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====Underlying liver disease==== Some liver diseases may cause porphyria even in the absence of genetic predisposition. These include [[hemochromatosis]] and [[hepatitis C]]. Treatment of iron overload may be required.<ref name=NIDDK>{{Cite web|url=https://www.niddk.nih.gov/health-information/liver-disease/porphyria|title=Porphyria {{!}} NIDDK|website=National Institute of Diabetes and Digestive and Kidney Diseases|access-date=2018-12-06}}</ref> Patients with the acute porphyrias ([[acute intermittent porphyria|AIP]], [[hereditary coproporphyria|HCP]], [[variegate porphyria|VP]]) are at increased risk over their life for [[hepatocellular carcinoma]] (primary liver cancer) and may require monitoring. Other typical risk factors for liver cancer need not be present.<ref name=NIDDK/>
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