Editing Macrophage (section)

==== Tuberculosis ====
Once engulfed by a macrophage, the causative agent of tuberculosis, ''Mycobacterium tuberculosis'',<ref name="Sherris">{{cite book|title=Sherris Medical Microbiology|publisher=McGraw Hill|year=2004|isbn=978-0-8385-8529-0|veditors=Ryan KJ, Ray CG|edition=4th}}</ref> avoids cellular defenses and uses the cell to replicate. Recent evidence suggests that in response to the pulmonary infection of ''Mycobacterium tuberculosis'', the peripheral macrophages matures into M1 phenotype. Macrophage M1 phenotype is characterized by increased secretion of pro-inflammatory cytokines (IL-1β, TNF-α, and IL-6) and increased glycolytic activities essential for clearance of infection.<ref name="NIX-mediated mitophagy regulate met"/>