Editing Brain tumor (section)

===Glioblastoma===
{{Main|Glioblastoma}}

[[Glioblastoma]] is the most aggressive ([[grading of the tumors of the central nervous system|grade 4]]) and most common form of a malignant primary brain tumor. Even when aggressive multimodality therapy consisting of radiotherapy, chemotherapy, and surgical excision is used, median survival is only 15–18 months.<ref name=":12" /> Standard therapy for glioblastoma consists of maximal surgical [[Segmental resection|resection]] of the tumor, followed by radiotherapy between two and four weeks after the [[craniotomy|surgical procedure]] to remove the cancer, then by [[temozolomide|chemotherapy]], such as [[temozolomide]].<ref name=":2">{{cite journal | vauthors = Sasmita AO, Wong YP, Ling AP | title = Biomarkers and therapeutic advances in glioblastoma multiforme | journal = Asia-Pacific Journal of Clinical Oncology | volume = 14 | issue = 1 | pages = 40–51 | date = February 2018 | pmid = 28840962 | doi = 10.1111/ajco.12756 | doi-access = free }}</ref> Most patients with glioblastoma take a [[corticosteroid]], typically [[dexamethasone]], during their illness to relieve symptoms. Experimental treatments include [[targeted therapy]], [[radiosurgery#Gamma Knife|gamma knife radiosurgery]],<ref>
{{cite web |url=http://brain.mgh.harvard.edu/patientguide.htm |title=GBM Guide – MGH Brain Tumor Center |publisher=Brain.mgh.harvard.edu |access-date=17 February 2012 |url-status=live |archive-url=https://web.archive.org/web/20120216012258/http://brain.mgh.harvard.edu/PatientGuide.htm |archive-date=16 February 2012  }}
</ref> [[boron neutron capture therapy]], [[gene therapy]], and [[Carmustine#Implants|chemowafer implants]].<ref>{{cite journal |last1=Tai |first1=Chien-Kuo |last2=Kasahara |first2=Noriyuki |title=Replication-competent retrovirus vectors for cancer gene therapy |journal=Frontiers in Bioscience |date=January 2008 |volume=13 |issue=13 |pages=3083–3095 |doi=10.2741/2910 |pmid=17981778 }}</ref><ref>{{cite journal | vauthors = Murphy AM, Rabkin SD | title = Current status of gene therapy for brain tumors | journal = Translational Research | volume = 161 | issue = 4 | pages = 339–54 | date = April 2013 | pmid = 23246627 | pmc = 3733107 | doi = 10.1016/j.trsl.2012.11.003 }}</ref>