Editing Sinusitis (section)

===Corticosteroids===
For unconfirmed acute sinusitis, [[Nasal spray#Corticosteroid|nasal sprays]] using [[corticosteroid]]s have not been found to be better than a [[placebo]] either alone or in combination with antibiotics.<ref>{{cite journal | vauthors = Williamson IG, Rumsby K, Benge S, Moore M, Smith PW, Cross M, Little P | title = Antibiotics and topical nasal steroid for treatment of acute maxillary sinusitis: a randomized controlled trial | journal = JAMA | volume = 298 | issue = 21 | pages = 2487–96 | date = December 2007 | pmid = 18056902 | doi = 10.1001/jama.298.21.2487 | doi-access =  }}</ref> For cases confirmed by radiology or nasal endoscopy, treatment with intranasal corticosteroids alone or in combination with antibiotics is supported.<ref>{{cite journal | vauthors = Zalmanovici Trestioreanu A, Yaphe J | title = Intranasal steroids for acute sinusitis | journal = The Cochrane Database of Systematic Reviews | volume = 12 | issue = 12 | pages = CD005149 | date = December 2013 | pmid = 24293353 | pmc = 6698484 | doi = 10.1002/14651858.CD005149.pub4 }}</ref> The benefit, however, is small.<ref>{{cite journal | vauthors = Hayward G, Heneghan C, Perera R, Thompson M | title = Intranasal corticosteroids in management of acute sinusitis: a systematic review and meta-analysis | journal = Annals of Family Medicine | volume = 10 | issue = 3 | pages = 241–9 | year = 2012 | pmid = 22585889 | pmc = 3354974 | doi = 10.1370/afm.1338 }}</ref>

For confirmed chronic rhinosinusitis, there is limited evidence that intranasal steroids improve symptoms and insufficient evidence that one type of steroid is more effective.<ref>{{cite journal | vauthors = Chong LY, Head K, Hopkins C, Philpott C, Schilder AG, Burton MJ | title = Intranasal steroids versus placebo or no intervention for chronic rhinosinusitis | journal = The Cochrane Database of Systematic Reviews | volume = 2016 | pages = CD011996 | date = April 2016 | issue = 4 | pmid = 27115217 | doi = 10.1002/14651858.cd011996.pub2 | pmc = 9393647 | s2cid = 205210710 | url = https://kclpure.kcl.ac.uk/portal/en/publications/intranasal-steroids-versus-placebo-or-no-intervention-for-chronic-rhinosinusitis(281bb1c8-9c9a-4d27-adde-37f93e7bf7fc).html | access-date = 2019-11-15 | archive-date = 2019-11-15 | archive-url = https://web.archive.org/web/20191115193627/https://kclpure.kcl.ac.uk/portal/en/publications/intranasal-steroids-versus-placebo-or-no-intervention-for-chronic-rhinosinusitis(281bb1c8-9c9a-4d27-adde-37f93e7bf7fc).html | url-status = live }}</ref><ref>{{cite journal | vauthors = Chong LY, Head K, Hopkins C, Philpott C, Burton MJ, Schilder AG | title = Different types of intranasal steroids for chronic rhinosinusitis | journal = The Cochrane Database of Systematic Reviews | volume = 2016 | pages = CD011993 | date = April 2016 | issue = 4 | pmid = 27115215 | doi = 10.1002/14651858.cd011993.pub2 | pmc = 8939045 | s2cid = 205210689 }}</ref>

There is only limited evidence to support short treatment with corticosteroids by mouth for chronic rhinosinusitis with nasal polyps.<ref>{{cite journal | vauthors = Head K, Chong LY, Hopkins C, Philpott C, Burton MJ, Schilder AG | title = Short-course oral steroids alone for chronic rhinosinusitis | journal = The Cochrane Database of Systematic Reviews | volume = 2016 | pages = CD011991 | date = April 2016 | issue = 4 | pmid = 27113367 | doi = 10.1002/14651858.cd011991.pub2 | pmc = 8504433 }}</ref><ref name="pmid17844873">{{cite journal | vauthors = Fokkens W, Lund V, Mullol J | title = European position paper on rhinosinusitis and nasal polyps 2007 | journal = Rhinology. Supplement | volume = 20 | issue = 1 | pages = 1–136 | year = 2007 | pmid = 17844873 | doi = 10.1017/S0959774306000060 | s2cid = 35987497 }}</ref><ref>{{cite journal | vauthors = Thomas M, Yawn BP, Price D, Lund V, Mullol J, Fokkens W | title = EPOS Primary Care Guidelines: European Position Paper on the Primary Care Diagnosis and Management of Rhinosinusitis and Nasal Polyps 2007 - a summary | journal = Primary Care Respiratory Journal | volume = 17 | issue = 2 | pages = 79–89 | date = June 2008 | pmid = 18438594 | pmc = 6619880 | doi = 10.3132/pcrj.2008.00029 }}</ref> There is limited evidence to support corticosteroids by mouth in combination with antibiotics for acute sinusitis; it has only short-term effect improving the symptoms.<ref>{{cite journal | vauthors = Venekamp RP, Thompson MJ, Hayward G, Heneghan CJ, Del Mar CB, Perera R, Glasziou PP, Rovers MM | title = Systemic corticosteroids for acute sinusitis | journal = The Cochrane Database of Systematic Reviews | issue = 3 | pages = CD008115 | date = March 2014 | pmid = 24664368 | doi = 10.1002/14651858.CD008115.pub3 | pmc = 11179165 | url = https://pure.bond.edu.au/ws/files/32844104/Systemic_corticosteroids_for_acute_sinusitis.pdf | access-date = 2019-11-15 | archive-date = 2019-11-15 | archive-url = https://web.archive.org/web/20191115193635/https://pure.bond.edu.au/ws/files/32844104/Systemic_corticosteroids_for_acute_sinusitis.pdf | url-status = live }}</ref><ref>{{cite journal | vauthors = Head K, Chong LY, Hopkins C, Philpott C, Schilder AG, Burton MJ | title = Short-course oral steroids as an adjunct therapy for chronic rhinosinusitis | journal = The Cochrane Database of Systematic Reviews | volume = 2016 | pages = CD011992 | date = April 2016 | issue = 4 | pmid = 27115214 | doi = 10.1002/14651858.cd011992.pub2 | pmc = 8763342 | s2cid = 205210682 }}</ref>