Editing Pentamidine (section)

== Chemistry ==
Pentamidine isethionate for injection is commercially available as a [[Freeze-drying|lyophilized]], white crystalline powder for reconstitution with sterile water or 5% dextrose. After reconstitution, the mixture should be free from discoloration and precipitation. Reconstitution with sodium chloride should be avoided due to formation of precipitates. Intravenous solutions of pentamidine can be mixed with intravenous HIV medications like [[Zidovudine|zidovidine]] and intravenous heart medications like [[diltiazem]]. However, intravenous solutions of antiviral [[foscarnet]] and antifungal [[fluconazole]] are incompatible with pentamidine.<ref name=":10" /> To avoid side-effects associated with intravenous administration, the solution should be slowly infused to minimize the release of [[histamine]].<ref name=":6" />