Editing Thermophile (section)

==Thermophile versus mesophile==
Thermophiles can be discriminated from [[mesophile]]s from genomic features. For example, the [[GC-content]] levels in the coding regions of some signature genes were consistently identified as correlated with the temperature range condition when the association analysis was applied to mesophilic and thermophilic organisms regardless of their phylogeny, oxygen requirement, salinity, or habitat conditions.<ref>{{cite journal |author=Zheng H |author2=Wu H |title=Gene-centric association analysis for the correlation between the guanine-cytosine content levels and temperature range conditions of prokaryotic species |journal=BMC Bioinformatics |volume=11 |pages=S7 |date=December 2010 |issue=Suppl 11 |doi=10.1186/1471-2105-11-S11-S7 |pmc=3024870 |pmid=21172057 |doi-access=free }}</ref>