Editing Diarrhea (section)

===Vaccination===
Immunization against the pathogens that cause diarrheal disease is a viable prevention strategy, however it does require targeting certain pathogens for vaccination. In the case of Rotavirus, which was responsible for around 6% of diarrheal episodes and 20% of diarrheal disease deaths in the children of developing countries, use of a Rotavirus vaccine in trials in 1985 yielded a slight (2–3%) decrease in total diarrheal disease incidence, while reducing overall mortality by 6–10%. Similarly, a Cholera vaccine showed a strong reduction in morbidity and mortality, though the overall impact of vaccination was minimal as Cholera is not one of the major causative pathogens of diarrheal disease.<ref>{{cite journal | vauthors = de Zoysa I, Feachem RG | title = Interventions for the control of diarrhoeal diseases among young children: rotavirus and cholera immunization | journal = Bulletin of the World Health Organization | volume = 63 | issue = 3 | pages = 569–83 | year = 1985 | pmid = 3876173 | pmc = 2536413 }}</ref> Since this time, more effective vaccines have been developed that have the potential to save many thousands of lives in developing nations, while reducing the overall cost of treatment, and the costs to society.<ref>{{cite journal | vauthors = Rheingans RD, Antil L, Dreibelbis R, Podewils LJ, Bresee JS, Parashar UD | title = Economic costs of rotavirus gastroenteritis and cost-effectiveness of vaccination in developing countries | journal = The Journal of Infectious Diseases | volume = 200 | pages = S16-27 | date = November 2009 | issue = Suppl 1 | pmid = 19817595 | doi = 10.1086/605026 | doi-access = free | url = http://libres.uncg.edu/ir/asu/f/Rheingans_Richard_2009_Economic_Costs_of_Rotavirus_orig.pdf | access-date = 27 February 2024 | archive-date = 27 February 2024 | archive-url = https://web.archive.org/web/20240227043727/http://libres.uncg.edu/ir/asu/f/Rheingans_Richard_2009_Economic_Costs_of_Rotavirus_orig.pdf | url-status = live }}</ref><ref>{{cite book|title=Oral cholera vaccines in mass immunization campaigns |year=2010 |publisher=WHO |isbn=978-92-4-150043-2 |pages=6–8 |url= http://whqlibdoc.who.int/publications/2010/9789241500432_eng.pdf |url-status=live |archive-url= https://web.archive.org/web/20140903045312/http://whqlibdoc.who.int/publications/2010/9789241500432_eng.pdf |archive-date=3 September 2014 }}</ref>

[[Rotavirus vaccine]] decreases the rates of diarrhea in a population.<ref name=WHO2010a/><ref>{{cite journal | vauthors = Soares-Weiser K, Goldberg E, Tamimi G, Pitan OC, Leibovici L | title = Rotavirus vaccine for preventing diarrhoea | journal = The Cochrane Database of Systematic Reviews | issue = 1 | pages = CD002848 | date = 2004-01-26 | volume = 2004 | pmid = 14973994 | pmc = 6532746 | doi = 10.1002/14651858.CD002848.pub2  | collaboration = Cochrane Infectious Diseases Group }}</ref> New vaccines against rotavirus, ''Shigella'', [[Enterotoxigenic Escherichia coli|Enterotoxigenic Escherichia coli (ETEC)]], and cholera are under development, as well as other causes of infectious diarrhea.{{medcn|date=January 2015}}