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===Histopathology=== For a histopathological diagnosis, at least two of the following three criteria should be present:<ref>{{cite web | vauthors = Han L, Garcia R, Busca A, Parra-Herran C | date = November 2023 | veditors = Turashvili G, Skala SL | url = http://www.pathologyoutlines.com/topic/ovarynontumorendometriosis.html | title = Ovary - nontumor - Nonneoplastic cysts / other - Endometriosis | website = Pathology Outlines | access-date = 18 March 2020 | archive-date = 7 August 2020 | archive-url = https://web.archive.org/web/20200807014147/http://www.pathologyoutlines.com/topic/ovarynontumorendometriosis.html | url-status = live }}</ref> * Endometrial type [[stroma (animal tissue)|stroma]] * Endometrial [[epithelium]] with glands * Evidence of chronic hemorrhage, mainly [[hemosiderin]] deposits [[Immunohistochemistry]] is useful in diagnosing endometriosis as stromal cells have a peculiar surface antigen, CD10, thus allowing the pathologist go straight to a staining area and confirm the presence of stromal cells and sometimes glandular tissue is identified that was missed on routine [[H&E staining]].<ref>{{cite conference | vauthors = McMaster-Fay R, Osborn R, Chandraratnam E | title = The Clinical Utility Of CD10 Immunohistochemical Staining In The Diagnosis Of Endometriosis. | conference = 10th World Congress of Endometriosis | location = Melbourne, Australia. | url = http://www.rfay.com.au/docs/cd10poster.pdf |access-date=18 July 2013 |url-status=live |archive-url=https://web.archive.org/web/20130502131226/http://rfay.com.au/docs/cd10poster.pdf |archive-date=2 May 2013 }}</ref> <gallery mode="packed" heights="175"> File:Endometriosis, abdominal wall.jpg|Endometriosis, abdominal wall File:Endometriosis of the ovary.jpg|[[Micrograph]] showing endometriosis (right) and ovarian stroma (left) File:Endometrioma1.jpg|[[Micrograph]] of the wall of an endometrioma. All features of endometriosis are present (endometrial [[gland]]s, endometrial [[stroma (animal tissue)|stroma]] and [[hemosiderin]]-laden [[macrophage]]s). </gallery>
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