Editing Proteasome (section)

==== UCH37 ====
UCH37 is a Ubiquitin C-terminal hydrolase that activated upon binding the 26S proteasome through the ubiquitin receptor Rpn13.<ref>{{cite journal |last1=Yao |first1=Tingting |last2=Song |first2=Ling |last3=Xu |first3=Wei |last4=DeMartino |first4=George N. |last5=Florens |first5=Laurence |last6=Swanson |first6=Selene K. |last7=Washburn |first7=Michael P. |last8=Conaway |first8=Ronald C. |last9=Conaway |first9=Joan Weliky |last10=Cohen |first10=Robert E. |title=Proteasome recruitment and activation of the Uch37 deubiquitinating enzyme by Adrm1 |journal=Nature Cell Biology |date=September 2006 |volume=8 |issue=9 |pages=994–1002 |doi=10.1038/ncb1460 |pmid=16906146 }}</ref>  UCH37 is activated upon binding the proteasome through the C-terminal DEUBAD (DUB adaptor) domain that binds Rpn2.<ref>{{cite journal |last1=VanderLinden |first1=Ryan T. |last2=Hemmis |first2=Casey W. |last3=Schmitt |first3=Benjamin |last4=Ndoja |first4=Ada |last5=Whitby |first5=Frank G. |last6=Robinson |first6=Howard |last7=Cohen |first7=Robert E. |last8=Yao |first8=Tingting |last9=Hill |first9=Christopher P. |title=Structural Basis for the Activation and Inhibition of the UCH37 Deubiquitylase |journal=Molecular Cell |date=5 March 2015 |volume=57 |issue=5 |pages=901–911 |doi=10.1016/j.molcel.2015.01.016 |pmid=25702872 |pmc=4355076 }}</ref><ref>{{cite journal |last1=Sahtoe |first1=DD |last2=van Dijk |first2=WJ |last3=El Oualid |first3=F |last4=Ekkebus |first4=R |last5=Ovaa |first5=H |last6=Sixma |first6=TK |title=Mechanism of UCH-L5 activation and inhibition by DEUBAD domains in RPN13 and INO80G. |journal=Molecular Cell |date=5 March 2015 |volume=57 |issue=5 |pages=887–900 |doi=10.1016/j.molcel.2014.12.039 |pmid=25702870|pmc=4352763 }}</ref>