Editing Toxoplasmosis (section)

=== Acute ===
Acute toxoplasmosis is often asymptomatic in healthy adults.<ref name="Dupont_2012">{{cite journal |vauthors=Dupont CD, Christian DA, Hunter CA | title = Immune response and immunopathology during toxoplasmosis | journal = Seminars in Immunopathology | volume = 34 | issue = 6 | pages = 793–813 | year = 2012 | pmid = 22955326 | pmc = 3498595 | doi = 10.1007/s00281-012-0339-3 }}</ref><ref name=Dubey2008/> However, symptoms may manifest and are often [[influenza]]-like: swollen [[lymph node]]s, headaches, fever, and fatigue,<ref name="The Mayo Clinic_2015">{{cite web | title = toxoplasmosis | website = [[Mayo Clinic]] | url = http://www.mayoclinic.org/diseases-conditions/toxoplasmosis/basics/symptoms/con-20025859 | url-status = live | archive-url = https://web.archive.org/web/20150908012728/http://www.mayoclinic.org/diseases-conditions/toxoplasmosis/basics/symptoms/con-20025859 | archive-date = 2015-09-08 }}</ref> or [[myalgia|muscle aches]] and pains that last for a month or more. It is rare for a human with a fully functioning [[immune system]] to develop severe symptoms following infection. People with weakened immune systems are likely to experience headache, confusion, poor coordination, seizures, lung problems that may resemble tuberculosis or ''Pneumocystis jirovecii'' pneumonia (a common opportunistic infection that occurs in people with AIDS), or chorioretinitis caused by severe inflammation of the retina (ocular toxoplasmosis).<ref name="The Mayo Clinic_2015"/> Young children and [[Immunodeficiency|immunocompromised]] people, such as those with HIV/AIDS, those taking certain types of [[chemotherapy]], or those who have recently received an [[organ transplant]], may develop severe toxoplasmosis. This can cause damage to the brain ([[encephalitis]]) or the eyes ([[Toxoplasmic chorioretinitis|necrotizing retinochoroiditis]]).<ref name="Jones_2001">{{cite journal |vauthors=Jones JL, Kruszon-Moran D, Wilson M, McQuillan G, Navin T, McAuley JB | title = ''Toxoplasma gondii'' infection in the United States: seroprevalence and risk factors | journal = American Journal of Epidemiology | volume = 154 | issue = 4 | pages = 357–65 | year = 2001 | pmid = 11495859 | doi = 10.1093/aje/154.4.357 | doi-access = free }}</ref> Infants infected via [[Vertically transmitted infection|placental transmission]] may be born with either of these problems, or with nasal malformations, although these complications are rare in newborns. The toxoplasmic [[trophozoite]]s causing acute toxoplasmosis are referred to as [[tachyzoites]], and are typically found in various tissues and body fluids, but rarely in blood or cerebrospinal fluid.<ref>{{cite book |doi=10.1016/B978-0-443-06668-9.50102-2 |date=2006 |isbn=978-0-443-06668-9 |last1=Schwartzman |first1=Joseph D. |last2=Maguire |first2=James H. |title=Tropical Infectious Diseases |chapter=Systemic Coccidia (Toxoplasmosis) |publisher=Elsevier |quote=Tachyzoites are found in all organs in acute infection, most prominently in muscle, including heart, and in the liver, spleen, lymph nodes, and the CNS. }}</ref>

[[Swollen lymph node]]s are commonly found in the neck or under the chin, followed by the armpits and the groin. Swelling may occur at different times after the initial infection, persist, and recur for various times independently of antiparasitic treatment.<ref>{{cite journal | author = Paul M | title = Immunoglobulin G Avidity in Diagnosis of Toxoplasmic Lymphadenopathy and Ocular Toxoplasmosis | journal = Clin. Diagn. Lab. Immunol. | volume = 6 | issue = 4 | pages = 514–8 | date = 1 July 1999 | pmid = 10391853 | pmc = 95718 | doi = 10.1128/CDLI.6.4.514-518.1999 }}</ref> It is usually found at single sites in adults, but in children, multiple sites may be more common. Enlarged lymph nodes will resolve within 1–2 months in 60% of cases. However, a quarter of those affected take 2–4 months to return to normal, and 8% take 4–6 months. A substantial number (6%) do not return to normal until much later.<ref>{{cite web |url=http://ukneqasmicro.org.uk/parasitology/images/pdf/ToxoplasmaSerology/Immunocompetent/Lymphadenopathy.pdf |title=Lymphadenopathy |publisher=UK Neqas Micro |access-date=2016-04-12 |url-status=live |archive-url=https://web.archive.org/web/20160424213931/http://ukneqasmicro.org.uk/parasitology/images/pdf/ToxoplasmaSerology/Immunocompetent/Lymphadenopathy.pdf |archive-date=2016-04-24 }}</ref>