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===Clinical research=== There is no conclusive evidence that thalidomide or [[lenalidomide]] is useful to bring about or maintain remission in Crohn's disease.<ref>{{Cite journal |vauthors=Srinivasan R, Akobeng AK |date=April 2009 |title=Thalidomide and thalidomide analogues for induction of remission in Crohn's disease |journal=The Cochrane Database of Systematic Reviews |issue=2 |pages=CD007350 |doi=10.1002/14651858.CD007350.pub2 |pmid=19370684}}</ref><ref>{{Cite journal |vauthors=Akobeng AK, Stokkers PC |date=April 2009 |title=Thalidomide and thalidomide analogues for maintenance of remission in Crohn's disease |journal=The Cochrane Database of Systematic Reviews |volume=2009 |issue=2 |pages=CD007351 |doi=10.1002/14651858.CD007351.pub2 |pmc=7207562 |pmid=19370685}}</ref> Thalidomide was studied in a Phase II trial for [[Kaposi's sarcoma]], a rare soft-tissue cancer most commonly seen in the immunocompromised, that is caused by the [[Kaposi's sarcoma-associated herpesvirus]] (KSHV).<ref>{{Cite web |date=11 March 2013 |title=Kaposi Sarcoma Treatment & Management |url=http://emedicine.medscape.com/article/279734-treatment#showall |url-status=live |archive-url=https://web.archive.org/web/20140202145013/http://emedicine.medscape.com/article/279734-treatment#showall |archive-date=2 February 2014 |access-date=19 January 2014 |website=Medscape Reference |publisher=WebMD |vauthors=Rose LJ, Fishman AD, Sparano JA |veditors=Talavera F, McKenna R, Harris JE}}</ref><ref name="pmid15172781" /> {{Div col}} * AIDS wasting syndrome,<ref>{{Cite journal |vauthors=Gordon JN, Trebble TM, Ellis RD, Duncan HD, Johns T, Goggin PM |date=April 2005 |title=Thalidomide in the treatment of cancer cachexia: a randomised placebo controlled trial |journal=Gut |volume=54 |issue=4 |pages=540β5 |doi=10.1136/gut.2004.047563 |pmc=1774430 |pmid=15753541}}</ref> associated diarrhea<ref>{{Cite journal |vauthors=Sharpstone D, Rowbottom A, Francis N, Tovey G, Ellis D, Barrett M, Gazzard B |date=June 1997 |title=Thalidomide: a novel therapy for microsporidiosis |journal=Gastroenterology |volume=112 |issue=6 |pages=1823β9 |doi=10.1053/gast.1997.v112.pm9178672 |pmid=9178672 |doi-access=free}}</ref> * [[Renal cell carcinoma]] (RCC)<ref name="pmid15172781" /><ref>{{Cite journal |vauthors=Tunio MA, Hashmi A, Qayyum A, Naimatullah N, Masood R |date=September 2012 |title=Low-dose thalidomide in patients with metastatic renal cell carcinoma |journal=The Journal of the Pakistan Medical Association |volume=62 |issue=9 |pages=876β9 |pmid=23139966}}</ref> * [[Glioblastoma multiforme]]<ref name="pmid15172781" /> * [[Prostate cancer]]<ref name="pmid15172781" /> * [[Melanoma]]<ref name="pmid15172781" /> * [[Colorectal cancer]]<ref name="pmid15172781" /> * [[Crohn's disease]]<ref name="pmid15172781" /> * [[Rheumatoid arthritis]]<ref name="pmid15172781" /> * [[Behcet's syndrome]]<ref>{{Cite journal |vauthors=Hamuryudan V, Mat C, Saip S, Ozyazgan Y, Siva A, Yurdakul S, Zwingenberger K, Yazici H |date=March 1998 |title=Thalidomide in the treatment of the mucocutaneous lesions of the BehΓ§et syndrome. A randomized, double-blind, placebo-controlled trial |journal=Annals of Internal Medicine |volume=128 |issue=6 |pages=443β50 |doi=10.7326/0003-4819-128-6-199803150-00004 |pmid=9499327 |s2cid=12089634}}</ref> * [[Breast cancer]]<ref name="pmid15172781" /> * [[Head and neck cancer]]<ref name="pmid15172781" /> * [[Ovarian cancer]]<ref name="pmid15172781" /> * Chronic heart failure<ref name="pmid15172781" /> * Graft-versus-host disease<ref name="pmid15172781" /> * [[Tuberculous meningitis]]<ref>{{Cite journal |vauthors=Wallis RS, Hafner R |date=April 2015 |title=Advancing host-directed therapy for tuberculosis |journal=Nature Reviews. Immunology |volume=15 |issue=4 |pages=255β63 |doi=10.1038/nri3813 |pmid=25765201 |s2cid=1452130}}</ref> {{div col end}}
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