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===Role in disease=== {{Main|Hypertriglyceridemia}} In the human body, high levels of triglycerides in the bloodstream have been linked to [[atherosclerosis]], [[Coronary heart disease|heart disease]]<ref>{{cite news | title=Boston scientists say triglycerides play key role in heart health | newspaper=The Boston Globe | url=https://www.bostonglobe.com/news/science/2014/06/18/boston-researchers-find-that-triglycerides-play-pivotal-role-heart-health/ynrM4QQwIq1fCCoRwMfOAN/story.html |access-date=2014-06-18}}</ref> and [[stroke]].<ref name="drummond" /> However, the relative negative impact of raised levels of triglycerides compared to that of LDL:HDL ratios is as yet unknown. The risk can be partly accounted for by a strong inverse relationship between triglyceride level and HDL-cholesterol level. But the risk is also due to high triglyceride levels increasing the quantity of [[Low-density lipoprotein#LDL size patterns|small, dense LDL particles]].<ref>{{cite journal |vauthors=Ivanova EA, Myasoedova VA, Melnichenko AA, Grechko AV, Orekhov AN |title=Small Dense Low-Density Lipoprotein as Biomarker for Atherosclerotic Diseases |journal= Oxidative Medicine and Cellular Longevity |volume=2017 |page=1273042 |year=2017 |doi=10.1155/2017/1273042 |pmc= 5441126 |pmid = 28572872 |doi-access=free}}</ref>
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