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===Color built using multiple electron detectors=== In some configurations more information is gathered per pixel, often by the use of multiple detectors.<ref name="Antonovsky-1984">{{cite journal |last=Antonovsky |first=A. |year=1984 |title=The application of colour to SEM imaging for increased definition |journal=Micron and Microscopica Acta |volume=15 |issue=2 |pages=77–84 |doi=10.1016/0739-6260(84)90005-4}}</ref> As a common example, secondary electron and backscattered electron detectors are superimposed and a color is assigned to each of the images captured by each detector,<ref name="Danilatos-1986a">{{cite journal |last=Danilatos |first=G.D. |year=1986 |title= Colour micrographs for backscattered electron signals in the SEM|journal=Scanning |volume=9 |issue= 3|pages=8–18|doi=10.1111/j.1365-2818.1986.tb04287.x|s2cid=96315383 }}</ref><ref name="Danilatos-1986b">{{cite journal |last=Danilatos |first=G.D. |year=1986 |title= Environmental scanning electron microscopy in colour|journal=Journal of Microscopy |volume=142 |pages=317–325|doi=10.1002/sca.4950080104|doi-access=free }}</ref> with a result of a combined color image where colors are related to the density of the components. This method is known as density-dependent color SEM (DDC-SEM). Micrographs produced by DDC-SEM retain topographical information, which is better captured by the secondary electrons detector and combine it to the information about density, obtained by the backscattered electron detector.<ref name="Bertazzo-2013">{{Cite journal | last1 = Bertazzo | first1 = S. | last2 = Gentleman | first2 = E. | last3 = Cloyd | first3 = K. L. | last4 = Chester | first4 = A. H. | last5 = Yacoub | first5 = M. H. | last6 = Stevens | first6 = M. M. | doi = 10.1038/nmat3627 | title = Nano-analytical electron microscopy reveals fundamental insights into human cardiovascular tissue calcification | journal = Nature Materials | volume = 12 | issue = 6 | pages = 576–583 | year = 2013 | pmid = 23603848 | pmc = 5833942 | hdl = 10044/1/21901| bibcode = 2013NatMa..12..576B}}</ref><ref>{{cite journal|last1=Bertazzo|first1=Sergio|last2=Maidment|first2=Susannah C. R.|last3=Kallepitis|first3=Charalambos|last4=Fearn|first4=Sarah|last5=Stevens|first5=Molly M.|last6=Xie|first6=Hai-nan|title=Fibres and cellular structures preserved in 75-million–year-old dinosaur specimens|journal=Nature Communications|date=9 June 2015|volume=6|pages=7352|doi=10.1038/ncomms8352|pmid=26056764|pmc=4468865|bibcode=2015NatCo...6.7352B}}</ref> <gallery widths="220px" heights="160px"> File:DDC-SEM of calcified particle in cardiac tissue - BW - 1.jpg|DDC-SEM of calcified particle in cardiac tissue - Signal 1: SE|alt=DDC-SEM of calcified particle in cardiac tissue - Signal 1 : SE File:DDC-SEM_of_calcified_particle_in_cardiac_tissue_-_BW_-_2.jpg| Signal 2: BSE|alt=Signal 2 : BSE File:DDC-SEM of calcified particle in cardiac tissue - orange.jpg|Colorized image obtained from the two previous. Density-dependent color scanning electron micrograph SEM (DDC-SEM) of cardiovascular calcification, showing in orange a calcium phosphate spherical particle (denser material) and, in green, the extracellular matrix (less dense material) File:Cardiovascular calcification - Sergio Bertazzo.tif|Same work with a larger view, part of a study on human cardiovascular tissue calcification </gallery>
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