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===Muscular action potentials=== {{Main|Neuromuscular junction|Muscle contraction}} The action potential in a normal skeletal muscle cell is similar to the action potential in neurons.{{sfn|Ganong|1991|pp=59β60}} Action potentials result from the depolarization of the cell membrane (the [[sarcolemma]]), which opens voltage-sensitive sodium channels; these become inactivated and the membrane is repolarized through the outward current of potassium ions. The resting potential prior to the action potential is typically β90mV, somewhat more negative than typical neurons. The muscle action potential lasts roughly 2β4 ms, the absolute refractory period is roughly 1β3 ms, and the conduction velocity along the muscle is roughly 5 m/s. The action potential releases [[calcium]] ions that free up the [[tropomyosin]] and allow the muscle to contract. Muscle action potentials are provoked by the arrival of a pre-synaptic neuronal action potential at the [[neuromuscular junction]], which is a common target for [[neurotoxin]]s.<ref name=Newmark group=lower-alpha />
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