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=== Surgery === Cirrhosis due to hepatitis C is a common reason for [[liver transplant]]ation,<ref name=Tah2009>{{cite journal | vauthors = Ozaras R, Tahan V | title = Acute hepatitis C: prevention and treatment | journal = Expert Review of Anti-Infective Therapy | volume = 7 | issue = 3 | pages = 351β61 | date = April 2009 | pmid = 19344247 | doi = 10.1586/eri.09.8 | s2cid = 25574917 }}</ref> though the virus usually (80β90% of cases) recurs afterwards.<ref name=NEJM2011 /><ref>{{cite book| vauthors = Sanders M |title=Mosby's Paramedic Textbook|year=2011|publisher=Jones & Bartlett Publishers|isbn=978-0-323-07275-5|page=839|url=https://books.google.com/books?id=PJyhIH8N8qgC&pg=PA839|url-status=live|archive-url=https://web.archive.org/web/20160511134533/https://books.google.com/books?id=PJyhIH8N8qgC&pg=PA839|archive-date=2016-05-11}}</ref> Infection of the graft leads to 10β30% of people developing cirrhosis within five years.<ref name=Ciria2013>{{cite journal | vauthors = Ciria R, Pleguezuelo M, Khorsandi SE, Davila D, Suddle A, Vilca-Melendez H, Rufian S, de la Mata M, BriceΓ±o J, Cillero PL, Heaton N | display-authors = 6 | title = Strategies to reduce hepatitis C virus recurrence after liver transplantation | journal = World Journal of Hepatology | volume = 5 | issue = 5 | pages = 237β50 | date = May 2013 | pmid = 23717735 | pmc = 3664282 | doi = 10.4254/wjh.v5.i5.237 | doi-access = free }}</ref> Treatment with pegylated interferon and ribavirin post-transplant decreases the risk of recurrence to 70%.<ref name=Coilly2013>{{cite journal | vauthors = Coilly A, Roche B, Samuel D | title = Current management and perspectives for HCV recurrence after liver transplantation | journal = Liver International | volume = 33 | pages = 56β62 | date = February 2013 | issue = Suppl 1 | pmid = 23286847 | doi = 10.1111/liv.12062 | s2cid = 23601091 | doi-access = free }}</ref> A 2013 review found no clear evidence as to whether antiviral medication is useful if the graft became reinfected.<ref>{{cite journal | vauthors = Gurusamy KS, Tsochatzis E, Toon CD, Xirouchakis E, Burroughs AK, Davidson BR | title = Antiviral interventions for liver transplant patients with recurrent graft infection due to hepatitis C virus | journal = The Cochrane Database of Systematic Reviews | issue = 12 | pages = CD006803 | date = December 2013 | volume = 2014 | pmid = 24307460 | doi = 10.1002/14651858.CD006803.pub4 | pmc = 8930021 }}</ref>
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