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=== Health === A common conception is that all pedigreed cats are less healthy than random-bred cats due to [[inbreeding]]. The Ascent of Cat Breeds: Genetic Evaluations of Breeds and Worldwide Random-bred Populations by Lipinski et al.<ref>{{Cite journal | last1 = Lipinski | first1 = M. J. | last2 = Froenicke | first2 = L. | last3 = Baysac | first3 = K. C. | last4 = Billings | first4 = N. C. | last5 = Leutenegger | first5 = C. M. | last6 = Levy | first6 = A. M. | last7 = Longeri | first7 = M. | last8 = Niini | first8 = T. | last9 = Ozpinar | first9 = H. | last10 = Slater | doi = 10.1016/j.ygeno.2007.10.009 | first10 = M. R. | last11 = Pedersen | first11 = N. C. | last12 = Lyons | first12 = L. A. | title = The ascent of cat breeds: Genetic evaluations of breeds and worldwide random-bred populations | journal = Genomics | volume = 91 | issue = 1 | pages = 12–21 | year = 2008 | pmid = 18060738 | pmc =2267438 }}</ref> showed that pedigreed cats are more inbred than random bred cats. For some breeds such as Singapura and Burmese the genetic diversity is very low. Some breeders take great care to select for the healthiest animals, and this has the potential to reduce the incidence of health issues. An example of this is blindness in the Abyssinian caused by PRA, which have been reduced from 45% to less than 4% in 2008.<ref>{{Cite web |url=http://dobzhanskycenter.bio.spbu.ru/pdf/sjop/MS686%20Narfstrom%20.pdf |title=Archived copy |access-date=2013-05-28 |archive-date=2013-12-17 |archive-url=https://web.archive.org/web/20131217192834/http://dobzhanskycenter.bio.spbu.ru/pdf/sjop/MS686%20Narfstrom%20.pdf |url-status=dead }}</ref> Many of the worst, like [[Polycystic kidney disease|PKD]] in Persians, Hip Dysplasia in British Shorthairs and Maine Coons, [[Hypertrophic cardiomyopathy|HCM]] in Maine Coons, Persians, Exotic Shorthair, British Shorthair, Norwegian Forest Cat, Ragdoll and Bengal, are still present in high frequencies. The frequency of HCM in British Shorthairs are 2.1% for females and 20.4% for males.<ref>{{Cite journal | last1 = Granström | first1 = S. | last2 = Nyberg Godiksen | first2 = M. T. | last3 = Christiansen | first3 = M. | last4 = Pipper | first4 = C. B. | last5 = Willesen | first5 = J. T. | last6 = Koch | first6 = J. | doi = 10.1111/j.1939-1676.2011.0751.x | title = Prevalence of Hypertrophic Cardiomyopathy in a Cohort of British Shorthair Cats in Denmark | journal = Journal of Veterinary Internal Medicine | volume = 25 | issue = 4 | pages = 866–871 | year = 2011 | pmid = 21736622 | doi-access = free }}</ref> The frequency of Hip Dysplasia in Maine Coons is 36.3% <ref>{{cite web|url=http://www.pawpeds.com/healthprogrammes/hd.html|title=PawPeds|work=pawpeds.com|access-date=6 August 2015}}</ref> or 30.2%.<ref>{{cite web|url=http://www.offa.org/stats_hip.html|title=Orthopedic Foundation for Animals|work=offa.org|access-date=6 August 2015|url-status=dead|archive-url=https://web.archive.org/web/20101019034631/http://www.offa.org/stats_hip.html|archive-date=19 October 2010}}</ref> Some breeders use preventive screening, but no studies documenting possible reductions in prevalences exists.
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