Editing Polycystic ovary syndrome (section)

=== Alternative medicine ===
A 2017 review concluded that while both myo-inositol and D-chiro-inositols may regulate menstrual cycles and improve ovulation, there is a lack of evidence regarding effects on the probability of pregnancy.<ref>{{cite journal | vauthors = Pundir J, Psaroudakis D, Savnur P, Bhide P, Sabatini L, Teede H, Coomarasamy A, Thangaratinam S | title = Inositol treatment of anovulation in women with polycystic ovary syndrome: a meta-analysis of randomised trials | journal = BJOG | volume = 125 | issue = 3 | pages = 299–308 | date = February 2018 | pmid = 28544572 | doi = 10.1111/1471-0528.14754 | s2cid = 21090113 | url = https://pure-oai.bham.ac.uk/ws/files/41620024/Pundir_et_al_Inositol_treatment_BJOG.pdf | access-date = 13 October 2021 | archive-date = 24 October 2021 | archive-url = https://web.archive.org/web/20211024092854/http://pure-oai.bham.ac.uk/ws/files/41620024/Pundir_et_al_Inositol_treatment_BJOG.pdf | url-status = live }}</ref><ref>{{cite journal | vauthors = Amoah-Arko A, Evans M, Rees A |title=Effects of myoinositol and D-chiro inositol on hyperandrogenism and ovulation in women with polycystic ovary syndrome: a systematic review |journal=Endocrine Abstracts |date=20 October 2017 |doi=10.1530/endoabs.50.P363 }}</ref> A 2012 and 2017 review have found [[myo-inositol]] supplementation appears to be effective in improving several of the hormonal disturbances of PCOS.<ref name="pmid22296306">{{cite journal | vauthors = Unfer V, Carlomagno G, Dante G, Facchinetti F | title = Effects of myo-inositol in women with PCOS: a systematic review of randomized controlled trials | journal = Gynecological Endocrinology | volume = 28 | issue = 7 | pages = 509–515 | date = July 2012 | pmid = 22296306 | doi = 10.3109/09513590.2011.650660 | s2cid = 24582338 }}</ref><ref>{{cite journal | vauthors = Zeng L, Yang K | title = Effectiveness of myoinositol for polycystic ovary syndrome: a systematic review and meta-analysis | journal = Endocrine | volume = 59 | issue = 1 | pages = 30–38 | date = January 2018 | pmid = 29052180 | doi = 10.1007/s12020-017-1442-y | s2cid = 4376339 }}</ref> Myo-inositol reduces the amount of gonadotropins and the length of controlled ovarian hyperstimulation in women undergoing in vitro fertilization.<ref>{{cite journal | vauthors = Laganà AS, Vitagliano A, Noventa M, Ambrosini G, D'Anna R | title = Myo-inositol supplementation reduces the amount of gonadotropins and length of ovarian stimulation in women undergoing IVF: a systematic review and meta-analysis of randomized controlled trials | journal = Archives of Gynecology and Obstetrics | volume = 298 | issue = 4 | pages = 675–684 | date = October 2018 | pmid = 30078122 | doi = 10.1007/s00404-018-4861-y | s2cid = 51921158 }}</ref> A 2011 review found not enough evidence to conclude any beneficial effect from [[D-chiro-inositol]].<ref name="pmid21142777">{{cite journal | vauthors = Galazis N, Galazi M, Atiomo W | title = D-Chiro-inositol and its significance in polycystic ovary syndrome: a systematic review | journal = Gynecological Endocrinology | volume = 27 | issue = 4 | pages = 256–262 | date = April 2011 | pmid = 21142777 | doi = 10.3109/09513590.2010.538099 | s2cid = 1989262 }}</ref> There is insufficient evidence to support the use of [[acupuncture]], current studies are inconclusive and there's a need for additional [[randomized controlled trial]]s.<ref>{{cite journal | vauthors = Lim CE, Ng RW, Cheng NC, Zhang GS, Chen H | title = Acupuncture for polycystic ovarian syndrome | journal = The Cochrane Database of Systematic Reviews | volume = 2019 | pages = CD007689 | date = July 2019 | issue = 7 | pmid = 31264709 | pmc = 6603768 | doi = 10.1002/14651858.CD007689.pub4 }}</ref><ref>{{cite journal | vauthors = Wu XK, Stener-Victorin E, Kuang HY, Ma HL, Gao JS, Xie LZ, Hou LH, Hu ZX, Shao XG, Ge J, Zhang JF, Xue HY, Xu XF, Liang RN, Ma HX, Yang HW, Li WL, Huang DM, Sun Y, Hao CF, Du SM, Yang ZW, Wang X, Yan Y, Chen XH, Fu P, Ding CF, Gao YQ, Zhou ZM, Wang CC, Wu TX, Liu JP, Ng EH, Legro RS, Zhang H | title = Effect of Acupuncture and Clomiphene in Chinese Women With Polycystic Ovary Syndrome: A Randomized Clinical Trial | journal = JAMA | volume = 317 | issue = 24 | pages = 2502–14 | date = June 2017 | pmid = 28655015 | pmc = 5815063 | doi = 10.1001/jama.2017.7217 }}</ref>