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==== Phenotyping and endotyping ==== {{Main|Asthma phenotyping and endotyping}} Asthma phenotyping and endotyping has emerged as a novel approach to asthma classification inspired by [[precision medicine]] which separates the clinical presentations of asthma, or asthma phenotypes, from their underlying causes, or asthma endotypes. The best-supported endotypic distinction is the type 2-high/type 2-low distinction. Classification based on type 2 inflammation is useful in predicting which patients will benefit from targeted [[biologic therapy]].<ref>{{cite journal | vauthors = Kuruvilla ME, Lee FE, Lee GB | title = Understanding Asthma Phenotypes, Endotypes, and Mechanisms of Disease | journal = Clinical Reviews in Allergy & Immunology | volume = 56 | issue = 2 | pages = 219β233 | date = April 2019 | pmid = 30206782 | pmc = 6411459 | doi = 10.1007/s12016-018-8712-1 }}</ref><ref>{{cite journal | vauthors = Ray A, Camiolo M, Fitzpatrick A, Gauthier M, Wenzel SE | title = Are We Meeting the Promise of Endotypes and Precision Medicine in Asthma? | journal = Physiological Reviews | volume = 100 | issue = 3 | pages = 983β1017 | date = July 2020 | pmid = 31917651 | pmc = 7474260 | doi = 10.1152/physrev.00023.2019 }}</ref>
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