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===Medications=== [[Pharmacological]] treatments can help people control their sexual behaviors, but do not change the content of the paraphilia.<ref name="thibaut2010"/> They are typically combined with [[cognitive behavioral therapy]] for best effect.<ref name="assumpcao2014">{{cite journal|last1=Assumpção|first1=Alessandra Almeida|last2=Garcia|first2=Frederick Duarte|last3=Garcia|first3=Heloise Delavenne|last4=Bradford|first4=John M.W.|last5=Thibaut|first5=Florence|title=Pharmacologic treatment of paraphilias|journal=[[Psychiatric Clinics of North America]]|publisher=[[Elsevier]]|location=Amsterdam, Netherlands|volume=37|issue=2|pages=173–181|date=June 2014|pmid=24877704|doi=10.1016/j.psc.2014.03.002}}</ref> ====SSRIs==== [[Selective serotonin reuptake inhibitor]]s (SSRIs) have been well received and are considered an important pharmacological treatment of severe paraphilic disorders.<ref>{{Cite journal|last1=Kraus|first1=Christoph|last2=Strohm|first2=Kate|last3=Hill|first3=Andrew|last4=Habermann|first4=Niels|last5=Berner|first5=Wolfgang|last6=Briken|first6=Peer|date=June 2007|title=Selective serotonine reuptake inhibitors (SSRI) in the treatment of paraphilia|journal=Fortschritte der Neurologie-Psychiatrie|location=Melbourne, Australia|publisher=[[University of Melbourne]]|volume=75|issue=6|pages=351–356|doi=10.1055/s-2006-944261|issn=0720-4299|pmid=17031776}}</ref> They are proposed to work by reducing sexual arousal, [[compulsivity]], and depressive symptoms. They have been used with exhibitionists, non-offending pedophiles, and compulsive masturbators.<ref name="assumpcao2014"/> ====Antiandrogens==== [[Antiandrogen]]s are used in more extreme cases.<ref name="assumpcao2014"/> Similar to physical [[castration]], they work by reducing [[androgen]] levels, and have thus been described as [[chemical castration]].<ref name="assumpcao2014"/> The antiandrogen [[cyproterone acetate]] has been shown to substantially reduce sexual fantasies and offending behaviors.<ref name="assumpcao2014"/> [[Medroxyprogesterone acetate]] and [[gonadotropin-releasing hormone agonist]]s (such as [[leuprorelin]]) have also been used to lower sex drive.<ref name="assumpcao2014"/> Due to the side effects, the World Federation of Societies of Biological Psychiatry recommends that hormonal treatments only be used when there is a serious risk of sexual violence, or when other methods have failed.<!-- p. 647 --><ref name="thibaut2010">{{cite journal|vauthors=Thibaut F, De La Barra F, Gordon H, Cosyns P, Bradford JM|title=The World Federation of Societies of Biological Psychiatry (WFSBP) guidelines for the biological treatment of paraphilias|journal=The World Journal of Biological Psychiatry|volume=11|issue=4|pages=604–655|year=2010|pmid=20459370|doi=10.3109/15622971003671628|s2cid=14949511}}</ref> Surgical [[castration]] has largely been abandoned because these pharmacological alternatives are similarly effective and less invasive.<ref>{{cite book|first=Michael C.|last=Seto|authorlink=Michael C. Seto|date=2008|title=Sexual Deviance: Theory, Assessment, and Treatment|edition=2nd|publisher=[[The Guilford Press]]|location=New York City|pages=199–200|chapter=Pedophilia: Assessment and Treatment|editor1-first=D. Richard|editor1-last=Laws|editor2-first=William T.|editor2-last=O'Donohue}}</ref>
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