm360.com/vetmed/Medicine/ArticleStandard/Article/detail/651048 |archive-date=10 July 2011}}</ref> Acetylcysteine treatment is efficacious in dogs when administered within two hours of paracetamol ingestion.<ref name="Richardson_2000"/><ref name=smallani/>

===Snakes===
Paracetamol is lethal to snakes<ref>{{cite journal |vauthors=van den Hurk P, Kerkkamp HM |title=Phylogenetic origins for severe acetaminophen toxicity in snake species compared to other vertebrate taxa |year=2019 |journal=Comp Biochem Physiol C  |volume=215 |pages=18–24 |pmid=30268769 |doi=10.1016/j.cbpc.2018.09.003|s2cid=52890371 |url=https://tigerprints.clemson.edu/cgi/viewcontent.cgi?article=1115&context=bio_pubs }}</ref> and has been suggested as a chemical control program for the invasive [[brown tree snake]] (''Boiga irregularis'') in [[Guam]].<ref>{{cite journal |vauthors=Johnston J, Savarie P, Primus T, Eisemann J, Hurley J, Kohler D |title=Risk assessment of an acetaminophen baiting program for chemical control of brown tree snakes on Guam: evaluation of baits, snake residues, and potential primary and secondary hazards |year=2002 |journal=Environ Sci Technol |volume=36 |issue=17 |pages=3827–3833 |pmid=12322757 |doi=10.1021/es015873n |bibcode=2002EnST...36.3827J}}</ref><ref>{{cite news |url=http://news.blogs.cnn.com/2010/09/07/tylenol-loaded-mice-dropped-from-air-to-control-snakes/|title=Tylenol-loaded mice dropped from air to control snakes |vauthors = Lendon B |work=CNN|date=7 September 2010|access-date=7 September 2010| url-status=dead |archive-url=https://web.archive.org/web/20100909031539/http://news.blogs.cnn.com/2010/09/07/tylenol-loaded-mice-dropped-from-air-to-control-snakes/|archive-date=9 September 2010 }}</ref> Doses of 80{{nbsp}}mg are inserted into dead mice that are scattered by helicopter<ref>{{cite magazine |url=https://www.the-scientist.com/notebook/its-raining-mice-41065 |title=It's Raining Mice |vauthors=Richards S |date=1 May 2012 |magazine=The Scientist |url-status=live |archive-url=https://web.archive.org/web/20120515060208/http://the-scientist.com/2012/05/01/its-raining-mice/ |archive-date=15 May 2012}}</ref> as lethal bait to be consumed by the snakes.