Editing Crohn's disease (section)

====Malnutrition symptoms====

People with Crohn's disease may develop anemia due to [[vitamin B12|vitamin B<sub>12</sub>]], [[folate]], [[iron deficiency]], or due to [[anemia of chronic disease]].<ref name="Lomer2011">{{cite journal | vauthors = Lomer MC | title = Dietary and nutritional considerations for inflammatory bowel disease | journal = The Proceedings of the Nutrition Society | volume = 70 | issue = 3 | pages = 329–335 | date = August 2011 | pmid = 21450124 | doi = 10.1017/S0029665111000097 | doi-access = free | title-link = doi }}</ref><ref name="Gerasimidis2011">{{cite journal | vauthors = Gerasimidis K, McGrogan P, Edwards CA | title = The aetiology and impact of malnutrition in paediatric inflammatory bowel disease | journal = Journal of Human Nutrition and Dietetics | volume = 24 | issue = 4 | pages = 313–326 | date = August 2011 | pmid = 21564345 | doi = 10.1111/j.1365-277X.2011.01171.x | type = Review | doi-access = free | title-link = doi }}</ref> The most common is [[iron deficiency anemia]] from chronic [[blood loss]],<ref name="Lomer2011" /> reduced dietary intake, and persistent inflammation leading to increased [[hepcidin]] levels, restricting [[iron]] absorption in the duodenum.<ref name="Gerasimidis2011" /> As Crohn's disease most commonly affects the [[terminal ileum]] where the vitamin B<sub>12</sub>/[[intrinsic factor]] complex is absorbed, B<sub>12</sub> deficiency may be seen.<ref name="Gerasimidis2011" /> This is particularly common after one has had a surgical procedure to [[Bowel resection|remove the ileum]].<ref name="Lomer2011" /> Involvement of the duodenum and [[jejunum]] can impair the absorption of many other nutrients including [[folate]]. People with Crohn's often also have issues with [[small bowel bacterial overgrowth syndrome]], which can produce micronutrient deficiencies.<ref>{{MedlinePlusEncyclopedia|000222|Small bowel bacterial overgrowth}}</ref><ref name="mimicking">{{cite journal | vauthors = Klaus J, Spaniol U, Adler G, Mason RA, Reinshagen M, von Tirpitz CC | title = Small intestinal bacterial overgrowth mimicking acute flare as a pitfall in patients with Crohn's Disease | journal = BMC Gastroenterology | volume = 9 | issue = 1 | pages = 61 | date = July 2009 | pmid = 19643023 | pmc = 2728727 | doi = 10.1186/1471-230X-9-61 | doi-access = free | title-link = doi }} [[File:CC BY-SA icon.svg|50px]] Text was copied from this source, which is available under a [https://creativecommons.org/licenses/by/2.0/ Creative Commons Attribution 2.0 Generic (CC BY 2.0)] {{Webarchive|url=https://web.archive.org/web/20110223001542/http://creativecommons.org/licenses/by/2.0/ |date=February 23, 2011}} license.</ref>