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U.S. Route 22
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===Ohio=== [[Image:USHighway22.JPG|thumb|left|Old US 22 marker located near the intersection of US 22 and [[Ohio State Route 207|SR 207]] in [[Pickaway County, Ohio]]]] US 22 has its westernmost endpoint in downtown [[Cincinnati]]. Its eastbound and westbound endpoints are not at the same intersection. Officially, US 22 eastbound begins on Central Avenue ([[U.S. Route 27|US 27]] northbound/[[U.S. Route 52|US 52]] westbound/[[U.S. Route 127|US 127]] northbound) at 5th Street, then proceeds north, turning east onto 7th Street. Meanwhile, US 22 westbound follows 9th Street and officially ends at Central Avenue<ref>{{Cite web |title=U.S. Route 22 (Hamilton County) - Straight Line Diagram |url=https://www.dot.state.oh.us/TechnicalServices/SLD/SHAMUS00022.pdf |access-date=September 3, 2023 |publisher=[[Ohio Department of Transportation]]}}</ref> (signage designating the end occurs much sooner, approaching Elm Street, [[U.S. Route 42|US 42]] northbound).<ref>{{Google maps|title=104 W 9th Street, Cincinnati, Ohio, United States|url=https://www.google.com/maps?f=q&source=s_q&hl=en&geocode&q=104+w+9th+cincinnati,+ohio&sll=41.950299,-86.418457&sspn=0.495351,1.400757&ie=UTF8&ll=39.105101,-84.515934&spn=0.002019,0.005472&z=18&iwloc=A&layer=c&cbll=39.105099,-84.515933&panoid=jCMFYtwQLCm_6u4cv-sE2w&cbp=12,279.52114318811556,,0,1.8235294117647042|access-date=September 3, 2023}}</ref> From downtown Cincinnati to [[Washington Court House, Ohio|Washington Court House]], US 22 roughly follows the historic 3-C Highway which connected Cincinnati, [[Columbus, Ohio|Columbus]], and [[Cleveland]]. This section is also concurrent with [[Ohio State Route 3|SR 3]]. At Washington Court House, SR 3 and US 22 diverge. US 22 continues to the east through [[Circleville, Ohio|Circleville]] to [[Lancaster, Ohio|Lancaster]]. From Lancaster to [[Zanesville, Ohio|Zanesville]], US 22 roughly follows the route of [[Zane's Trace]], an early pioneer road blazed by [[Ebenezer Zane]] beginning in 1796. Starting just west of [[Cadiz, Ohio|Cadiz]], US 22 becomes a limited-access expressway for the remainder of its approximately {{Convert|30|mi|km}} in Ohio as it approaches and enters [[Greater Pittsburgh]] (with the exception of an at-grade intersection with no stoplights or signs on US 22 and narrowing to two lanes for about {{One2a|{{convert|1|mi|km|spell=in}}}} east of Cadiz). It junctions with [[Ohio State Route 7|SR 7]] for roughly {{One2a|{{convert|1|mi|km|spell=in}}}} along the [[Ohio River]] shoreline in [[Steubenville, Ohio|Steubenville]].
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