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== References == {{reflist|33em|refs= <!--not used <ref name="Assadi_2003">{{cite journal | vauthors = Assadi AH, Zhang G, Beffert U, McNeil RS, Renfro AL, Niu S, Quattrocchi CC, Antalffy BA, Sheldon M, Armstrong DD, Wynshaw-Boris A, Herz J, D'Arcangelo G, Clark GD | title = Interaction of reelin signaling and Lis1 in brain development | journal = [[Nature Genetics]] |volume= 35|issue= 3|pages= 270–6 |date=October 2003 | doi=10.1038/ng1257 | pmid=14578885}}</ref> --> <ref name="pmid20442744" >{{cite journal | vauthors = Holt R, Barnby G, Maestrini E, Bacchelli E, Brocklebank D, Sousa I, Mulder EJ, Kantojärvi K, Järvelä I, Klauck SM, Poustka F, Bailey AJ, Monaco AP | title = Linkage and candidate gene studies of autism spectrum disorders in European populations | journal = European Journal of Human Genetics | volume = 18 | issue = 9 | pages = 1013–9 | date = September 2010 | pmid = 20442744 | pmc = 2987412 | doi = 10.1038/ejhg.2010.69 }}</ref> <ref name="pmid19952965">{{cite journal | vauthors = Lintas C, Persico AM | title = Neocortical RELN promoter methylation increases significantly after puberty | journal = NeuroReport | volume = 21 | issue = 2 | pages = 114–8 | date = January 2010 | pmid = 19952965 | doi = 10.1097/WNR.0b013e328334b343 | s2cid = 206137259 }}</ref> <ref name="LTP1">{{cite journal | vauthors = Weeber EJ, Beffert U, Jones C, Christian JM, Forster E, Sweatt JD, Herz J | title = Reelin and ApoE receptors cooperate to enhance hippocampal synaptic plasticity and learning | journal = The Journal of Biological Chemistry | volume = 277 | issue = 42 | pages = 39944–52 | date = October 2002 | pmid = 12167620 | doi = 10.1074/jbc.M205147200 | doi-access = free }}</ref> <ref name="LTP2">{{cite journal | vauthors = D'Arcangelo G | title = Apoer2: a reelin receptor to remember | journal = Neuron | volume = 47 | issue = 4 | pages = 471–3 | date = August 2005 | pmid = 16102527 | doi = 10.1016/j.neuron.2005.08.001 | s2cid = 15091293 | doi-access = free }}</ref> <ref name="Niu_2004">{{cite journal | vauthors = Niu S, Renfro A, Quattrocchi CC, Sheldon M, D'Arcangelo G | title = Reelin promotes hippocampal dendrite development through the VLDLR/ApoER2-Dab1 pathway | journal = Neuron | volume = 41 | issue = 1 | pages = 71–84 | date = January 2004 | pmid = 14715136 | doi = 10.1016/S0896-6273(03)00819-5 | s2cid = 10716252 | doi-access = free }}</ref> <ref name="pmid18842893">{{cite journal | vauthors = Niu S, Yabut O, D'Arcangelo G | title = The Reelin signaling pathway promotes dendritic spine development in hippocampal neurons | journal = The Journal of Neuroscience | volume = 28 | issue = 41 | pages = 10339–48 | date = October 2008 | pmid = 18842893 | pmc = 2572775 | doi = 10.1523/JNEUROSCI.1917-08.2008 }}</ref> <ref name="Schizophrenia Research Forum: Current Hypotheses">{{cite web | url = http://www.schizophreniaforum.org/for/curr/grayson/default.asp | title = Current Hypotheses | vauthors = Grayson DR, Guidotti A, Costa E | date = 17 January 2008 | work = Schizophrenia Research Forum | publisher = schizophreniaforum.org | access-date = 23 August 2008 | url-status = dead | archive-url = https://web.archive.org/web/20080917064917/http://www.schizophreniaforum.org/for/curr/grayson/default.asp | archive-date = 17 September 2008 | df = dmy-all }}</ref> <ref name="pmid19395859">{{cite journal | vauthors = Grayson DR, Chen Y, Dong E, Kundakovic M, Guidotti A | title = From trans-methylation to cytosine methylation: evolution of the methylation hypothesis of schizophrenia | journal = Epigenetics | volume = 4 | issue = 3 | pages = 144–9 | date = April 2009 | pmid = 19395859 | doi = 10.4161/epi.4.3.8534 | doi-access = free }}</ref> <ref name="pmid17870056">{{cite journal | vauthors = Tochigi M, Iwamoto K, Bundo M, Komori A, Sasaki T, Kato N, Kato T | title = Methylation status of the reelin promoter region in the brain of schizophrenic patients | journal = Biological Psychiatry | volume = 63 | issue = 5 | pages = 530–3 | date = March 2008 | pmid = 17870056 | doi = 10.1016/j.biopsych.2007.07.003 | s2cid = 11816759 }}</ref> <ref name="pmid18319075">{{cite journal | vauthors = Mill J, Tang T, Kaminsky Z, Khare T, Yazdanpanah S, Bouchard L, Jia P, Assadzadeh A, Flanagan J, Schumacher A, Wang SC, Petronis A | title = Epigenomic profiling reveals DNA-methylation changes associated with major psychosis | journal = American Journal of Human Genetics | volume = 82 | issue = 3 | pages = 696–711 | date = March 2008 | pmid = 18319075 | pmc = 2427301 | doi = 10.1016/j.ajhg.2008.01.008 }}</ref> <ref name="falconer">{{Cite journal | vauthors = Falconer DS |date=January 1951 | title = Two new mutants, 'trembler' and 'reeler', with neurological actions in the house mouse (Mus musculus L.) | journal = Journal of Genetics | volume = 50 | issue = 2 | pages = 192–201 | doi = 10.1007/BF02996215 |pmid=24539699 |s2cid=37918631 | url = http://www.ias.ac.in/jarch/jgenet/50/192.pdf }}</ref> <ref name="pmid16769115">{{cite journal | vauthors = Tueting P, Doueiri MS, Guidotti A, Davis JM, Costa E | title = Reelin down-regulation in mice and psychosis endophenotypes | journal = Neuroscience and Biobehavioral Reviews | volume = 30 | issue = 8 | pages = 1065–77 | year = 2006 | pmid = 16769115 | doi = 10.1016/j.neubiorev.2006.04.001 | s2cid = 21156214 }}</ref> <ref name="hamburgh">{{cite journal | vauthors = Hamburgh M | journal = Developmental Biology | volume = 8 | issue = 2 | pages = 165–85 | date = October 1963 | pmid = 14069672 | doi = 10.1016/0012-1606(63)90040-X | title = Analysis of the postnatal developmental effects of "reeler," a neurological mutation in mice. A study in developmental genetics }}</ref> <ref name="caviness">{{cite journal | vauthors = Caviness VS | title = Patterns of cell and fiber distribution in the neocortex of the reeler mutant mouse | journal = The Journal of Comparative Neurology | volume = 170 | issue = 4 | pages = 435–47 | date = December 1976 | pmid = 1002868 | doi = 10.1002/cne.901700404 | s2cid = 34383977 }}</ref> <ref name="pmid7972007">{{cite journal | vauthors = Miao GG, Smeyne RJ, D'Arcangelo G, Copeland NG, Jenkins NA, Morgan JI, Curran T | title = Isolation of an allele of reeler by insertional mutagenesis | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 91 | issue = 23 | pages = 11050–4 | date = November 1994 | pmid = 7972007 | pmc = 45164 | doi = 10.1073/pnas.91.23.11050 | bibcode = 1994PNAS...9111050M | doi-access = free }}</ref> <ref name="Darcan1">{{cite journal | vauthors = D'Arcangelo G, Miao GG, Chen SC, Soares HD, Morgan JI, Curran T | title = A protein related to extracellular matrix proteins deleted in the mouse mutant reeler | journal = Nature | volume = 374 | issue = 6524 | pages = 719–23 | date = April 1995 | pmid = 7715726 | doi = 10.1038/374719a0 | bibcode = 1995Natur.374..719D | s2cid = 4266946 }}</ref> <ref name="cr50">{{cite journal | vauthors = Ogawa M, Miyata T, Nakajima K, Yagyu K, Seike M, Ikenaka K, Yamamoto H, Mikoshiba K | title = The reeler gene-associated antigen on Cajal-Retzius neurons is a crucial molecule for laminar organization of cortical neurons | journal = Neuron | volume = 14 | issue = 5 | pages = 899–912 | date = May 1995 | pmid = 7748558 | doi = 10.1016/0896-6273(95)90329-1 | s2cid = 17993812 | doi-access = free }}</ref> <ref name="pmid9837937">{{cite journal | vauthors = Trommsdorff M, Borg JP, Margolis B, Herz J | title = Interaction of cytosolic adaptor proteins with neuronal apolipoprotein E receptors and the amyloid precursor protein | journal = The Journal of Biological Chemistry | volume = 273 | issue = 50 | pages = 33556–60 | date = December 1998 | pmid = 9837937 | doi = 10.1074/jbc.273.50.33556 | doi-access = free }}</ref> <ref name="receptors_discovery">{{cite journal | vauthors = Trommsdorff M, Gotthardt M, Hiesberger T, Shelton J, Stockinger W, Nimpf J, Hammer RE, Richardson JA, Herz J | title = Reeler/Disabled-like disruption of neuronal migration in knockout mice lacking the VLDL receptor and ApoE receptor 2 | journal = Cell | volume = 97 | issue = 6 | pages = 689–701 | date = June 1999 | pmid = 10380922 | doi = 10.1016/S0092-8674(00)80782-5 | s2cid = 13492626 | doi-access = free }}</ref> <ref name="yotari_and_scrambler">{{cite journal | vauthors = Sheldon M, Rice DS, D'Arcangelo G, Yoneshima H, Nakajima K, Mikoshiba K, Howell BW, Cooper JA, Goldowitz D, Curran T | title = Scrambler and yotari disrupt the disabled gene and produce a reeler-like phenotype in mice | journal = Nature | volume = 389 | issue = 6652 | pages = 730–3 | date = October 1997 | pmid = 9338784 | doi = 10.1038/39601 | bibcode = 1997Natur.389..730S | s2cid = 4414738 }}</ref> <ref name="reelin_G_scholar_search_title">[https://scholar.google.com/scholar?as_q=reelin&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=title&as_sauthors=&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en&lr=&safe=off "Reelin" mentioned in the titles of scientific literature] – a search in the [[Google Scholar]]</ref> <ref name="Reelin_book_2008">{{cite book | editor = Hossein S. Fatemi | title = Reelin Glycoprotein: Structure, Biology and Roles in Health and Disease | publisher = Springer | year = 2008 | page = 444 | isbn = 978-0-387-76760-4 }}</ref> <ref name="golgi">{{cite journal | vauthors = Lacor PN, Grayson DR, Auta J, Sugaya I, Costa E, Guidotti A | title = Reelin secretion from glutamatergic neurons in culture is independent from neurotransmitter regulation | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 97 | issue = 7 | pages = 3556–61 | date = March 2000 | pmid = 10725375 | pmc = 16278 | doi = 10.1073/pnas.050589597 | bibcode = 2000PNAS...97.3556L | doi-access = free }}</ref> <ref name="cr_cells">{{cite journal | vauthors = Meyer G, Goffinet AM, Fairén A | title = What is a Cajal-Retzius cell? A reassessment of a classical cell type based on recent observations in the developing neocortex | journal = Cerebral Cortex | volume = 9 | issue = 8 | pages = 765–75 | date = December 1999 | pmid = 10600995 | doi = 10.1093/cercor/9.8.765 | doi-access = }}</ref> <ref name="pmid9671277">{{cite journal | vauthors = Meyer G, Goffinet AM | title = Prenatal development of reelin-immunoreactive neurons in the human neocortex | journal = The Journal of Comparative Neurology | volume = 397 | issue = 1 | pages = 29–40 | date = July 1998 | pmid = 9671277 | doi = 10.1002/(SICI)1096-9861(19980720)397:1<29::AID-CNE3>3.3.CO;2-7 }}</ref> <ref name="Schiffmann">{{cite journal | vauthors = Schiffmann SN, Bernier B, Goffinet AM | title = Reelin mRNA expression during mouse brain development | journal = The European Journal of Neuroscience | volume = 9 | issue = 5 | pages = 1055–71 | date = May 1997 | pmid = 9182958 | doi = 10.1111/j.1460-9568.1997.tb01456.x | s2cid = 22576790 }}</ref> <ref name="Interneurons">{{cite journal | vauthors = Pesold C, Impagnatiello F, Pisu MG, Uzunov DP, Costa E, Guidotti A, Caruncho HJ | title = Reelin is preferentially expressed in neurons synthesizing gamma-aminobutyric acid in cortex and hippocampus of adult rats | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 95 | issue = 6 | pages = 3221–6 | date = March 1998 | pmid = 9501244 | pmc = 19723 | doi = 10.1073/pnas.95.6.3221 | bibcode = 1998PNAS...95.3221P | doi-access = free }}</ref> <ref name="Regional_patterns_1998">{{cite journal | vauthors = Alcántara S, Ruiz M, D'Arcangelo G, Ezan F, de Lecea L, Curran T, Sotelo C, Soriano E | title = Regional and cellular patterns of reelin mRNA expression in the forebrain of the developing and adult mouse | journal = The Journal of Neuroscience | volume = 18 | issue = 19 | pages = 7779–99 | date = October 1998 | pmid = 9742148 | pmc = 6792998 | doi = 10.1523/JNEUROSCI.18-19-07779.1998 }}</ref> <ref name="No_parvalbumin_1999">{{cite journal | vauthors = Pesold C, Liu WS, Guidotti A, Costa E, Caruncho HJ | title = Cortical bitufted, horizontal, and Martinotti cells preferentially express and secrete reelin into perineuronal nets, nonsynaptically modulating gene expression | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 96 | issue = 6 | pages = 3217–22 | date = March 1999 | pmid = 10077664 | pmc = 15922 | doi = 10.1073/pnas.96.6.3217 | bibcode = 1999PNAS...96.3217P | doi-access = free }}</ref> <ref name="pmid19543540">{{cite journal | vauthors = Suárez-Solá ML, González-Delgado FJ, Pueyo-Morlans M, Medina-Bolívar OC, Hernández-Acosta NC, González-Gómez M, Meyer G | title = Neurons in the white matter of the adult human neocortex | journal = Frontiers in Neuroanatomy | volume = 3 | pages = 7 | year = 2009 | pmid = 19543540 | pmc = 2697018 | doi = 10.3389/neuro.05.007.2009 | doi-access = free }}</ref> <ref name="bodyexpr">{{cite journal | vauthors = Smalheiser NR, Costa E, Guidotti A, Impagnatiello F, Auta J, Lacor P, Kriho V, Pappas GD | title = Expression of reelin in adult mammalian blood, liver, pituitary pars intermedia, and adrenal chromaffin cells | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 97 | issue = 3 | pages = 1281–6 | date = February 2000 | pmid = 10655522 | pmc = 15597 | doi = 10.1073/pnas.97.3.1281 | bibcode = 2000PNAS...97.1281S | doi-access = free }}</ref> <ref name="liver2">{{cite journal | vauthors = Samama B, Boehm N | title = Reelin immunoreactivity in lymphatics and liver during development and adult life | journal = The Anatomical Record Part A: Discoveries in Molecular, Cellular, and Evolutionary Biology | volume = 285 | issue = 1 | pages = 595–9 | date = July 2005 | pmid = 15912522 | doi = 10.1002/ar.a.20202 | doi-access = free }}</ref> <ref name="Kobold_2002_liver1">{{cite journal | vauthors = Kobold D, Grundmann A, Piscaglia F, Eisenbach C, Neubauer K, Steffgen J, Ramadori G, Knittel T | title = Expression of reelin in hepatic stellate cells and during hepatic tissue repair: a novel marker for the differentiation of HSC from other liver myofibroblasts | journal = Journal of Hepatology | volume = 36 | issue = 5 | pages = 607–13 | date = May 2002 | pmid = 11983443 | doi = 10.1016/S0168-8278(02)00050-8 }}</ref> <ref name="pmid17120005">{{cite journal | vauthors = Pulido JS, Sugaya I, Comstock J, Sugaya K | title = Reelin expression is upregulated following ocular tissue injury | journal = Graefe's Archive for Clinical and Experimental Ophthalmology | volume = 245 | issue = 6 | pages = 889–93 | date = June 2007 | pmid = 17120005 | doi = 10.1007/s00417-006-0458-4 | s2cid = 12397364 }}</ref> <ref name="pmid10980418">{{cite journal | vauthors = Buchaille R, Couble ML, Magloire H, Bleicher F | title = A substractive PCR-based cDNA library from human odontoblast cells: identification of novel genes expressed in tooth forming cells | journal = Matrix Biology | volume = 19 | issue = 5 | pages = 421–30 | date = September 2000 | pmid = 10980418 | doi = 10.1016/S0945-053X(00)00091-3 }}</ref> <ref name="pmid16831873">{{cite journal | vauthors = Allard B, Magloire H, Couble ML, Maurin JC, Bleicher F | title = Voltage-gated sodium channels confer excitability to human odontoblasts: possible role in tooth pain transmission | journal = The Journal of Biological Chemistry | volume = 281 | issue = 39 | pages = 29002–10 | date = September 2006 | pmid = 16831873 | doi = 10.1074/jbc.M601020200 | doi-access = free }}</ref> <ref name="pmid15464360">{{cite journal | vauthors = Maurin JC, Couble ML, Didier-Bazes M, Brisson C, Magloire H, Bleicher F | title = Expression and localization of reelin in human odontoblasts | journal = Matrix Biology | volume = 23 | issue = 5 | pages = 277–85 | date = August 2004 | pmid = 15464360 | doi = 10.1016/j.matbio.2004.06.005 }}</ref> <ref name="pmid17548821">{{PDB|2E26}}; {{cite journal | vauthors = Yasui N, Nogi T, Kitao T, Nakano Y, Hattori M, Takagi J | title = Structure of a receptor-binding fragment of reelin and mutational analysis reveal a recognition mechanism similar to endocytic receptors | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 104 | issue = 24 | pages = 9988–93 | date = June 2007 | pmid = 17548821 | pmc = 1891246 | doi = 10.1073/pnas.0700438104 | bibcode = 2007PNAS..104.9988Y | doi-access = free }}</ref> <ref name="pmid9417911">{{cite journal | vauthors = Royaux I, Lambert de Rouvroit C, D'Arcangelo G, Demirov D, Goffinet AM | title = Genomic organization of the mouse reelin gene | journal = Genomics | volume = 46 | issue = 2 | pages = 240–50 | date = December 1997 | pmid = 9417911 | doi = 10.1006/geno.1997.4983 }}</ref> <ref name="reelinstructure2006japan">{{PDB|2ddu}}; {{cite journal | vauthors = Nogi T, Yasui N, Hattori M, Iwasaki K, Takagi J | title = Structure of a signaling-competent reelin fragment revealed by X-ray crystallography and electron tomography | journal = The EMBO Journal | volume = 25 | issue = 15 | pages = 3675–83 | date = August 2006 | pmid = 16858396 | pmc = 1538547 | doi = 10.1038/sj.emboj.7601240 }}</ref> <ref name="Nakano_2007_CTR_1">{{cite journal | vauthors = Nakano Y, Kohno T, Hibi T, Kohno S, Baba A, Mikoshiba K, Nakajima K, Hattori M | title = The extremely conserved C-terminal region of Reelin is not necessary for secretion but is required for efficient activation of downstream signaling | journal = The Journal of Biological Chemistry | volume = 282 | issue = 28 | pages = 20544–52 | date = July 2007 | pmid = 17504759 | doi = 10.1074/jbc.M702300200 | doi-access = free }}</ref> <ref name="cleave">{{cite journal | vauthors = Lambert de Rouvroit C, de Bergeyck V, Cortvrindt C, Bar I, Eeckhout Y, Goffinet AM | title = Reelin, the extracellular matrix protein deficient in reeler mutant mice, is processed by a metalloproteinase | journal = Experimental Neurology | volume = 156 | issue = 1 | pages = 214–7 | date = March 1999 | pmid = 10192793 | doi = 10.1006/exnr.1998.7007 | s2cid = 35222830 }}</ref> <ref name="centralfragment">{{cite journal | vauthors = Jossin Y, Ignatova N, Hiesberger T, Herz J, Lambert de Rouvroit C, Goffinet AM | title = The central fragment of Reelin, generated by proteolytic processing in vivo, is critical to its function during cortical plate development | journal = The Journal of Neuroscience | volume = 24 | issue = 2 | pages = 514–21 | date = January 2004 | pmid = 14724251 | pmc = 6730001 | doi = 10.1523/JNEUROSCI.3408-03.2004 }}</ref> <ref name="pmid17442808">{{cite journal | vauthors = Jossin Y, Gui L, Goffinet AM | title = Processing of Reelin by embryonic neurons is important for function in tissue but not in dissociated cultured neurons | journal = The Journal of Neuroscience | volume = 27 | issue = 16 | pages = 4243–52 | date = April 2007 | pmid = 17442808 | pmc = 6672330 | doi = 10.1523/JNEUROSCI.0023-07.2007 }}</ref> <ref name="pmid14614786">{{cite journal | vauthors = Lennington JB, Yang Z, Conover JC | title = Neural stem cells and the regulation of adult neurogenesis | journal = Reproductive Biology and Endocrinology | volume = 1 | pages = 99 | date = November 2003 | pmid = 14614786 | pmc = 293430 | doi = 10.1186/1477-7827-1-99 | doi-access = free }}</ref> <ref name="pmid12925587">{{cite journal | vauthors = Hartfuss E, Förster E, Bock HH, Hack MA, Leprince P, Luque JM, Herz J, Frotscher M, Götz M | title = Reelin signaling directly affects radial glia morphology and biochemical maturation | journal = Development | volume = 130 | issue = 19 | pages = 4597–609 | date = October 2003 | pmid = 12925587 | doi = 10.1242/dev.00654 | doi-access = free | hdl = 10261/333510 | hdl-access = free }}</ref> <ref name="pmid18197264">{{cite journal | vauthors = Nomura T, Takahashi M, Hara Y, Osumi N | title = Patterns of neurogenesis and amplitude of Reelin expression are essential for making a mammalian-type cortex | journal = PLOS ONE | volume = 3 | issue = 1 | pages = e1454 | date = January 2008 | pmid = 18197264 | pmc = 2175532 | doi = 10.1371/journal.pone.0001454 | bibcode = 2008PLoSO...3.1454N | veditors = Reh T | doi-access = free }}</ref> <ref name="DerRio1997">{{cite journal | vauthors = Del Río JA, Heimrich B, Borrell V, Förster E, Drakew A, Alcántara S, Nakajima K, Miyata T, Ogawa M, Mikoshiba K, Derer P, Frotscher M, Soriano E | title = A role for Cajal-Retzius cells and reelin in the development of hippocampal connections | journal = Nature | volume = 385 | issue = 6611 | pages = 70–4 | date = January 1997 | pmid = 8985248 | doi = 10.1038/385070a0 | bibcode = 1997Natur.385...70D | s2cid = 4352996 }}</ref> <ref name="Borrell1999">{{cite journal | vauthors = Borrell V, Del Río JA, Alcántara S, Derer M, Martínez A, D'Arcangelo G, Nakajima K, Mikoshiba K, Derer P, Curran T, Soriano E | title = Reelin regulates the development and synaptogenesis of the layer-specific entorhino-hippocampal connections | journal = The Journal of Neuroscience | volume = 19 | issue = 4 | pages = 1345–58 | date = February 1999 | pmid = 9952412 | pmc = 6786030 | doi = 10.1523/JNEUROSCI.19-04-01345.1999}}</ref> <ref name="pmid16410414">{{cite journal | vauthors = Yoshida M, Assimacopoulos S, Jones KR, Grove EA | title = Massive loss of Cajal-Retzius cells does not disrupt neocortical layer order | journal = Development | volume = 133 | issue = 3 | pages = 537–45 | date = February 2006 | pmid = 16410414 | doi = 10.1242/dev.02209 | s2cid = 1702450 | doi-access = }}</ref> <ref name="pmid19412957">{{cite journal | vauthors = Yip YP, Mehta N, Magdaleno S, Curran T, Yip JW | title = Ectopic expression of reelin alters migration of sympathetic preganglionic neurons in the spinal cord | journal = The Journal of Comparative Neurology | volume = 515 | issue = 2 | pages = 260–8 | date = July 2009 | pmid = 19412957 | doi = 10.1002/cne.22044 | s2cid = 21832778 }}</ref> <ref name="roleofreelin1">{{cite journal | vauthors = Hack I, Bancila M, Loulier K, Carroll P, Cremer H | title = Reelin is a detachment signal in tangential chain-migration during postnatal neurogenesis | journal = Nature Neuroscience | volume = 5 | issue = 10 | pages = 939–45 | date = October 2002 | pmid = 12244323 | doi = 10.1038/nn923 | s2cid = 7096018 }}</ref> <ref name="pmid17494763">{{cite journal | vauthors = Andrade N, Komnenovic V, Blake SM, Jossin Y, Howell B, Goffinet A, Schneider WJ, Nimpf J | title = ApoER2/VLDL receptor and Dab1 in the rostral migratory stream function in postnatal neuronal migration independently of Reelin | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 104 | issue = 20 | pages = 8508–13 | date = May 2007 | pmid = 17494763 | pmc = 1895980 | doi = 10.1073/pnas.0611391104 | bibcode = 2007PNAS..104.8508A | doi-access = free }}</ref> <ref name="pmid18946489">{{cite journal | vauthors = Blake SM, Strasser V, Andrade N, Duit S, Hofbauer R, Schneider WJ, Nimpf J | title = Thrombospondin-1 binds to ApoER2 and VLDL receptor and functions in postnatal neuronal migration | journal = The EMBO Journal | volume = 27 | issue = 22 | pages = 3069–80 | date = November 2008 | pmid = 18946489 | pmc = 2585172 | doi = 10.1038/emboj.2008.223 }}</ref> <ref name="dentate_gyrus">{{cite journal | vauthors = Frotscher M, Haas CA, Förster E | title = Reelin controls granule cell migration in the dentate gyrus by acting on the radial glial scaffold | journal = Cerebral Cortex | volume = 13 | issue = 6 | pages = 634–40 | date = June 2003 | pmid = 12764039 | doi = 10.1093/cercor/13.6.634 | doi-access = free }}</ref> <ref name="OlivierManzoni">[http://www.inb.u-bordeaux2.fr/siteneuro2/pages/UniteINB/Manzoni/Manzoniavenir.htm INSERM – Olivier Manzoni – Physiopathology of Synaptic Transmission and Plasticity] {{webarchive|url=https://web.archive.org/web/20061125230210/http://www.inb.u-bordeaux2.fr/siteneuro2/pages/UniteINB/Manzoni/Manzoniavenir.htm |date=25 November 2006 }} – Bordo neuroscience institute.</ref> <ref name="pmid15987942">{{cite journal | vauthors = Sinagra M, Verrier D, Frankova D, Korwek KM, Blahos J, Weeber EJ, Manzoni OJ, Chavis P | title = Reelin, very-low-density lipoprotein receptor, and apolipoprotein E receptor 2 control somatic NMDA receptor composition during hippocampal maturation in vitro | journal = The Journal of Neuroscience | volume = 25 | issue = 26 | pages = 6127–36 | date = June 2005 | pmid = 15987942 | pmc = 6725049 | doi = 10.1523/JNEUROSCI.1757-05.2005 }}</ref> <ref name="pmid17881522">{{cite journal | vauthors = Groc L, Choquet D, Stephenson FA, Verrier D, Manzoni OJ, Chavis P | title = NMDA receptor surface trafficking and synaptic subunit composition are developmentally regulated by the extracellular matrix protein Reelin | journal = The Journal of Neuroscience | volume = 27 | issue = 38 | pages = 10165–75 | date = September 2007 | pmid = 17881522 | doi = 10.1523/JNEUROSCI.1772-07.2007 | pmc = 6672660 }}</ref> <ref name="pmid15470155">{{cite journal | vauthors = Liu XB, Murray KD, Jones EG | title = Switching of NMDA receptor 2A and 2B subunits at thalamic and cortical synapses during early postnatal development | journal = The Journal of Neuroscience | volume = 24 | issue = 40 | pages = 8885–95 | date = October 2004 | pmid = 15470155 | pmc = 6729956 | doi = 10.1523/JNEUROSCI.2476-04.2004 }}</ref> <ref name="pmid19430527">{{cite journal | vauthors = Campo CG, Sinagra M, Verrier D, Manzoni OJ, Chavis P | title = Reelin secreted by GABAergic neurons regulates glutamate receptor homeostasis | journal = PLOS ONE | volume = 4 | issue = 5 | pages = e5505 | year = 2009 | pmid = 19430527 | pmc = 2675077 | doi = 10.1371/journal.pone.0005505 | bibcode = 2009PLoSO...4.5505C | veditors = Okazawa H | doi-access = free }}</ref> <ref name="pmid11137154">{{cite journal | vauthors = Bar I, Lambert de Rouvroit C, Goffinet AM | title = The evolution of cortical development. An hypothesis based on the role of the Reelin signaling pathway | journal = Trends in Neurosciences | volume = 23 | issue = 12 | pages = 633–8 | date = December 2000 | pmid = 11137154 | doi = 10.1016/S0166-2236(00)01675-1 | s2cid = 13568642 }}</ref> <ref name="pmid16519657">{{cite journal | vauthors = Molnár Z, Métin C, Stoykova A, Tarabykin V, Price DJ, Francis F, Meyer G, Dehay C, Kennedy H | title = Comparative aspects of cerebral cortical development | journal = The European Journal of Neuroscience | volume = 23 | issue = 4 | pages = 921–34 | date = February 2006 | pmid = 16519657 | pmc = 1931431 | doi = 10.1111/j.1460-9568.2006.04611.x }}</ref> <ref name="pmid12124768">{{cite journal | vauthors = Costagli A, Kapsimali M, Wilson SW, Mione M | title = Conserved and divergent patterns of Reelin expression in the zebrafish central nervous system | journal = The Journal of Comparative Neurology | volume = 450 | issue = 1 | pages = 73–93 | date = August 2002 | pmid = 12124768 | doi = 10.1002/cne.10292 | s2cid = 23110916 }}</ref> <ref name="pmid11173219">{{cite journal | vauthors = Pérez-García CG, González-Delgado FJ, Suárez-Solá ML, Castro-Fuentes R, Martín-Trujillo JM, Ferres-Torres R, Meyer G | title = Reelin-immunoreactive neurons in the adult vertebrate pallium | journal = Journal of Chemical Neuroanatomy | volume = 21 | issue = 1 | pages = 41–51 | date = January 2001 | pmid = 11173219 | doi = 10.1016/S0891-0618(00)00104-6 | s2cid = 23395046 }}</ref> <ref name="pmid17132178">{{cite journal | vauthors = Goffinet AM | title = What makes us human? A biased view from the perspective of comparative embryology and mouse genetics | journal = Journal of Biomedical Discovery and Collaboration | volume = 1 | pages = 16 | date = November 2006 | pmid = 17132178 | pmc = 1769396 | doi = 10.1186/1747-5333-1-16 | doi-access = free }}</ref> <ref name="pmid16915236">{{cite journal | vauthors = Pollard KS, Salama SR, Lambert N, Lambot MA, Coppens S, Pedersen JS, Katzman S, King B, Onodera C, Siepel A, Kern AD, Dehay C, Igel H, Ares M, Vanderhaeghen P, Haussler D | title = An RNA gene expressed during cortical development evolved rapidly in humans | journal = Nature | volume = 443 | issue = 7108 | pages = 167–72 | date = September 2006 | pmid = 16915236 | doi = 10.1038/nature05113 | bibcode = 2006Natur.443..167P | s2cid = 18107797 | url = https://dipot.ulb.ac.be/dspace/bitstream/2013/51805/3/pollard2006.pdf }}</ref> <ref name="pmid17542651">{{cite journal | vauthors = Williamson SH, Hubisz MJ, Clark AG, Payseur BA, Bustamante CD, Nielsen R | title = Localizing recent adaptive evolution in the human genome | journal = PLOS Genetics | volume = 3 | issue = 6 | pages = e90 | date = June 2007 | pmid = 17542651 | pmc = 1885279 | doi = 10.1371/journal.pgen.0030090 | doi-access = free }}</ref> <ref name="NYT1">{{cite news | url = https://www.nytimes.com/2007/06/26/science/26human.html?pagewanted=1 | title = Humans Have Spread Globally, and Evolved Locally | vauthors = Wade N | date = 26 June 2007 | newspaper = The New York Times | access-date = 23 August 2008 }}</ref> <ref name="integrin">{{cite journal | vauthors = Schmid RS, Jo R, Shelton S, Kreidberg JA, Anton ES | title = Reelin, integrin and DAB1 interactions during embryonic cerebral cortical development | journal = Cerebral Cortex | volume = 15 | issue = 10 | pages = 1632–6 | date = October 2005 | pmid = 15703255 | doi = 10.1093/cercor/bhi041 | doi-access = free }}</ref> <ref name="cadherin">{{cite journal | vauthors = Senzaki K, Ogawa M, Yagi T | title = Proteins of the CNR family are multiple receptors for Reelin | journal = Cell | volume = 99 | issue = 6 | pages = 635–47 | date = December 1999 | pmid = 10612399 | doi = 10.1016/S0092-8674(00)81552-4 | s2cid = 14277878 | doi-access = free }}</ref> <ref name="pmid18077697">{{cite journal | vauthors = Belvindrah R, Graus-Porta D, Goebbels S, Nave KA, Müller U | title = Beta1 integrins in radial glia but not in migrating neurons are essential for the formation of cell layers in the cerebral cortex | journal = The Journal of Neuroscience | volume = 27 | issue = 50 | pages = 13854–65 | date = December 2007 | pmid = 18077697 | pmc = 6673609 | doi = 10.1523/JNEUROSCI.4494-07.2007 }}</ref> <ref name="pmid9009273">{{cite journal | vauthors = Howell BW, Gertler FB, Cooper JA | title = Mouse disabled (mDab1): a Src binding protein implicated in neuronal development | journal = The EMBO Journal | volume = 16 | issue = 1 | pages = 121–32 | date = January 1997 | pmid = 9009273 | pmc = 1169619 | doi = 10.1093/emboj/16.1.121 }}</ref> <ref name="pmid12526739">{{cite journal | vauthors = Arnaud L, Ballif BA, Förster E, Cooper JA | title = Fyn tyrosine kinase is a critical regulator of disabled-1 during brain development | journal = Current Biology | volume = 13 | issue = 1 | pages = 9–17 | date = January 2003 | pmid = 12526739 | doi = 10.1016/S0960-9822(02)01397-0 | s2cid = 1739505 | doi-access = free | bibcode = 2003CBio...13....9A }}</ref> <ref name="pmid17974915">{{cite journal | vauthors = Feng L, Allen NS, Simo S, Cooper JA | title = Cullin 5 regulates Dab1 protein levels and neuron positioning during cortical development | journal = Genes & Development | volume = 21 | issue = 21 | pages = 2717–30 | date = November 2007 | pmid = 17974915 | pmc = 2045127 | doi = 10.1101/gad.1604207 }}</ref> <ref name="pmid18006681">{{cite journal | vauthors = Kerjan G, Gleeson JG | title = A missed exit: Reelin sets in motion Dab1 polyubiquitination to put the break on neuronal migration | journal = Genes & Development | volume = 21 | issue = 22 | pages = 2850–4 | date = November 2007 | pmid = 18006681 | doi = 10.1101/gad.1622907 | doi-access = free }}</ref> <ref name="Zhang_2007_Pafah1b">{{cite journal | vauthors = Zhang G, Assadi AH, McNeil RS, Beffert U, Wynshaw-Boris A, Herz J, Clark GD, D'Arcangelo G | title = The Pafah1b complex interacts with the reelin receptor VLDLR | journal = PLOS ONE | volume = 2 | issue = 2 | pages = e252 | date = February 2007 | pmid = 17330141 | pmc = 1800349 | doi = 10.1371/journal.pone.0000252 | bibcode = 2007PLoSO...2..252Z | veditors = Mueller U | doi-access = free }}</ref> <ref name="pmid17913789">{{cite journal | vauthors = Hack I, Hellwig S, Junghans D, Brunne B, Bock HH, Zhao S, Frotscher M | title = Divergent roles of ApoER2 and Vldlr in the migration of cortical neurons | journal = Development | volume = 134 | issue = 21 | pages = 3883–91 | date = November 2007 | pmid = 17913789 | doi = 10.1242/dev.005447 | doi-access = free }}</ref> <ref name="hugecomplex">{{cite journal | vauthors = Utsunomiya-Tate N, Kubo K, Tate S, Kainosho M, Katayama E, Nakajima K, Mikoshiba K | title = Reelin molecules assemble together to form a large protein complex, which is inhibited by the function-blocking CR-50 antibody | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 97 | issue = 17 | pages = 9729–34 | date = August 2000 | pmid = 10920200 | pmc = 16933 | doi = 10.1073/pnas.160272497 | bibcode = 2000PNAS...97.9729U | doi-access = free }}</ref> <ref name="complex">{{cite journal | vauthors = Kubo K, Mikoshiba K, Nakajima K | title = Secreted Reelin molecules form homodimers | journal = Neuroscience Research | volume = 43 | issue = 4 | pages = 381–8 | date = August 2002 | pmid = 12135781 | doi = 10.1016/S0168-0102(02)00068-8 | s2cid = 10656560 }}</ref> <ref name="pmid14729980">{{cite journal | vauthors = Strasser V, Fasching D, Hauser C, Mayer H, Bock HH, Hiesberger T, Herz J, Weeber EJ, Sweatt JD, Pramatarova A, Howell B, Schneider WJ, Nimpf J | title = Receptor clustering is involved in Reelin signaling | journal = Molecular and Cellular Biology | volume = 24 | issue = 3 | pages = 1378–86 | date = February 2004 | pmid = 14729980 | pmc = 321426 | doi = 10.1128/MCB.24.3.1378-1386.2004 }}</ref> <ref name="pmid11689558">{{cite journal | vauthors = Quattrocchi CC, Wannenes F, Persico AM, Ciafré SA, D'Arcangelo G, Farace MG, Keller F | title = Reelin is a serine protease of the extracellular matrix | journal = The Journal of Biological Chemistry | volume = 277 | issue = 1 | pages = 303–9 | date = January 2002 | pmid = 11689558 | doi = 10.1074/jbc.M106996200 | doi-access = free | hdl = 11380/1250927 | hdl-access = free }}</ref> <ref name="Reelin_ApoER2_Exon19_2005_Beffert">{{cite journal | vauthors = Beffert U, Weeber EJ, Durudas A, Qiu S, Masiulis I, Sweatt JD, Li WP, Adelmann G, Frotscher M, Hammer RE, Herz J | title = Modulation of synaptic plasticity and memory by Reelin involves differential splicing of the lipoprotein receptor Apoer2 | journal = Neuron | volume = 47 | issue = 4 | pages = 567–79 | date = August 2005 | pmid = 16102539 | doi = 10.1016/j.neuron.2005.07.007 | s2cid = 5854936 | doi-access = free }}</ref> <ref name="pmid17359920">{{cite journal | vauthors = Miller CA, Sweatt JD | title = Covalent modification of DNA regulates memory formation | journal = Neuron | volume = 53 | issue = 6 | pages = 857–69 | date = March 2007 | pmid = 17359920 | doi = 10.1016/j.neuron.2007.02.022 | s2cid = 62791264 | doi-access = free }}</ref> <ref name="pmid18477607">{{cite journal | vauthors = Matsuki T, Pramatarova A, Howell BW | title = Reduction of Crk and CrkL expression blocks reelin-induced dendritogenesis | journal = Journal of Cell Science | volume = 121 | issue = 11 | pages = 1869–75 | date = June 2008 | pmid = 18477607 | pmc = 2430739 | doi = 10.1242/jcs.027334 }}</ref> <ref name="pmid15062102">{{cite journal | vauthors = Ballif BA, Arnaud L, Arthur WT, Guris D, Imamoto A, Cooper JA | title = Activation of a Dab1/CrkL/C3G/Rap1 pathway in Reelin-stimulated neurons | journal = Current Biology | volume = 14 | issue = 7 | pages = 606–10 | date = April 2004 | pmid = 15062102 | doi = 10.1016/j.cub.2004.03.038 | s2cid = 52887334 | doi-access = free | bibcode = 2004CBio...14..606B }}</ref> <ref name="pmid19074029">{{cite journal | vauthors = Park TJ, Curran T | title = Crk and Crk-like play essential overlapping roles downstream of disabled-1 in the Reelin pathway | journal = The Journal of Neuroscience | volume = 28 | issue = 50 | pages = 13551–62 | date = December 2008 | pmid = 19074029 | pmc = 2628718 | doi = 10.1523/JNEUROSCI.4323-08.2008 }}</ref> <ref name="pmid18593473">{{cite journal | vauthors = Keilani S, Sugaya K | title = Reelin induces a radial glial phenotype in human neural progenitor cells by activation of Notch-1 | journal = BMC Developmental Biology | volume = 8 | issue = 1 | pages = 69 | date = July 2008 | pmid = 18593473 | pmc = 2447831 | doi = 10.1186/1471-213X-8-69 | doi-access = free }}</ref> <ref name="pmid12959647">{{cite journal | vauthors = Lugli G, Krueger JM, Davis JM, Persico AM, Keller F, Smalheiser NR | title = Methodological factors influencing measurement and processing of plasma reelin in humans | journal = BMC Biochemistry | volume = 4 | pages = 9 | date = September 2003 | pmid = 12959647 | pmc = 200967 | doi = 10.1186/1471-2091-4-9 | doi-access = free }}</ref> <ref name="pmid19303411">{{cite journal | vauthors = Hibi T, Hattori M | title = The N-terminal fragment of Reelin is generated after endocytosis and released through the pathway regulated by Rab11 | journal = FEBS Letters | volume = 583 | issue = 8 | pages = 1299–303 | date = April 2009 | pmid = 19303411 | doi = 10.1016/j.febslet.2009.03.024 | s2cid = 43542615 | doi-access = free | bibcode = 2009FEBSL.583.1299H }}</ref> <ref name="pmid19366679">{{cite journal | vauthors = Chameau P, Inta D, Vitalis T, Monyer H, Wadman WJ, van Hooft JA | title = The N-terminal region of reelin regulates postnatal dendritic maturation of cortical pyramidal neurons | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 106 | issue = 17 | pages = 7227–32 | date = April 2009 | pmid = 19366679 | pmc = 2678467 | doi = 10.1073/pnas.0810764106 | bibcode = 2009PNAS..106.7227C | doi-access = free }}</ref> <ref name="pmid19129405">{{cite journal | vauthors = Chai X, Förster E, Zhao S, Bock HH, Frotscher M | title = Reelin stabilizes the actin cytoskeleton of neuronal processes by inducing n-cofilin phosphorylation at serine3 | journal = The Journal of Neuroscience | volume = 29 | issue = 1 | pages = 288–99 | date = January 2009 | pmid = 19129405 | pmc = 6664910 | doi = 10.1523/JNEUROSCI.2934-08.2009 }}</ref> <ref name="pmid19396394">{{cite journal | vauthors = Frotscher M, Chai X, Bock HH, Haas CA, Förster E, Zhao S | title = Role of Reelin in the development and maintenance of cortical lamination | journal = Journal of Neural Transmission | volume = 116 | issue = 11 | pages = 1451–5 | date = November 2009 | pmid = 19396394 | doi = 10.1007/s00702-009-0228-7 | s2cid = 1310387 }}</ref> <ref name="pmid14645539">{{cite journal | vauthors = Arnaud L, Ballif BA, Cooper JA | title = Regulation of protein tyrosine kinase signaling by substrate degradation during brain development | journal = Molecular and Cellular Biology | volume = 23 | issue = 24 | pages = 9293–302 | date = December 2003 | pmid = 14645539 | pmc = 309695 | doi = 10.1128/MCB.23.24.9293-9302.2003 }}</ref> <ref name="pmid16529723">{{cite journal | vauthors = Ohshima T, Suzuki H, Morimura T, Ogawa M, Mikoshiba K | title = Modulation of Reelin signaling by Cyclin-dependent kinase 5 | journal = Brain Research | volume = 1140 | pages = 84–95 | date = April 2007 | pmid = 16529723 | doi = 10.1016/j.brainres.2006.01.121 | s2cid = 23991327 }}</ref> <ref name="pmid12077184">{{cite journal | vauthors = Keshvara L, Magdaleno S, Benhayon D, Curran T | title = Cyclin-dependent kinase 5 phosphorylates disabled 1 independently of Reelin signaling | journal = The Journal of Neuroscience | volume = 22 | issue = 12 | pages = 4869–77 | date = June 2002 | pmid = 12077184 | pmc = 6757745 | doi = 10.1523/JNEUROSCI.22-12-04869.2002}}</ref> <ref name="pmid8253190">{{cite journal | vauthors = Kobayashi S, Ishiguro K, Omori A, Takamatsu M, Arioka M, Imahori K, Uchida T | title = A cdc2-related kinase PSSALRE/cdk5 is homologous with the 30 kDa subunit of tau protein kinase II, a proline-directed protein kinase associated with microtubule | journal = FEBS Letters | volume = 335 | issue = 2 | pages = 171–5 | date = December 1993 | pmid = 8253190 | doi = 10.1016/0014-5793(93)80723-8 | s2cid = 26474408 | doi-access = | bibcode = 1993FEBSL.335..171K }}</ref> <ref name="pmid12376533">{{cite journal | vauthors = Beffert U, Morfini G, Bock HH, Reyna H, Brady ST, Herz J | title = Reelin-mediated signaling locally regulates protein kinase B/Akt and glycogen synthase kinase 3beta | journal = The Journal of Biological Chemistry | volume = 277 | issue = 51 | pages = 49958–64 | date = December 2002 | pmid = 12376533 | doi = 10.1074/jbc.M209205200 | doi-access = free }}</ref> <ref name="pmid11163259">{{cite journal | vauthors = Sasaki S, Shionoya A, Ishida M, Gambello MJ, Yingling J, Wynshaw-Boris A, Hirotsune S | title = A LIS1/NUDEL/cytoplasmic dynein heavy chain complex in the developing and adult nervous system | journal = Neuron | volume = 28 | issue = 3 | pages = 681–96 | date = December 2000 | pmid = 11163259 | doi = 10.1016/S0896-6273(00)00146-X | s2cid = 17738599 | doi-access = free }}</ref> <ref name="pmid14985430">{{cite journal | vauthors = Beffert U, Weeber EJ, Morfini G, Ko J, Brady ST, Tsai LH, Sweatt JD, Herz J | title = Reelin and cyclin-dependent kinase 5-dependent signals cooperate in regulating neuronal migration and synaptic transmission | journal = The Journal of Neuroscience | volume = 24 | issue = 8 | pages = 1897–906 | date = February 2004 | pmid = 14985430 | pmc = 6730409 | doi = 10.1523/JNEUROSCI.4084-03.2004 }}</ref> <ref name="pmid11226314">{{cite journal | vauthors = Ohshima T, Ogawa M, Hirasawa M, Longenecker G, Ishiguro K, Pant HC, Brady RO, Kulkarni AB, Mikoshiba K | title = Synergistic contributions of cyclin-dependant kinase 5/p35 and Reelin/Dab1 to the positioning of cortical neurons in the developing mouse brain | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 98 | issue = 5 | pages = 2764–9 | date = February 2001 | pmid = 11226314 | pmc = 30213 | doi = 10.1073/pnas.051628498 | bibcode = 2001PNAS...98.2764O | doi-access = free }}</ref> <ref name="liss2000">{{cite journal | vauthors = Hong SE, Shugart YY, Huang DT, Shahwan SA, Grant PE, Hourihane JO, Martin ND, Walsh CA | title = Autosomal recessive lissencephaly with cerebellar hypoplasia is associated with human RELN mutations | journal = Nature Genetics | volume = 26 | issue = 1 | pages = 93–6 | date = September 2000 | pmid = 10973257 | doi = 10.1038/79246 | s2cid = 67748801 }}</ref> <ref name="liss2001">{{cite journal | vauthors = Crino P | title = New RELN Mutation Associated with Lissencephaly and Epilepsy | journal = Epilepsy Currents | volume = 1 | issue = 2 | pages = 72–73 | date = November 2001 | pmid = 15309195 | pmc = 320825 | doi = 10.1046/j.1535-7597.2001.00017.x }}</ref> <ref name="pmid17431900">{{cite journal | vauthors = Zaki M, Shehab M, El-Aleem AA, Abdel-Salam G, Koeller HB, Ilkin Y, Ross ME, Dobyns WB, Gleeson JG | title = Identification of a novel recessive RELN mutation using a homozygous balanced reciprocal translocation | journal = American Journal of Medical Genetics. Part A | volume = 143A | issue = 9 | pages = 939–44 | date = May 2007 | pmid = 17431900 | doi = 10.1002/ajmg.a.31667 | s2cid = 19126812 }}</ref> <ref name="szproof1">{{cite journal | vauthors = Impagnatiello F, Guidotti AR, Pesold C, Dwivedi Y, Caruncho H, Pisu MG, Uzunov DP, Smalheiser NR, Davis JM, Pandey GN, Pappas GD, Tueting P, Sharma RP, Costa E | title = A decrease of reelin expression as a putative vulnerability factor in schizophrenia | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 95 | issue = 26 | pages = 15718–23 | date = December 1998 | pmid = 9861036 | pmc = 28110 | doi = 10.1073/pnas.95.26.15718 | bibcode = 1998PNAS...9515718I | doi-access = free }}</ref> <ref name="szproof2">{{cite journal | vauthors = Guidotti A, Auta J, Davis JM, Di-Giorgi-Gerevini V, Dwivedi Y, Grayson DR, Impagnatiello F, Pandey G, Pesold C, Sharma R, Uzunov D, Costa E, DiGiorgi Gerevini V | title = Decrease in reelin and glutamic acid decarboxylase67 (GAD67) expression in schizophrenia and bipolar disorder: a postmortem brain study | journal = Archives of General Psychiatry | volume = 57 | issue = 11 | pages = 1061–9 | date = November 2000 | pmid = 11074872 | doi = 10.1001/archpsyc.57.11.1061 | doi-access = }}</ref> <ref name="szconfirm1">{{cite journal | vauthors = Fatemi SH, Earle JA, McMenomy T | title = Reduction in Reelin immunoreactivity in hippocampus of subjects with schizophrenia, bipolar disorder and major depression | journal = Molecular Psychiatry | volume = 5 | issue = 6 | pages = 654–63, 571 | date = November 2000 | pmid = 11126396 | doi = 10.1038/sj.mp.4000783 | doi-access = free }}</ref> <ref name="BDP_basal_ganglia_2007">{{cite journal | vauthors = Veldic M, Kadriu B, Maloku E, Agis-Balboa RC, Guidotti A, Davis JM, Costa E | title = Epigenetic mechanisms expressed in basal ganglia GABAergic neurons differentiate schizophrenia from bipolar disorder | journal = Schizophrenia Research | volume = 91 | issue = 1–3 | pages = 51–61 | date = March 2007 | pmid = 17270400 | pmc = 1876737 | doi = 10.1016/j.schres.2006.11.029 }}</ref> <ref name="szconfirm2">{{cite journal | vauthors = Eastwood SL, Harrison PJ | title = Interstitial white matter neurons express less reelin and are abnormally distributed in schizophrenia: towards an integration of molecular and morphologic aspects of the neurodevelopmental hypothesis | journal = Molecular Psychiatry | volume = 8 | issue = 9 | pages = 769, 821–31 | date = September 2003 | pmid = 12931209 | doi = 10.1038/sj.mp.4001371 | s2cid = 25020557 | doi-access = }}</ref> <ref name="szconfirm3">{{cite journal | vauthors = Abdolmaleky HM, Cheng KH, Russo A, Smith CL, Faraone SV, Wilcox M, Shafa R, Glatt SJ, Nguyen G, Ponte JF, Thiagalingam S, Tsuang MT | title = Hypermethylation of the reelin (RELN) promoter in the brain of schizophrenic patients: a preliminary report | journal = American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics | volume = 134B | issue = 1 | pages = 60–6 | date = April 2005 | pmid = 15717292 | doi = 10.1002/ajmg.b.30140 | s2cid = 23169492 }}</ref> <ref name="pmid15560956">{{cite journal | vauthors = Fatemi SH, Hossein Fatemi S, Stary JM, Earle JA, Araghi-Niknam M, Eagan E | title = GABAergic dysfunction in schizophrenia and mood disorders as reflected by decreased levels of glutamic acid decarboxylase 65 and 67 kDa and Reelin proteins in cerebellum | journal = Schizophrenia Research | volume = 72 | issue = 2–3 | pages = 109–22 | date = January 2005 | pmid = 15560956 | doi = 10.1016/j.schres.2004.02.017 | s2cid = 35193802 }}</ref> <ref name="fatemi_blood_reelin">{{cite journal | vauthors = Fatemi SH, Kroll JL, Stary JM | title = Altered levels of Reelin and its isoforms in schizophrenia and mood disorders | journal = NeuroReport | volume = 12 | issue = 15 | pages = 3209–15 | date = October 2001 | pmid = 11711858 | doi = 10.1097/00001756-200110290-00014 | s2cid = 43077109 }}</ref> <ref name="Knable_2001">{{cite journal | vauthors = Knable MB, Torrey EF, Webster MJ, Bartko JJ | title = Multivariate analysis of prefrontal cortical data from the Stanley Foundation Neuropathology Consortium | journal = Brain Research Bulletin | volume = 55 | issue = 5 | pages = 651–9 | date = July 2001 | pmid = 11576762 | doi = 10.1016/S0361-9230(01)00521-4 | s2cid = 23427111 }}</ref> <ref name="hypermeth">{{cite journal | vauthors = Grayson DR, Jia X, Chen Y, Sharma RP, Mitchell CP, Guidotti A, Costa E | title = Reelin promoter hypermethylation in schizophrenia | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 102 | issue = 26 | pages = 9341–6 | date = June 2005 | pmid = 15961543 | pmc = 1166626 | doi = 10.1073/pnas.0503736102 | bibcode = 2005PNAS..102.9341G | doi-access = free }}</ref> <ref name="dong">{{cite journal | vauthors = Dong E, Agis-Balboa RC, Simonini MV, Grayson DR, Costa E, Guidotti A | title = Reelin and glutamic acid decarboxylase67 promoter remodeling in an epigenetic methionine-induced mouse model of schizophrenia | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 102 | issue = 35 | pages = 12578–83 | date = August 2005 | pmid = 16113080 | pmc = 1194936 | doi = 10.1073/pnas.0505394102 | bibcode = 2005PNAS..10212578D | doi-access = free }}</ref> <ref name="methionine1">{{cite journal | vauthors = Pollin W, Cardon PV, Kety SS | title = Effects of amino acid feedings in schizophrenic patients treated with iproniazid | journal = Science | volume = 133 | issue = 3446 | pages = 104–5 | date = January 1961 | pmid = 13736870 | doi = 10.1126/science.133.3446.104 | bibcode = 1961Sci...133..104P | s2cid = 32080078 }}</ref> <ref name="methionine2">{{cite journal | vauthors = Brune GG, Himwich HE | title = Effects of methionine loading on the behavior of schizophrenic patients | journal = The Journal of Nervous and Mental Disease | volume = 134 | issue = 5 | pages = 447–50 | date = May 1962 | pmid = 13873983 | doi = 10.1097/00005053-196205000-00007 | s2cid = 46617457 }}</ref> <ref name="methionine3">{{cite journal | vauthors = Park LC, Baldessarini RJ, Kety SS | journal = Archives of General Psychiatry | volume = 12 | issue = 4 | pages = 346–51 | date = April 1965 | pmid = 14258360 | doi = 10.1001/archpsyc.1965.01720340018003 | title = Methionine Effects on Chronic Schizophrenics }}</ref> <ref name="methionine4">{{cite journal | vauthors = Antun FT, Burnett GB, Cooper AJ, Daly RJ, Smythies JR, Zealley AK | title = The effects of L-methionine (without MAOI) in schizophrenia | journal = Journal of Psychiatric Research | volume = 8 | issue = 2 | pages = 63–71 | date = June 1971 | pmid = 4932991 | doi = 10.1016/0022-3956(71)90009-4 }}</ref> <ref name="epigenetic2007">{{cite journal | vauthors = Ruzicka WB, Zhubi A, Veldic M, Grayson DR, Costa E, Guidotti A | title = Selective epigenetic alteration of layer I GABAergic neurons isolated from prefrontal cortex of schizophrenia patients using laser-assisted microdissection | journal = Molecular Psychiatry | volume = 12 | issue = 4 | pages = 385–97 | date = April 2007 | pmid = 17264840 | doi = 10.1038/sj.mp.4001954 | s2cid = 24045153 | doi-access = }}</ref> <ref name="DNMT_inhibition_GAD67_Reelin_2004">{{cite journal | vauthors = Veldic M, Caruncho HJ, Liu WS, Davis J, Satta R, Grayson DR, Guidotti A, Costa E | title = DNA-methyltransferase 1 mRNA is selectively overexpressed in telencephalic GABAergic interneurons of schizophrenia brains | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 101 | issue = 1 | pages = 348–53 | date = January 2004 | pmid = 14684836 | pmc = 314188 | doi = 10.1073/pnas.2637013100 | bibcode = 2004PNAS..101..348V | doi-access = free }}</ref> <ref name="pmid15684088">{{cite journal | vauthors = Veldic M, Guidotti A, Maloku E, Davis JM, Costa E | title = In psychosis, cortical interneurons overexpress DNA-methyltransferase 1 | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 102 | issue = 6 | pages = 2152–7 | date = February 2005 | pmid = 15684088 | pmc = 548582 | doi = 10.1073/pnas.0409665102 | bibcode = 2005PNAS..102.2152V | doi-access = free }}</ref> <ref name="valpro">{{cite journal | vauthors = Tremolizzo L, Doueiri MS, Dong E, Grayson DR, Davis J, Pinna G, Tueting P, Rodriguez-Menendez V, Costa E, Guidotti A | title = Valproate corrects the schizophrenia-like epigenetic behavioral modifications induced by methionine in mice | journal = Biological Psychiatry | volume = 57 | issue = 5 | pages = 500–9 | date = March 2005 | pmid = 15737665 | doi = 10.1016/j.biopsych.2004.11.046 | s2cid = 29868395 }}</ref> <ref name="valproicreelin">{{cite journal | vauthors = Chen Y, Sharma RP, Costa RH, Costa E, Grayson DR | title = On the epigenetic regulation of the human reelin promoter | journal = Nucleic Acids Research | volume = 30 | issue = 13 | pages = 2930–9 | date = July 2002 | pmid = 12087179 | pmc = 117056 | doi = 10.1093/nar/gkf401 }}</ref> <ref name="Mitchell">{{cite journal | vauthors = Mitchell CP, Chen Y, Kundakovic M, Costa E, Grayson DR | title = Histone deacetylase inhibitors decrease reelin promoter methylation in vitro | journal = Journal of Neurochemistry | volume = 93 | issue = 2 | pages = 483–92 | date = April 2005 | pmid = 15816871 | doi = 10.1111/j.1471-4159.2005.03040.x | s2cid = 12445076 }}</ref> <ref name="l-meth">{{cite journal | vauthors = Tremolizzo L, Carboni G, Ruzicka WB, Mitchell CP, Sugaya I, Tueting P, Sharma R, Grayson DR, Costa E, Guidotti A | title = An epigenetic mouse model for molecular and behavioral neuropathologies related to schizophrenia vulnerability | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 99 | issue = 26 | pages = 17095–100 | date = December 2002 | pmid = 12481028 | pmc = 139275 | doi = 10.1073/pnas.262658999 | bibcode = 2002PNAS...9917095T | doi-access = free }}</ref> <ref name="pmid17553960">{{cite journal | vauthors = Benes FM, Lim B, Matzilevich D, Walsh JP, Subburaju S, Minns M | title = Regulation of the GABA cell phenotype in hippocampus of schizophrenics and bipolars | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 104 | issue = 24 | pages = 10164–9 | date = June 2007 | pmid = 17553960 | pmc = 1888575 | doi = 10.1073/pnas.0703806104 | bibcode = 2007PNAS..10410164B | doi-access = free }}</ref> <ref name="Dong_2007">{{cite journal | vauthors = Dong E, Guidotti A, Grayson DR, Costa E | title = Histone hyperacetylation induces demethylation of reelin and 67-kDa glutamic acid decarboxylase promoters | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 104 | issue = 11 | pages = 4676–81 | date = March 2007 | pmid = 17360583 | pmc = 1815468 | doi = 10.1073/pnas.0700529104 | bibcode = 2007PNAS..104.4676D | doi-access = free }}</ref> <ref name="DNMT_inhibition_GAD67_Reelin_2006">{{cite journal | vauthors = Kundakovic M, Chen Y, Costa E, Grayson DR | title = DNA methyltransferase inhibitors coordinately induce expression of the human reelin and glutamic acid decarboxylase 67 genes | journal = Molecular Pharmacology | volume = 71 | issue = 3 | pages = 644–53 | date = March 2007 | pmid = 17065238 | doi = 10.1124/mol.106.030635 | s2cid = 18421124 }}</ref> <ref name="pmid19029285">{{cite journal | vauthors = Kundakovic M, Chen Y, Guidotti A, Grayson DR | title = The reelin and GAD67 promoters are activated by epigenetic drugs that facilitate the disruption of local repressor complexes | journal = Molecular Pharmacology | volume = 75 | issue = 2 | pages = 342–54 | date = February 2009 | pmid = 19029285 | pmc = 2684898 | doi = 10.1124/mol.108.051763 }}</ref> <ref name="SAM_and_DNMT1_psychosis_2007">{{cite journal | vauthors = Guidotti A, Ruzicka W, Grayson DR, Veldic M, Pinna G, Davis JM, Costa E | title = S-adenosyl methionine and DNA methyltransferase-1 mRNA overexpression in psychosis | journal = NeuroReport | volume = 18 | issue = 1 | pages = 57–60 | date = January 2007 | pmid = 17259861 | doi = 10.1097/WNR.0b013e32800fefd7 | s2cid = 25378736 }}</ref> <!--unused<ref name="influenza1">{{cite journal | vauthors = Fatemi SH, Emamian ES, Kist D, Sidwell RW, Nakajima K, Akhter P, Shier A, Sheikh S, Bailey K | title = Defective corticogenesis and reduction in Reelin immunoreactivity in cortex and hippocampus of prenatally infected neonatal mice | journal = Molecular Psychiatry | volume = 4 | issue = 2 | pages = 145–54 | date = March 1999 | pmid = 10208446 | doi = 10.1038/sj.mp.4000520 }}</ref>--> <!--unused<ref name="pmid18023140">{{cite journal | vauthors = Meyer U, Nyffeler M, Yee BK, Knuesel I, Feldon J | title = Adult brain and behavioral pathological markers of prenatal immune challenge during early/middle and late fetal development in mice | journal = Brain, Behavior, and Immunity | volume = 22 | issue = 4 | pages = 469–86 | date = May 2008 | pmid = 18023140 | doi = 10.1016/j.bbi.2007.09.012 }}</ref>--> <ref name="pmid17684500">{{cite journal | vauthors = Wedenoja J, Loukola A, Tuulio-Henriksson A, Paunio T, Ekelund J, Silander K, Varilo T, Heikkilä K, Suvisaari J, Partonen T, Lönnqvist J, Peltonen L | title = Replication of linkage on chromosome 7q22 and association of the regional Reelin gene with working memory in schizophrenia families | journal = Molecular Psychiatry | volume = 13 | issue = 7 | pages = 673–84 | date = July 2008 | pmid = 17684500 | doi = 10.1038/sj.mp.4002047 | s2cid = 20658493 | doi-access = }}</ref> <ref name="pmid18282107">{{cite journal | vauthors = Shifman S, Johannesson M, Bronstein M, Chen SX, Collier DA, Craddock NJ, Kendler KS, Li T, O'Donovan M, O'Neill FA, Owen MJ, Walsh D, Weinberger DR, Sun C, Flint J, Darvasi A | title = Genome-wide association identifies a common variant in the reelin gene that increases the risk of schizophrenia only in women | journal = PLOS Genetics | volume = 4 | issue = 2 | pages = e28 | date = February 2008 | pmid = 18282107 | pmc = 2242812 | doi = 10.1371/journal.pgen.0040028 | doi-access = free }} [https://archive.today/20130113061137/http://genetics.plosjournals.org/perlserv/?request=get-document&doi=10.1371/journal.pgen.0040028 free full text]</ref> <ref name="pmid19054571">{{cite journal | vauthors = Gregório SP, Sallet PC, Do KA, Lin E, Gattaz WF, Dias-Neto E | title = Polymorphisms in genes involved in neurodevelopment may be associated with altered brain morphology in schizophrenia: preliminary evidence | journal = Psychiatry Research | volume = 165 | issue = 1–2 | pages = 1–9 | date = January 2009 | pmid = 19054571 | doi = 10.1016/j.psychres.2007.08.011 | s2cid = 43548414 }}</ref> <ref name="pmid17936586">{{cite journal | vauthors = Suzuki K, Nakamura K, Iwata Y, Sekine Y, Kawai M, Sugihara G, Tsuchiya KJ, Suda S, Matsuzaki H, Takei N, Hashimoto K, Mori N | title = Decreased expression of reelin receptor VLDLR in peripheral lymphocytes of drug-naive schizophrenic patients | journal = Schizophrenia Research | volume = 98 | issue = 1–3 | pages = 148–56 | date = January 2008 | pmid = 17936586 | doi = 10.1016/j.schres.2007.09.029 | s2cid = 45594329 }}</ref> <ref name="pmid18463626">{{cite journal | vauthors = Sweet RA, Henteleff RA, Zhang W, Sampson AR, Lewis DA | title = Reduced dendritic spine density in auditory cortex of subjects with schizophrenia | journal = Neuropsychopharmacology | volume = 34 | issue = 2 | pages = 374–89 | date = January 2009 | pmid = 18463626 | pmc = 2775717 | doi = 10.1038/npp.2008.67 }}</ref> <ref name="pmid10632234">{{cite journal | vauthors = Glantz LA, Lewis DA | title = Decreased dendritic spine density on prefrontal cortical pyramidal neurons in schizophrenia | journal = Archives of General Psychiatry | volume = 57 | issue = 1 | pages = 65–73 | date = January 2000 | pmid = 10632234 | doi = 10.1001/archpsyc.57.1.65 | doi-access = }}</ref> <ref name="pmid10725376">{{cite journal | vauthors = Rodriguez MA, Pesold C, Liu WS, Kriho V, Guidotti A, Pappas GD, Costa E | title = Colocalization of integrin receptors and reelin in dendritic spine postsynaptic densities of adult nonhuman primate cortex | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 97 | issue = 7 | pages = 3550–5 | date = March 2000 | pmid = 10725376 | pmc = 16277 | doi = 10.1073/pnas.050589797 | bibcode = 2000PNAS...97.3550R | doi-access = free }}</ref> <ref name="pmid11592844">{{cite journal | vauthors = Costa E, Davis J, Grayson DR, Guidotti A, Pappas GD, Pesold C | title = Dendritic spine hypoplasticity and downregulation of reelin and GABAergic tone in schizophrenia vulnerability | journal = Neurobiology of Disease | volume = 8 | issue = 5 | pages = 723–42 | date = October 2001 | pmid = 11592844 | doi = 10.1006/nbdi.2001.0436 | s2cid = 31279244 | url = https://zenodo.org/record/1063618 }}</ref> <ref name="Kamnasaran_2003">{{cite journal | vauthors = Kamnasaran D, Muir WJ, Ferguson-Smith MA, Cox DW | title = Disruption of the neuronal PAS3 gene in a family affected with schizophrenia | journal = Journal of Medical Genetics | volume = 40 | issue = 5 | pages = 325–32 | date = May 2003 | pmid = 12746393 | pmc = 1735455 | doi = 10.1136/jmg.40.5.325 }}</ref> <ref name="Erbel-Sieler_NPAS3_deficient_mice_2004">{{cite journal | vauthors = Erbel-Sieler C, Dudley C, Zhou Y, Wu X, Estill SJ, Han T, Diaz-Arrastia R, Brunskill EW, Potter SS, McKnight SL | title = Behavioral and regulatory abnormalities in mice deficient in the NPAS1 and NPAS3 transcription factors | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 101 | issue = 37 | pages = 13648–53 | date = September 2004 | pmid = 15347806 | pmc = 518807 | doi = 10.1073/pnas.0405310101 | bibcode = 2004PNAS..10113648E | doi-access = free }}</ref> <ref name="pmid15979267">{{cite journal | vauthors = Chen Z, Schwahn BC, Wu Q, He X, Rozen R | title = Postnatal cerebellar defects in mice deficient in methylenetetrahydrofolate reductase | journal = International Journal of Developmental Neuroscience | volume = 23 | issue = 5 | pages = 465–74 | date = August 2005 | pmid = 15979267 | doi = 10.1016/j.ijdevneu.2005.05.007 | s2cid = 37922852 }}</ref> <ref name="GRIN2B_SZ_GENE_DB">[http://www.schizophreniaforum.org/res/sczgene/geneoverview.asp?geneid=135 Gene Overview of All Published Schizophrenia-Association Studies for GRIN2B] {{webarchive|url=https://web.archive.org/web/20100913030040/http://www.schizophreniaforum.org/res/sczgene/geneoverview.asp?geneid=135 |date=13 September 2010 }} – Schizophrenia Gene Database.</ref> <ref name="HRM_shared_abnormalities_with_SZ">{{cite journal | vauthors = Pappas GD, Kriho V, Pesold C | title = Reelin in the extracellular matrix and dendritic spines of the cortex and hippocampus: a comparison between wild type and heterozygous reeler mice by immunoelectron microscopy | journal = Journal of Neurocytology | volume = 30 | issue = 5 | pages = 413–25 | date = May 2001 | pmid = 11951052 | doi = 10.1023/A:1015017710332 | s2cid = 24887300 }}</ref> <ref name="HRM_not_SZ">{{cite journal | vauthors = Podhorna J, Didriksen M | title = The heterozygous reeler mouse: behavioural phenotype | journal = Behavioural Brain Research | volume = 153 | issue = 1 | pages = 43–54 | date = August 2004 | pmid = 15219705 | doi = 10.1016/j.bbr.2003.10.033 | s2cid = 538066 | doi-access = free }}</ref> <ref name="BipWoman09">{{cite journal | vauthors = Goes FS, Willour VL, Zandi PP, Belmonte PL, MacKinnon DF, Mondimore FM, Schweizer B, DePaulo JR, Gershon ES, McMahon FJ, Potash JB | title = Sex-specific association of the Reelin gene with bipolar disorder | journal = American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics | volume = 153B | issue = 2 | pages = 549–553 | date = March 2010 | pmid = 19691043 | pmc = 3032172 | doi = 10.1002/ajmg.b.31018 }}</ref> <ref name="pmid11317216">{{cite journal | vauthors = Persico AM, D'Agruma L, Maiorano N, Totaro A, Militerni R, Bravaccio C, Wassink TH, Schneider C, Melmed R, Trillo S, Montecchi F, Palermo M, Pascucci T, Puglisi-Allegra S, Reichelt KL, Conciatori M, Marino R, Quattrocchi CC, Baldi A, Zelante L, Gasparini P, Keller F | title = Reelin gene alleles and haplotypes as a factor predisposing to autistic disorder | journal = Molecular Psychiatry | volume = 6 | issue = 2 | pages = 150–9 | date = March 2001 | pmid = 11317216 | doi = 10.1038/sj.mp.4000850 | s2cid = 1472363 | doi-access = }}</ref> <ref name="pmid12399956">{{cite journal | vauthors = Zhang H, Liu X, Zhang C, Mundo E, Macciardi F, Grayson DR, Guidotti AR, Holden JJ | title = Reelin gene alleles and susceptibility to autism spectrum disorders | journal = Molecular Psychiatry | volume = 7 | issue = 9 | pages = 1012–7 | year = 2002 | pmid = 12399956 | doi = 10.1038/sj.mp.4001124 | s2cid = 30799924 | doi-access = }}</ref> <ref name="pmid14515139">{{cite journal | vauthors = Bonora E, Beyer KS, Lamb JA, Parr JR, Klauck SM, Benner A, Paolucci M, Abbott A, Ragoussis I, Poustka A, Bailey AJ, Monaco AP | title = Analysis of reelin as a candidate gene for autism | journal = Molecular Psychiatry | volume = 8 | issue = 10 | pages = 885–92 | date = October 2003 | pmid = 14515139 | doi = 10.1038/sj.mp.4001310 | s2cid = 32279857 | doi-access = }}</ref> <ref name="pmid15048647">{{cite journal | vauthors = Devlin B, Bennett P, Dawson G, Figlewicz DA, Grigorenko EL, McMahon W, Minshew N, Pauls D, Smith M, Spence MA, Rodier PM, Stodgell C, Schellenberg GD | title = Alleles of a reelin CGG repeat do not convey liability to autism in a sample from the CPEA network | journal = American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics | volume = 126B | issue = 1 | pages = 46–50 | date = April 2004 | pmid = 15048647 | doi = 10.1002/ajmg.b.20125 | s2cid = 14966506 | url = https://cloudfront.escholarship.org/dist/prd/content/qt7td237rb/qt7td237rb.pdf }}</ref> <ref name="pmid17919129">{{cite journal | vauthors = Pardo CA, Eberhart CG | title = The neurobiology of autism | journal = Brain Pathology | volume = 17 | issue = 4 | pages = 434–47 | date = October 2007 | pmid = 17919129 | doi = 10.1111/j.1750-3639.2007.00102.x | pmc = 8095519 | s2cid = 37048272 | doi-access = free }}</ref> <ref name="TLE1">{{cite journal | vauthors = Haas CA, Dudeck O, Kirsch M, Huszka C, Kann G, Pollak S, Zentner J, Frotscher M | title = Role for reelin in the development of granule cell dispersion in temporal lobe epilepsy | journal = The Journal of Neuroscience | volume = 22 | issue = 14 | pages = 5797–802 | date = July 2002 | pmid = 12122039 | pmc = 6757930 | doi = 10.1523/JNEUROSCI.22-14-05797.2002 }}</ref> <ref name="TLE2">{{cite journal | vauthors = Heinrich C, Nitta N, Flubacher A, Müller M, Fahrner A, Kirsch M, Freiman T, Suzuki F, Depaulis A, Frotscher M, Haas CA | title = Reelin deficiency and displacement of mature neurons, but not neurogenesis, underlie the formation of granule cell dispersion in the epileptic hippocampus | journal = The Journal of Neuroscience | volume = 26 | issue = 17 | pages = 4701–13 | date = April 2006 | pmid = 16641251 | pmc = 6674063 | doi = 10.1523/JNEUROSCI.5516-05.2006 }}</ref> <ref name="pmid19287316">{{cite journal | vauthors = Kobow K, Jeske I, Hildebrandt M, Hauke J, Hahnen E, Buslei R, Buchfelder M, Weigel D, Stefan H, Kasper B, Pauli E, Blümcke I | title = Increased reelin promoter methylation is associated with granule cell dispersion in human temporal lobe epilepsy | journal = Journal of Neuropathology and Experimental Neurology | volume = 68 | issue = 4 | pages = 356–64 | date = April 2009 | pmid = 19287316 | doi = 10.1097/NEN.0b013e31819ba737 | doi-access = free }}</ref> <ref name="Gonq_2007">{{cite journal | vauthors = Gong C, Wang TW, Huang HS, Parent JM | title = Reelin regulates neuronal progenitor migration in intact and epileptic hippocampus | journal = The Journal of Neuroscience | volume = 27 | issue = 8 | pages = 1803–11 | date = February 2007 | pmid = 17314278 | pmc = 6673551 | doi = 10.1523/JNEUROSCI.3111-06.2007 }}</ref> <ref name="pmid19185570">{{cite journal | vauthors = Müller MC, Osswald M, Tinnes S, Häussler U, Jacobi A, Förster E, Frotscher M, Haas CA | title = Exogenous reelin prevents granule cell dispersion in experimental epilepsy | journal = Experimental Neurology | volume = 216 | issue = 2 | pages = 390–7 | date = April 2009 | pmid = 19185570 | doi = 10.1016/j.expneurol.2008.12.029 | s2cid = 17173306 }}</ref> <ref name="alz">{{cite journal | vauthors = Botella-López A, Burgaya F, Gavín R, García-Ayllón MS, Gómez-Tortosa E, Peña-Casanova J, Ureña JM, Del Río JA, Blesa R, Soriano E, Sáez-Valero J | title = Reelin expression and glycosylation patterns are altered in Alzheimer's disease | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 103 | issue = 14 | pages = 5573–8 | date = April 2006 | pmid = 16567613 | pmc = 1414634 | doi = 10.1073/pnas.0601279103 | bibcode = 2006PNAS..103.5573B | doi-access = free }}</ref> <ref name="alzmouse">{{cite journal | vauthors = Wirths O, Multhaup G, Czech C, Blanchard V, Tremp G, Pradier L, Beyreuther K, Bayer TA | title = Reelin in plaques of beta-amyloid precursor protein and presenilin-1 double-transgenic mice | journal = Neuroscience Letters | volume = 316 | issue = 3 | pages = 145–8 | date = December 2001 | pmid = 11744223 | doi = 10.1016/S0304-3940(01)02399-0 | s2cid = 35475092 }}</ref> <ref name="pmid18599960">{{cite journal | vauthors = Seripa D, Matera MG, Franceschi M, Daniele A, Bizzarro A, Rinaldi M, Panza F, Fazio VM, Gravina C, D'Onofrio G, Solfrizzi V, Masullo C, Pilotto A | title = The RELN locus in Alzheimer's disease | journal = Journal of Alzheimer's Disease | volume = 14 | issue = 3 | pages = 335–44 | date = July 2008 | pmid = 18599960 | doi = 10.3233/jad-2008-14308 }}</ref> <ref name="pmid16051543">{{cite journal | vauthors = Baloyannis SJ | title = Morphological and morphometric alterations of Cajal-Retzius cells in early cases of Alzheimer's disease: a Golgi and electron microscope study | journal = The International Journal of Neuroscience | volume = 115 | issue = 7 | pages = 965–80 | date = July 2005 | pmid = 16051543 | doi = 10.1080/00207450590901396 | s2cid = 36197073 }}</ref> <ref name="pmid17453452">{{cite journal | vauthors = Baloyannis SJ, Costa V, Mauroudis I, Psaroulis D, Manolides SL, Manolides LS | title = Dendritic and spinal pathology in the acoustic cortex in Alzheimer's disease: morphological and morphometric estimation by Golgi technique and electron microscopy | journal = Acta Oto-Laryngologica | volume = 127 | issue = 4 | pages = 351–4 | date = April 2007 | pmid = 17453452 | doi = 10.1080/00016480601126986 | s2cid = 21625263 }}</ref> <ref name="pmid19515914">{{cite journal | vauthors = Hoe HS, Lee KJ, Carney RS, Lee J, Markova A, Lee JY, Howell BW, Hyman BT, Pak DT, Bu G, Rebeck GW | title = Interaction of reelin with amyloid precursor protein promotes neurite outgrowth | journal = The Journal of Neuroscience | volume = 29 | issue = 23 | pages = 7459–73 | date = June 2009 | pmid = 19515914 | pmc = 2759694 | doi = 10.1523/JNEUROSCI.4872-08.2009 }}</ref> <ref name="Herz2009relnabeta">{{cite journal | vauthors = Durakoglugil MS, Chen Y, White CL, Kavalali ET, Herz J | title = Reelin signaling antagonizes beta-amyloid at the synapse | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 106 | issue = 37 | pages = 15938–43 | date = September 2009 | pmid = 19805234 | pmc = 2747222 | doi = 10.1073/pnas.0908176106 | bibcode = 2009PNAS..10615938D | doi-access = free }}</ref> <ref name="Pancreatic_Cancer_2006">{{cite journal | vauthors = Sato N, Fukushima N, Chang R, Matsubayashi H, Goggins M | title = Differential and epigenetic gene expression profiling identifies frequent disruption of the RELN pathway in pancreatic cancers | journal = Gastroenterology | volume = 130 | issue = 2 | pages = 548–65 | date = February 2006 | pmid = 16472607 | doi = 10.1053/j.gastro.2005.11.008 | doi-access = free }}</ref> <ref name="Prostate_Cancer_2007_1">{{cite journal | vauthors = Perrone G, Vincenzi B, Zagami M, Santini D, Panteri R, Flammia G, Verzì A, Lepanto D, Morini S, Russo A, Bazan V, Tomasino RM, Morello V, Tonini G, Rabitti C | title = Reelin expression in human prostate cancer: a marker of tumor aggressiveness based on correlation with grade | journal = Modern Pathology | volume = 20 | issue = 3 | pages = 344–51 | date = March 2007 | pmid = 17277764 | doi = 10.1038/modpathol.3800743 | doi-access = free }}</ref> <ref name="pmid17615543">{{cite journal | vauthors = Seigel GM, Hackam AS, Ganguly A, Mandell LM, Gonzalez-Fernandez F | title = Human embryonic and neuronal stem cell markers in retinoblastoma | journal = Molecular Vision | volume = 13 | pages = 823–32 | date = June 2007 | pmid = 17615543 | pmc = 2768758 | url = http://www.molvis.org/molvis/v13/a90/ }}</ref> <ref name="pmid19230858">{{cite journal | vauthors = Schrauwen I, Ealy M, Huentelman MJ, Thys M, Homer N, Vanderstraeten K, Fransen E, Corneveaux JJ, Craig DW, Claustres M, Cremers CW, Dhooge I, Van de Heyning P, Vincent R, Offeciers E, Smith RJ, Van Camp G | title = A genome-wide analysis identifies genetic variants in the RELN gene associated with otosclerosis | journal = American Journal of Human Genetics | volume = 84 | issue = 3 | pages = 328–38 | date = March 2009 | pmid = 19230858 | pmc = 2667982 | doi = 10.1016/j.ajhg.2009.01.023 }}</ref> <ref name="pmid18062806">{{cite journal | vauthors = Delahaye NF, Coltel N, Puthier D, Barbier M, Benech P, Joly F, Iraqi FA, Grau GE, Nguyen C, Rihet P | title = Gene expression analysis reveals early changes in several molecular pathways in cerebral malaria-susceptible mice versus cerebral malaria-resistant mice | journal = BMC Genomics | volume = 8 | pages = 452 | date = December 2007 | pmid = 18062806 | pmc = 2246131 | doi = 10.1186/1471-2164-8-452 | doi-access = free }}</ref> <ref name="pmid15066269">{{cite journal | vauthors = Wang GS, Hong CJ, Yen TY, Huang HY, Ou Y, Huang TN, Jung WG, Kuo TY, Sheng M, Wang TF, Hsueh YP | title = Transcriptional modification by a CASK-interacting nucleosome assembly protein | journal = Neuron | volume = 42 | issue = 1 | pages = 113–28 | date = April 2004 | pmid = 15066269 | doi = 10.1016/S0896-6273(04)00139-4 | s2cid = 14383387 | doi-access = free }}</ref> <ref name="pmid16484373">{{cite journal | vauthors = Weaver IC, Meaney MJ, Szyf M | title = Maternal care effects on the hippocampal transcriptome and anxiety-mediated behaviors in the offspring that are reversible in adulthood | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 103 | issue = 9 | pages = 3480–5 | date = February 2006 | pmid = 16484373 | pmc = 1413873 | doi = 10.1073/pnas.0507526103 | bibcode = 2006PNAS..103.3480W | doi-access = free }}</ref> <ref name="pmid19357777">{{cite journal | vauthors = Smit-Rigter LA, Champagne DL, van Hooft JA | title = Lifelong impact of variations in maternal care on dendritic structure and function of cortical layer 2/3 pyramidal neurons in rat offspring | journal = PLOS ONE | volume = 4 | issue = 4 | pages = e5167 | year = 2009 | pmid = 19357777 | pmc = 2663818 | doi = 10.1371/journal.pone.0005167 | bibcode = 2009PLoSO...4.5167S | veditors = Linden R | doi-access = free }}</ref> <ref name="pmid19477232">{{cite journal | vauthors = Lussier AL, Caruncho HJ, Kalynchuk LE | title = Repeated exposure to corticosterone, but not restraint, decreases the number of reelin-positive cells in the adult rat hippocampus | journal = Neuroscience Letters | volume = 460 | issue = 2 | pages = 170–4 | date = August 2009 | pmid = 19477232 | doi = 10.1016/j.neulet.2009.05.050 | s2cid = 5305922 }}</ref> <ref name="pmid18757738">{{cite journal | vauthors = Dong E, Nelson M, Grayson DR, Costa E, Guidotti A | title = Clozapine and sulpiride but not haloperidol or olanzapine activate brain DNA demethylation | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 105 | issue = 36 | pages = 13614–9 | date = September 2008 | pmid = 18757738 | pmc = 2533238 | doi = 10.1073/pnas.0805493105 | bibcode = 2008PNAS..10513614D | doi-access = free }}</ref> <ref name="pmid19359144">{{cite journal | vauthors = Fatemi SH, Reutiman TJ, Folsom TD | title = Chronic psychotropic drug treatment causes differential expression of Reelin signaling system in frontal cortex of rats | journal = Schizophrenia Research | volume = 111 | issue = 1–3 | pages = 138–52 | date = June 2009 | pmid = 19359144 | doi = 10.1016/j.schres.2009.03.002 | s2cid = 37048872 }}</ref> <ref name="pmid12899622">{{cite journal | vauthors = Andersen OM, Benhayon D, Curran T, Willnow TE | title = Differential binding of ligands to the apolipoprotein E receptor 2 | journal = Biochemistry | volume = 42 | issue = 31 | pages = 9355–64 | date = August 2003 | pmid = 12899622 | doi = 10.1021/bi034475p }}</ref> <ref name="pmid12670700">{{cite journal | vauthors = Benhayon D, Magdaleno S, Curran T | title = Binding of purified Reelin to ApoER2 and VLDLR mediates tyrosine phosphorylation of Disabled-1 | journal = Brain Research. Molecular Brain Research | volume = 112 | issue = 1–2 | pages = 33–45 | date = April 2003 | pmid = 12670700 | doi = 10.1016/S0169-328X(03)00032-9 }}</ref> <ref name="pmid19922905">{{cite journal | vauthors = Wedenoja J, Tuulio-Henriksson A, Suvisaari J, Loukola A, Paunio T, Partonen T, Varilo T, Lönnqvist J, Peltonen L | title = Replication of association between working memory and Reelin, a potential modifier gene in schizophrenia | journal = Biological Psychiatry | volume = 67 | issue = 10 | pages = 983–91 | date = May 2010 | pmid = 19922905 | pmc = 3083525 | doi = 10.1016/j.biopsych.2009.09.026 }}</ref><ref name="pmid11252768">{{cite journal | vauthors = Herz J, Beffert U | title = Apolipoprotein E receptors: linking brain development and Alzheimer's disease | journal = Nature Reviews. Neuroscience | volume = 1 | issue = 1 | pages = 51–8 | date = October 2000 | pmid = 11252768 | doi = 10.1038/35036221 | s2cid = 27105032 }}</ref> <ref name="pmid17053810">{{cite journal | vauthors = Herz J, Chen Y | title = Reelin, lipoprotein receptors and synaptic plasticity | journal = Nature Reviews. Neuroscience | volume = 7 | issue = 11 | pages = 850–9 | date = November 2006 | pmid = 17053810 | doi = 10.1038/nrn2009 | s2cid = 44317115 }}</ref> <ref name="pmid20547867">{{cite journal | vauthors = Chen Y, Durakoglugil MS, Xian X, Herz J | title = ApoE4 reduces glutamate receptor function and synaptic plasticity by selectively impairing ApoE receptor recycling | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 107 | issue = 26 | pages = 12011–6 | date = June 2010 | pmid = 20547867 | pmc = 2900641 | doi = 10.1073/pnas.0914984107 | bibcode = 2010PNAS..10712011C | doi-access = free }}</ref> <ref name="pmid10571241">{{cite journal | vauthors = Hiesberger T, Trommsdorff M, Howell BW, Goffinet A, Mumby MC, Cooper JA, Herz J | title = Direct binding of Reelin to VLDL receptor and ApoE receptor 2 induces tyrosine phosphorylation of disabled-1 and modulates tau phosphorylation | journal = Neuron | volume = 24 | issue = 2 | pages = 481–9 | date = October 1999 | pmid = 10571241 | doi = 10.1016/S0896-6273(00)80861-2 | s2cid = 243043 | doi-access = free }}</ref> <ref name="pmid10571240">{{cite journal | vauthors = D'Arcangelo G, Homayouni R, Keshvara L, Rice DS, Sheldon M, Curran T | title = Reelin is a ligand for lipoprotein receptors | journal = Neuron | volume = 24 | issue = 2 | pages = 471–9 | date = October 1999 | pmid = 10571240 | doi = 10.1016/S0896-6273(00)80860-0 | s2cid = 14631418 | doi-access = free }}</ref> }}
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