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==Mathematical formulation== The object of a stimulus–response model is to establish a mathematical function that describes the relation ''f'' between the stimulus ''x'' and the [[expected value]] (or other measure of location) of the response ''Y'':<ref name="meyeretal2017">Meyer, A. F., Williamson, R. S., Linden, J. F., & Sahani, M. (2017). Models of neuronal stimulus-response functions: elaboration, estimation, and evaluation. ''Frontiers in systems neuroscience'', 10, 109.</ref> : <math>\mathrm{E}(Y) = f(x)</math> A common simplification assumed for such functions is linear, thus we expect to see a relationship like : <math>\mathrm{E}(Y) = \alpha + \beta x.</math> [[Statistical theory]] for [[linear model]]s has been well developed for more than fifty years, and a standard form of analysis called [[linear regression]] has been developed.
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