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===Indicators=== Many scholars claim that there is a great bias towards the "science and technology mode" (S&T-mode or STI-mode), while the "learning by doing, using and interacting mode" (DUI-mode) is ignored and measurements and research about it rarely done. For example, an institution may be high tech with the latest equipment, but lacks crucial doing, using and interacting tasks important for innovation.<ref>{{Cite web|title=DEVELOPMENT OF INNOVATION - European Journal of Natural History (scientific magazine)|url=https://world-science.ru/en/article/view?id=33506|access-date=2021-04-07|website=world-science.ru}}</ref> A common industry view (unsupported by empirical evidence) is that comparative [[cost-effectiveness]] research is a form of [[price controls|price control]] which reduces returns to industry, and thus limits R&D expenditure, stifles future innovation and compromises new products access to markets.<ref>{{cite journal|pmid=19523121|pmc=2881450|year=2009|last1=Chalkidou|first1=K.|title=Comparative effectiveness research and evidence-based health policy: Experience from four countries|journal=The Milbank Quarterly|volume=87|issue=2|pages=339β67|last2=Tunis|first2=S.|last3=Lopert|first3=R.|last4=Rochaix|first4=L.|last5=Sawicki|first5=P. T.|last6=Nasser|first6=M.|last7=Xerri|first7=B.|doi=10.1111/j.1468-0009.2009.00560.x}}</ref> Some academics claim cost-effectiveness research is a valuable value-based measure of innovation which accords "truly significant" therapeutic advances (i.e. providing "health gain") higher prices than free market mechanisms.<ref>{{cite journal |last1=Roughead |first1=E. |last2=Lopert |first2=R. |last3=Sansom |first3=L. |title=Prices for innovative pharmaceutical products that provide health gain: a comparison between Australia and the United States |journal=Value in Health |year=2007 |volume=10 |issue=6 |pages=514β20 |doi=10.1111/j.1524-4733.2007.00206.x |pmid=17970935 |doi-access=free }}</ref> Such [[value-based pricing]] has been viewed as a means of indicating to industry the type of innovation that should be rewarded from the public purse.<ref>{{cite journal |last=Hughes |first=B. |title=Payers Growing Influence on R&D Decision Making |journal=Nature Reviews Drug Discovery |year=2008 |volume=7 |issue= 11|pages=876β78 |doi=10.1038/nrd2749 |pmid=18974741 |s2cid=10217053 }}</ref> An Australian academic developed the case that national comparative [[cost-effectiveness analysis]] systems should be viewed as measuring "health innovation" as an [[evidence-based policy]] concept for valuing innovation distinct from valuing through competitive markets, a method which requires strong [[anti-trust]] laws to be effective, on the basis that both methods of assessing [[pharmaceutical innovations]] are mentioned in annex 2C.1 of the [[AUSFTA|Australia-United States Free Trade Agreement]].<ref>{{cite journal |last1=Faunce |first1=T. |last2=Bai |first2=J. |last3=Nguyen |first3=D. |title=Impact of the Australia-US Free Trade Agreement on Australian medicines regulation and prices |journal=[[Journal of Generic Medicines]] |year=2010 |volume=7 |issue=1 |pages=18β29 |doi=10.1057/jgm.2009.40 |s2cid=154433476 |url=https://openresearch-repository.anu.edu.au/bitstream/1885/51254/9/Faunce_Journal_Evidence_JGM.pdf.jpg |archive-url=https://web.archive.org/web/20210416220209/https://openresearch-repository.anu.edu.au/bitstream/1885/51254/9/Faunce_Journal_Evidence_JGM.pdf.jpg |archive-date=2021-04-16 |url-status=live }}</ref><ref>{{cite web|author=Faunce TA|title=Global intellectual property protection of 'innovative' pharmaceuticals: Challenges for bioethics and health law in B Bennett and G Tomossy|website=Law.anu.edu.au|publisher=Globalization and Health Springer|year=2006|url=http://law.anu.edu.au/StaffUploads/236-Ch%20Globalisation%20and%20Health%20Fau.pdf|access-date=18 June 2009|archive-url=https://web.archive.org/web/20110414040804/http://law.anu.edu.au/StaffUploads/236-Ch%20Globalisation%20and%20Health%20Fau.pdf|archive-date=14 April 2011}}</ref><ref>{{cite journal |last=Faunce |first=T. A. |title=Reference pricing for pharmaceuticals: is the Australia-United States Free Trade Agreement affecting Australia's Pharmaceutical Benefits Scheme? |journal=Medical Journal of Australia |year=2007 |volume=187 |issue=4 |pages=240β42|pmid=17564579 |doi=10.5694/j.1326-5377.2007.tb01209.x |s2cid=578533 }}</ref>
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