Editing Selkirk Rex (section)

== Genetics ==
The Selkirk Rex is defined by an [[autosomal]] dominant woolly rexoid hair (ADWH) abnormality that is characterized by tightly curled [[hair]] shafts.<ref>Gandolfi B, Alhaddad H, Joslin SE, Khan R, Filler S, Brem G, Lyons LA. A splice variant in KRT71 is associated with curly coat phenotype of Selkirk Rex cats. Sci. Rep. 2013;3:2000. {{doi|10.1038/srep02000}}.</ref> A splice variant in the gene KRT71 was found to be associated with the curly coat [[phenotype]]. KRT71 is a crucial gene for [[keratinization]] of the hair follicle. An [[allele]] of this [[gene]] is also responsible for the hairless (hr) [[Sphynx]] and the [[Devon Rex]] (re) hair.<ref>Gandolfi, B. et al. The naked truth: Sphynx and Devon Rex cat breed mutations in KRT71. Mamm Genome 21, 509–515 (2010)</ref> Three [[mutation]]s in KRT71 have now been identified in cats, forming the allelic series, KRT71SADRE > KRT71+ > KRT71re > KRT71hr,<ref>Gandolfi B, Alhaddad H, Joslin SE, Khan R, Filler S, Brem G, Lyons LA. A splice variant in KRT71 is associated with curly coat phenotype of Selkirk Rex cats. Sci. Rep. 2013;3:2000. {{doi|10.1038/srep02000}}.</ref> where SADRE is the suggested locus designation for the Selkirk autosomal dominant rex
21 [[allele]].