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=== 2010 hip-replacement recall === {{Main|2010 DePuy Hip Recall}} On August 24, 2010, DePuy, a subsidiary of American giant Johnson & Johnson, recalled its ASR (articular surface replacement) hip prostheses from the market. DePuy said the recall was due to unpublished National Joint Registry data showing a 12% revision rate for resurfacing at five years and an ASR XL revision rate of 13%. All hip prostheses fail in some patients, but it is expected that the rate will be about 1% a year.<ref name="Out of joint">{{Cite news | url = http://www.bmj.com/content/342/bmj.d2905.full | title = Out of joint: The story of the ASR | date = May 14, 2011 | author=Deborah Cohen }}</ref> Pathologically, the failing prosthesis had several effects. Metal debris from wear of the implant led to a reaction that destroyed the soft tissues surrounding the joint, leaving some patients with long term disability. Ions of cobalt and chromium{{snd}}the metals from which the implant was made{{snd}}were also released into the blood and [[cerebrospinal fluid]] in some patients.<ref name="fda1">{{Cite news | url = https://www.fda.gov/MedicalDevices/ProductsandMedicalProcedures/ImplantsandProsthetics/MetalonMetalHipImplants/ucm241604.htm | title = FDA. Concerns about metal-on-metal hip implant systems. 2011 | year = 2011 }}</ref> In March 2013, a jury in Los Angeles ordered Johnson & Johnson to pay more than $8.3{{nbs}}million in damages to a Montana man in the first of more than 10,000 lawsuits pending against the company in connection with the now-recalled DePuy hip.<ref name="Meier">{{Cite news| vauthors = Meier B |title=J.&J. Loses First Case Over Faulty Hip Implant|url=https://www.nytimes.com/2013/03/09/business/johnson-johnson-must-pay-in-first-hip-implant-case.html|access-date=September 4, 2013|newspaper=[[The New York Times]]|date=March 8, 2013}}</ref> Some lawyers and industry analysts have estimated that the suits ultimately will cost Johnson & Johnson billions of dollars to resolve.<ref name="Meier"/>
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