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===Ingestion=== In the United States, the [[Center for Science in the Public Interest]] lists the two food preservatives, sulfur dioxide and [[sodium bisulfite]], as being safe for human consumption except for certain asthmatic individuals who may be sensitive to them, especially in large amounts.<ref>{{cite web | title = Center for Science in the Public Interest β Chemical Cuisine | url = http://www.cspinet.org/reports/chemcuisine.htm | access-date = March 17, 2010}}</ref> Symptoms of sensitivity to [[sulfite#Health effects|sulfiting]] agents, including sulfur dioxide, manifest as potentially life-threatening trouble breathing within minutes of ingestion.<ref>{{cite web | title = California Department of Public Health: Food and Drug Branch: Sulfites | url = http://www.cdph.ca.gov/pubsforms/Guidelines/Documents/fdb%20Sulfites.pdf | access-date = September 27, 2013 | url-status = dead | archive-url = https://web.archive.org/web/20120723065412/http://www.cdph.ca.gov/pubsforms/Guidelines/Documents/fdb%20Sulfites.pdf | archive-date = July 23, 2012 }}</ref> Sulphites may also cause symptoms in non-asthmatic individuals, namely [[dermatitis]], [[hives|urticaria]], [[flushing (physiology)|flushing]], [[hypotension]], [[abdominal pain]] and diarrhea, and even life-threatening [[anaphylaxis]].<ref name="pmid24834193">{{cite journal |vauthors=Vally H, Misso NL |title=Adverse reactions to the sulphite additives |journal=Gastroenterol Hepatol Bed Bench |volume=5 |issue=1 |pages=16β23 |date=2012 |pmid=24834193 |pmc=4017440 |doi= |url=}}</ref>
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