Editing Tremor (section)

==Causes==
Tremor can be a symptom associated with disorders in those  parts of the brain that control muscles throughout the body or in particular areas, such as the hands. Neurological disorders or conditions that can produce tremor include [[multiple sclerosis]], [[stroke]], [[traumatic brain injury]], [[chronic kidney disease]] and a number of  [[neurodegenerative disease]]s that damage or destroy parts of the [[brainstem]] or the [[cerebellum]],  [[Parkinson's disease]] being the one most often associated with tremor. Lesions of the Guillain-Mollaret triangle (also called [[myoclonic triangle]] or dentato-rubro-olivary pathway) impair the predictions performed by the [[cerebellum]], causing repetitive muscle discharges by triggering oscillatory activity in the central nervous system.<ref>{{cite journal|last1=Kakei|first1=S|last2=Manto|first2=M|last3=Tanaka|first3=H|last4=Mitoma|first4=H|title=Pathophysiology of Cerebellar Tremor: The Forward Model-Related Tremor and the Inferior Olive Oscillation-Related Tremor.|journal=Front Neurol|date=June 2021|volume=12|pages=12:694653|pmid=34262527|doi=10.3389/fneur.2021.694653|pmc=8273235|doi-access=free}}</ref> Other causes include the use of drugs (such as [[amphetamine]]s, [[cocaine]], [[caffeine]], [[corticosteroid]]s, [[SSRI]]s) or alcohol, [[mercury poisoning]], or the withdrawal of drugs such as alcohol or [[benzodiazepine withdrawal|benzodiazepine]]. Tremors can also be seen in infants with [[phenylketonuria]] (PKU), [[hyperthyroidism|overactive thyroid]] or [[liver failure]]. Tremors can be an indication of [[hypoglycemia]], along with palpitations, sweating and anxiety.<!-- Biochemistry 3rd ed. Lippinscott illustrated reviews. Champe, Harvey, Ferrier. 2005 (for the last sentence) -->
Tremor can also be caused by lack of [[sleep]], lack of [[vitamin]]s, or increased [[stress (biological)|stress]].<ref>{{cite web|first1=Jim |last1=Folk |first2=Marilyn |last2=Folk|title=Body Tremors, Shaking, Trembling, Vibrating Anxiety Symptoms|url=http://www.anxietycentre.com/anxiety-symptoms/body-tremors.shtml|website=Anxietycentre.com|access-date=December 16, 2017}}</ref><ref>{{cite web|last1=Sperling Medical Group|title=Lack of Vitamin B12 can cause tremor symptoms.|url=http://sperlingmedicalgroup.com/2017/05/27/lack-of-vitamin-b12-can-cause-tremor-symptoms/|website=Sperlingmedicalgroup.com|date=27 May 2017|access-date=December 16, 2017}}</ref> Deficiencies of magnesium and [[thiamine]]<ref>National Research Council. 1996. ''Nutrient Requirements of Beef Cattle'', Seventh Revised Ed. Washington, D.C.: National Academy Press.</ref> have also been known to cause tremor or shaking, which resolves when the deficiency is corrected.<ref name=EU2010>{{cite journal|last1=Soar|first1=J|last2=Perkins|first2=GD|last3=Abbas|first3=G|last4=Alfonzo|first4=A|last5=Barelli|first5=A|last6=Bierens|first6=JJ|last7=Brugger|first7=H|last8=Deakin|first8=CD|last9=Dunning|first9=J|last10=Georgiou|first10=M|last11=Handley|first11=AJ|last12=Lockey|first12=DJ|last13=Paal|first13=P|last14=Sandroni|first14=C|last15=Thies|first15=KC|last16=Zideman|first16=DA|last17=Nolan|first17=JP|title=European Resuscitation Council Guidelines for Resuscitation 2010 Section 8. Cardiac arrest in special circumstances: Electrolyte abnormalities, poisoning, drowning, accidental hypothermia, hyperthermia, asthma, anaphylaxis, cardiac surgery, trauma, pregnancy, electrocution.|journal=Resuscitation|date=October 2010|volume=81|issue=10|pages=1400–33|pmid=20956045|doi=10.1016/j.resuscitation.2010.08.015}}</ref> Tremors in animals can also be caused by some spider bites, e.g. the [[redback spider]] of Australia.<ref name="AVRU">{{cite web|url=http://www.avru.org/vetpet/vetpet_vetspider.html|title=Spider Bite|last=Brooks|first=R. |date=January 2008|work=Australian Venom Research Unit|publisher=University of Melbourne|archive-url=https://web.archive.org/web/20150217203444/http://www.avru.org/vetpet/vetpet_vetspider.html|archive-date=17 February 2015 |access-date=27 February 2022}}</ref><!-- cites para -->