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==Other animals== A neuroendocrine system has been observed in all [[animal]]s with a nervous system and all [[vertebrate]]s have a hypothalamus–pituitary axis.<ref>{{cite journal |vauthors=Hartenstein V |title=The neuroendocrine system of invertebrates: a developmental and evolutionary perspective |journal=The Journal of Endocrinology |volume=190 |issue=3 |pages=555–70 |date=September 2006 |pmid=17003257 |doi=10.1677/joe.1.06964 |doi-access=free}}</ref> All vertebrates have a thyroid, which in [[amphibian]]s is also crucial for transformation of larvae into adult form.<ref>{{cite journal |first1=Walton W. |last1=Dickhoff |first2=Douglas S. |last2=Darling |name-list-style=vanc |year=1983 |title=Evolution of Thyroid Function and Its Control in Lower Vertebrates |journal=American Zoologist |volume=23 |issue=3 |pages=697–707 |jstor=3882951 |doi=10.1093/icb/23.3.697|doi-access=free}}</ref><ref>{{cite journal |last=Galton |first=Valerie Anne |name-list-style=vanc |title=The Role of Thyroid Hormone in Amphibian Development |journal=Integrative and Comparative Biology |date=January 1, 1988 |volume=28 |issue=2 |pages=309–18 |jstor=3883279 |doi=10.1093/icb/28.2.309|doi-access=free}}</ref> All vertebrates have adrenal gland tissue, with mammals unique in having it organized into layers.<ref>{{cite journal |vauthors=Pohorecky LA, Wurtman RJ |title=Adrenocortical control of epinephrine synthesis |journal=Pharmacological Reviews |volume=23 |issue=1 |pages=1–35 |date=March 1971 |doi=10.1016/S0031-6997(25)06886-3 |pmid=4941407}}</ref> All vertebrates have some form of a renin–angiotensin axis, and all [[tetrapods]] have aldosterone as a primary [[mineralocorticoid]].<ref>{{cite journal |vauthors=Wilson JX |title=The renin-angiotensin system in nonmammalian vertebrates |journal=Endocrine Reviews |volume=5 |issue=1 |pages=45–61 |year=1984 |pmid=6368215 |doi=10.1210/edrv-5-1-45}}</ref><ref>{{cite journal |vauthors=Colombo L, Dalla Valle L, Fiore C, Armanini D, Belvedere P |title=Aldosterone and the conquest of land |journal=Journal of Endocrinological Investigation |volume=29 |issue=4 |pages=373–9 |date=April 2006 |pmid=16699307 |doi=10.1007/bf03344112 |s2cid=25316873}}</ref>
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