Editing Carbon monoxide (section)

====Medicine====
{{Main|Carbon monoxide-releasing molecules}}

Studies involving carbon monoxide have been conducted in many laboratories throughout the world for its anti-inflammatory and cytoprotective properties.<ref>{{Cite journal|last1=Motterlini|first1=Roberto|last2=Foresti|first2=Roberta|date=2017-01-11|title=Biological signaling by carbon monoxide and carbon monoxide-releasing molecules|journal=American Journal of Physiology. Cell Physiology|volume=312|issue=3|pages=C302–C313|doi=10.1152/ajpcell.00360.2016|pmid=28077358|issn=0363-6143|doi-access=free}}</ref> These properties have the potential to be used to prevent the development of a series of pathological conditions including ischemia reperfusion injury, transplant rejection, atherosclerosis, severe sepsis, severe malaria, or autoimmunity.<ref name="Motterlini-2010" /> Many pharmaceutical drug delivery initiatives have developed methods to safely administer carbon monoxide, and subsequent controlled clinical trials have evaluated the therapeutic effect of carbon monoxide.<ref>{{Cite journal|last1=Hopper|first1=Christopher P.|last2=Meinel|first2=Lorenz|last3=Steiger|first3=Christoph|last4=Otterbein|first4=Leo E.|date=2018-10-11|title=Where is the Clinical Breakthrough of Heme Oxygenase-1 / Carbon Monoxide Therapeutics?|url=https://www.eurekaselect.com/164002/article|journal=Current Pharmaceutical Design|language=en|volume=24|issue=20|pages=2264–2282|doi=10.2174/1381612824666180723161811|pmid=30039755|s2cid=51712930}}</ref>