Editing Hippocampus (section)

===Transient global amnesia===

[[Transient global amnesia]] is a dramatic, sudden, temporary, near-total loss of short-term memory. Various causes have been hypothesized including ischemia, epilepsy, migraine<ref name="Szabo">{{cite book | vauthors = Szabo K | title = The Hippocampus in Clinical Neuroscience | chapter = Transient global amnesia | series = Frontiers of Neurology and Neuroscience | year = 2014 | volume = 34 | issue = 5633 | pages = 143–149 | doi = 10.1159/000356431 | pmid = 24777137 | isbn = 978-3-318-02567-5 | chapter-url = http://www.bmj.com/cgi/content/short/4/5633/723-a | access-date = 2018-08-15 | archive-date = 2021-09-23 | archive-url = https://web.archive.org/web/20210923091233/https://www.bmj.com/content/4/5633/723.2 | url-status = live }}</ref> and disturbance of cerebral venous blood flow,<ref>{{cite journal | vauthors = Lewis SL | title = Aetiology of transient global amnesia | journal = Lancet | volume = 352 | issue = 9125 | pages = 397–399 | date = August 1998 | pmid = 9717945 | doi = 10.1016/S0140-6736(98)01442-1 | s2cid = 12779088 }}</ref> leading to [[ischemia]] of structures such as the hippocampus that are involved in memory.<ref>{{cite journal | vauthors = Chung CP, Hsu HY, Chao AC, Chang FC, Sheng WY, Hu HH | title = Detection of intracranial venous reflux in patients of transient global amnesia | journal = Neurology | volume = 66 | issue = 12 | pages = 1873–1877 | date = June 2006 | pmid = 16801653 | doi = 10.1212/01.wnl.0000219620.69618.9d | s2cid = 39724390 }}</ref>

There has been no scientific proof of any cause. However, [[diffusion-weighted MRI]] studies taken from 12 to 24 hours following an episode has shown there to be small dot-like lesions in the hippocampus. These findings have suggested a possible implication of CA1 neurons made vulnerable by metabolic stress.<ref name=Szabo/>