Editing Coenzyme Q10 (section)

==History==
In 1950, a small amount of CoQ<sub>10</sub> was isolated from the lining of a horse's gut, a compound initially called ''substance SA'', but later deemed to be quinone found in many animal tissues.<ref name="pmid13622652">{{cite journal | vauthors = Morton RA | title = Ubiquinone | journal = Nature | volume = 182 | issue = 4652 | pages = 1764–1767 | date = December 1958 | pmid = 13622652 | doi = 10.1038/1821764a0 | bibcode = 1958Natur.182.1764M }}</ref> In 1957, the same compound was isolated from [[mitochondria]]l membranes of beef heart, with research showing that it transported electrons within mitochondria. It was called ''Q-275'' as a quinone.<ref name="pmid13622652"/><ref name="pmid13445756">{{cite journal | vauthors = Crane FL, Hatefi Y, Lester RL, Widmer C | title = Isolation of a quinone from beef heart mitochondria | journal = Biochimica et Biophysica Acta | volume = 25 | issue = 1 | pages = 220–221 | date = July 1957 | pmid = 13445756 | doi = 10.1016/0006-3002(57)90457-2 }}</ref> The Q-275/substance SA was later renamed ''ubiquinone'' as it was a ''ubiquitous'' quinone found in all animal tissues.<ref name="pmid13622652"/> In 1958, its full chemical structure was reported.<ref name="pmid13622652"/><ref name="Wolf-1958">{{Cite journal|vauthors=Wolf DE|date=1958|title=Coenzyme Q. I. structure studies on the coenzyme Q group|journal=Journal of the American Chemical Society|volume= 80|issue=17|page=4752|doi=10.1021/ja01550a096|bibcode=1958JAChS..80.4752W |issn=0002-7863}}</ref> Ubiquinone was later called either ''mitoquinone'' or ''coenzyme Q'' due to its participation to the mitochondrial electron transport chain.<ref name="pmid13622652"/> In 1966, a study reported that reduced CoQ<sub>6</sub> was an effective [[antioxidant]] in cells.<ref name="pmid17805631">{{cite journal | vauthors = Mellors A, Tappel AL | title = Quinones and quinols as inhibitors of lipid peroxidation | journal = Lipids | volume = 1 | issue = 4 | pages = 282–284 | date = July 1966 | pmid = 17805631 | doi = 10.1007/BF02531617 | s2cid = 2129339 }}</ref>