Editing Zebrafish (section)

====Mitochondrial DNA====
In October 2001, researchers from the [[University of Oklahoma]] published ''D. rerio's'' complete [[mitochondrial DNA]] sequence.<ref name=2001Journal>{{cite journal |vauthors=Broughton RE, Milam JE, Roe BA |title=The complete sequence of the zebrafish (''Danio rerio'') mitochondrial genome and evolutionary patterns in vertebrate mitochondrial DNA |journal=Genome Research |volume=11 |issue=11 |pages=1958–1967 |date=November 2001 |pmid=11691861 |pmc=311132 |doi=10.1101/gr.156801}}</ref> Its length is 16,596 base pairs. This is within 100 base pairs of other related species of fish, and it is notably only 18 pairs longer than the goldfish (''Carassius auratus'') and 21 longer than the [[carp]] (''Cyprinus carpio''). Its gene order and content are identical to the common [[vertebrate]] form of mitochondrial DNA. It contains 13 [[protein]]-coding genes and a noncoding control region containing the [[origin of replication]] for the heavy strand. In between a grouping of five [[tRNA]] genes, a sequence resembling vertebrate origin of light strand replication is found. It is difficult to draw evolutionary conclusions because it is difficult to determine whether base pair changes have adaptive significance via comparisons with other vertebrates' [[nucleotide]] sequences.<ref name=2001Journal/>