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==== Methadone clinics ==== In the United States, prescription of methadone requires intensive monitoring and must be obtained in-person from an Opioid Treatment Program—colloquially known as a 'methadone clinic'—when prescribed for [[opioid use disorder]] (OUD).<ref name="Anderson_2000"/> According to federal laws, methadone cannot be prescribed by a doctor and obtained from a pharmacy to treat addiction. Because of its long half-life, methadone is almost invariably prescribed to be taken in a single daily dose. At nearly all methadone clinics in the US, patients must visit a clinic to receive and take their dose under the supervision of a nurse. Both patients who are new to methadone treatment and high-risk patients—such as those who are using drugs and alcohol, including cannabis in some states—must visit the clinic daily.<ref>{{cite web|title=Methadone|url=https://www.samhsa.gov/medication-assisted-treatment/medications-counseling-related-conditions/methadone|access-date=15 February 2021|website=www.samhsa.gov|date=16 June 2015 |language=en}}</ref><ref>{{cite web|title=42 CFR § 8.12 – Federal opioid treatment standards.|url=https://www.law.cornell.edu/cfr/text/42/8.12|access-date=15 February 2021|website=LII / Legal Information Institute|language=en}}</ref>
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