Editing Genomics (section)

=== Genomic medicine ===
Next-generation genomic technologies allow clinicians and biomedical researchers to drastically increase the amount of genomic data collected on large study populations.<ref name = "Feero_2011"/> When combined with new informatics approaches that integrate many kinds of data with genomic data in disease research, this allows researchers to better understand the genetic bases of drug response and disease.<ref name = "Feero_2011a"/><ref name = "Lu_2014"/>

Early efforts to apply the genome to medicine included those by a Stanford team led by [[Euan Ashley]] who developed the first tools for the medical interpretation of a human genome.<ref name="Ashley_2010" /><ref name="Dewey_2011" /><ref name="Dewey_2014" /> The Genomes2People research program at [[Brigham and Women’s Hospital]], [[Broad Institute]] and Harvard Medical School was established in 2012 to conduct empirical research in translating genomics into health. [[Brigham and Women's Hospital]] opened a Preventive Genomics Clinic in August 2019, with [[Massachusetts General Hospital]] following a month later.<ref name="Robbins_2019" /><ref name="Dark_Daily_2020" /> The ''All of Us'' research program aims to collect genome sequence data from 1 million participants to become a critical component of the precision medicine research platform<ref name="NIH_2018" /> and the ''UK Biobank'' initiative has studied more than 500.000 individuals with deep genomic and phenotypic data.<ref>{{Cite journal |last1=Bycroft |first1=Clare |last2=Freeman |first2=Colin |last3=Petkova |first3=Desislava |last4=Band |first4=Gavin |last5=Elliott |first5=Lloyd T. |last6=Sharp |first6=Kevin |last7=Motyer |first7=Allan |last8=Vukcevic |first8=Damjan |last9=Delaneau |first9=Olivier |last10=O'Connell |first10=Jared |last11=Cortes |first11=Adrian |last12=Welsh |first12=Samantha |last13=Young |first13=Alan |last14=Effingham |first14=Mark |last15=McVean |first15=Gil |date=October 2018 |title=The UK Biobank resource with deep phenotyping and genomic data |journal=Nature |volume=562 |issue=7726 |pages=203–209 |doi=10.1038/s41586-018-0579-z |issn=1476-4687 |pmc=6786975 |pmid=30305743|bibcode=2018Natur.562..203B }}</ref>