Editing Insulin (section)

==== Controversy ====
[[File:Nicolae Paulescu - Foto03.jpg|thumb|upright=0.65|[[Nicolae Paulescu]]]]

The work published by Banting, Best, Collip and Macleod represented the preparation of purified insulin extract suitable for use on human patients.<ref name="pmid20314060">{{cite journal | vauthors = Banting FG, Best CH, Collip JB, Campbell WR, Fletcher AA | title = Pancreatic Extracts in the Treatment of Diabetes Mellitus | journal = Canadian Medical Association Journal | volume = 12 | issue = 3 | pages = 141–46 | date = March 1922 | pmid = 20314060 | pmc = 1524425 }}</ref> Although Paulescu discovered the principles of the treatment, his saline extract could not be used on humans; he was not mentioned in the 1923 Nobel Prize. Ian Murray was particularly active in working to correct "the historical wrong" against [[Nicolae Paulescu]]. Murray was a professor of physiology at the Anderson College of Medicine in [[Glasgow]], [[Scotland]], the head of the department of Metabolic Diseases at a leading Glasgow hospital, vice-president of the British Association of Diabetes, and a founding member of the [[International Diabetes Federation]]. Murray wrote:

{{blockquote|Insufficient recognition has been given to Paulescu, the distinguished [[Romania]]n scientist, who at the time when the Toronto team were commencing their research had already succeeded in extracting the antidiabetic hormone of the pancreas and proving its efficacy in reducing the hyperglycaemia in diabetic dogs.<ref name="pmid4560502">{{cite journal | vauthors = Drury MI | title = The golden jubile of insulin | journal = Journal of the Irish Medical Association | volume = 65 | issue = 14 | pages = 355–63 | date = July 1972 | pmid = 4560502 }}</ref>
}}

In a private communication, [[Arne Tiselius]], former head of the Nobel Institute, expressed his personal opinion that Paulescu was equally worthy of the award in 1923.<ref name="pmid4930788">{{cite journal | vauthors = Murray I | title = Paulesco and the isolation of insulin | journal = Journal of the History of Medicine and Allied Sciences | volume = 26 | issue = 2 | pages = 150–57 | date = April 1971 | pmid = 4930788 | doi = 10.1093/jhmas/XXVI.2.150 }}</ref>