Editing Chemotherapy (section)

=== Tumor lysis syndrome ===
In particularly large tumors and cancers with high [[white cell count]]s, such as [[lymphoma]]s, [[teratoma]]s, and some [[leukemia]]s, some people develop [[tumor lysis syndrome]]. The rapid breakdown of cancer cells causes the release of chemicals from the inside of the cells. Following this, high levels of [[hyperuricemia|uric acid]], [[hyperkalemia|potassium]] and [[hyperphosphatemia|phosphate]] are found in the blood. High levels of phosphate induce secondary hypoparathyroidism, resulting in low levels of calcium in the blood.<ref>{{Citation |last1=Adeyinka |first1=Adebayo |title=Tumor Lysis Syndrome |date=2022 |url=http://www.ncbi.nlm.nih.gov/books/NBK518985/ |work=StatPearls |place=Treasure Island (FL) |publisher=StatPearls Publishing |pmid=30085527 |access-date=2022-11-08 |last2=Bashir |first2=Khalid}}</ref> This causes kidney damage and the high levels of potassium can cause [[Cardiac dysrhythmia|cardiac arrhythmia]]. Although prophylaxis is available and is often initiated in people with large tumors, this is a dangerous side-effect that can lead to death if left untreated.<ref name=Wood2005/>{{rp|202}}