Editing Buckminsterfullerene (section)

==Potential applications in health==
{{Main|Health and safety hazards of nanomaterials|Toxicology of carbon nanomaterials}}
=== Ingestion and risks ===
C<sub>60</sub> is sensitive to light,<ref name=":2" /> so leaving C<sub>60</sub> under light exposure causes it to degrade, becoming dangerous. The ingestion of C<sub>60</sub> solutions that have been exposed to light could lead to developing cancer (tumors).<ref name=":3">{{Cite web|last=Grohn, Kristopher J.|title=Comp grad leads research|url=http://weyburnreview.com/news/local-news/comp-grad-leads-research-1.2261882|url-status=live|website=WeyburnReview |access-date=2021-04-17|archive-date=2021-04-17|archive-url=https://web.archive.org/web/20210417041410/https://www.weyburnreview.com/news/local-news/comp-grad-leads-research-1.2261882}}</ref><ref name=":1" /> So the management of C<sub>60</sub> products for human ingestion requires cautionary measures<ref name=":1" /> such as: elaboration in very dark environments, encasing into bottles of great opacity, and storing in dark places, and others like consumption under low light conditions and using labels to warn about the problems with light.

Solutions of C<sub>60</sub> dissolved in olive oil or water, as long as they are preserved from light, have been found nontoxic to rodents.<ref name=":0">{{cite journal|last1=Baati|first1=Tarek|last2=Moussa|first2=Fathi|date=June 2012|title=The prolongation of the lifespan of rats by repeated oral administration of [60]fullerene|journal=Biomaterials|volume=33|issue=19|pages=4936–4946|doi=10.1016/j.biomaterials.2012.03.036|pmid=22498298}}<!--|access-date=June 2012--></ref>

Otherwise, a study found that C<sub>60</sub> remains in the body for a longer time than usual, especially in the liver, where it tends to be accumulated, and therefore has the potential to induce detrimental health effects.<ref>{{cite journal | pmc=7005847 | year=2019 | last1=Shipkowski | first1=K. A. | last2=Sanders | first2=J. M. | last3=McDonald | first3=J. D. | last4=Walker | first4=N. J. | last5=Waidyanatha | first5=S. | title=Disposition of fullerene C60 in rats following intratracheal or intravenous administration | journal=Xenobiotica; the Fate of Foreign Compounds in Biological Systems | volume=49 | issue=9 | pages=1078–1085 | doi=10.1080/00498254.2018.1528646 | pmid=30257131}}</ref>

=== Oils with C60 and risks ===
An experiment in 2011–2012 administered a solution of C<sub>60</sub> in olive oil to rats, achieving a 90% prolongation of their lifespan.<ref name=":0" /> C<sub>60</sub> in olive oil administered to mice resulted in no extension in lifespan.<ref name="pmid33123847">{{cite journal | vauthors=Grohn KJ, Moyer BS, Moody KJ | title=C60 in olive oil causes light-dependent toxicity and does not extend lifespan in mice | journal=[[GeroScience]] | volume=49 | issue=2 | pages=579-591 | year=2021 |  doi = 10.1007/s11357-020-00292-z | pmc=8110650 | pmid=33123847 | doi-access=free }}</ref> C<sub>60</sub> in olive oil administered to [[Beagle|beagle dogs]] resulted in a large reduction of [[C-reactive protein]], which is commonly elevated in [[cardiovascular disease]] and [[cerebrovascular disease]].<ref name="pmid36643955">{{cite journal | vauthors=Hui M, Jia X, Shi M | title=Anti-Inflammatory and Antioxidant Effects of Liposoluble C60 at the Cellular, Molecular, and Whole-Animal Levels| journal=[[Journal of Inflammation Research]] | volume=16 |  pages=83-89 | year=2023 |  doi = 10.2147/JIR.S386381 | pmc=8110650 | pmid=36643955 | doi-access=free }}</ref> 

Many oils with C<sub>60</sub> have been sold as antioxidant products, but it does not avoid the problem of their sensitivity to light, that can turn them toxic. A later research confirmed that exposure to light degrades solutions of C<sub>60</sub> in oil, making it toxic and leading to a "massive" increase of the risk of developing cancer (tumors) after its consumption.<ref name=":3" /><ref name=":1">{{Cite web|last=Grohn |first=Kristopher J. |display-authors=etal |title=C60 in olive oil causes light-dependent toxicity|url-status=live |url=https://gwern.net/docs/longevity/2020-grohn.pdf|access-date=2021-04-15|archive-date=2021-04-15|archive-url=https://web.archive.org/web/20210415212442/https://www.gwern.net/docs/longevity/2020-grohn.pdf}}</ref>

To avoid the degradation by effect of light, C<sub>60</sub> oils must be made in very dark environments, encased into bottles of great opacity, and kept in darkness, consumed under low light conditions and accompanied by labels to warn about the dangers of light for C<sub>60</sub>.<ref name=":1"/><ref name=":2">{{Cite magazine|magazine=Nature|title=Degradation of C60 by light|date=23 May 1991|volume=351 |url=https://nature.com/articles/351277a0.pdf|author-first1=Roger|author-first2=Jonathan P. |author-first3=Anthony G. |author-first4=Steven P. |author-first5=T. John|author-first6=Jonathan P. |author-first7=Harold W. |author-first8=David R. M. |author-last1=Taylor|author-last2=Parsons|author-last3=Avent|author-last4=Rannard|author-last5=Dennis|author-last6=Hare|author-last7=Kroto|author-last8=Walton}}</ref>

Some producers have been able to dissolve C<sub>60</sub> in water to avoid possible problems with oils, but that would not protect C<sub>60</sub> from light, so the same cautions are needed.<ref name=":2" />